MICRO-TAG enzyme complementation enables quantification of cellular drug-target engagement in temperature series
Ivan Babić, Nikolas Bryan, Claire Cunningham, Avery Sampson et autres
2 citationsSLAS DISCOVERY
Avery Sampson
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24Publications signalées
238Citations signalées
1Affiliations récentes
Institutions déclarées
Domaines associés
Acute Myeloid Leukemia ResearchProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysHistone Deacetylase Inhibitors ResearchAdvanced Biosensing Techniques and Applications
Publications récentes
MICRO-TAG enzyme complementation enables quantification of cellular drug-target engagement in temperature series
Ivan Babić, Nikolas Bryan, Claire Cunningham, Avery Sampson et autres
2 citationsbioRxiv (Cold Spring Harbor Laboratory)
Characterization of E1 enzyme dependencies in mutant-UBA1 human cells reveals UBA6 as a novel therapeutic target in VEXAS syndrome
Courtnee Clough, Claire Cunningham, Sophia Y Philbrook, Kathleen Hueneman et autres
8 citationsLeukemia
The IRAK4 long isoform as widely upregulated in non-splicesome mutated acute myeloid leukemia and as altered by hypomethylating agent therapy.
Eric Vick, Sean Walulik, Avery Sampson, Aishlin Hassan et autres
0 citationsJournal of Clinical Oncology
Ubiquitin-conjugating enzyme UBE2N modulates proteostasis in immunoproteasome-positive acute myeloid leukemia
Chiharu Ishikawa, Laura Barreyro, Avery Sampson, Kathleen Hueneman et autres
15 citationsJournal of Clinical Investigation
Microbial metabolite drives ageing-related clonal haematopoiesis via ALPK1
Puneet Agarwal, Avery Sampson, Kathleen Hueneman, Kwangmin Choi et autres
46 citationsNature
Abstract 5480: Live cell real-time quantification of drug-target engagement for rapid drug discovery
Ivan Babić, Nikolas Bryan, Claire Cunningham, Avery Sampson et autres
0 citationsCancer Research
Dysregulated innate immune signaling cooperates with RUNX1 mutations to transform an MDS-like disease to AML
Laura Barreyro, Avery Sampson, Kathleen Hueneman, Kwangmin Choi et autres
15 citationsiScience
Abstract 3092: MICRO-TAG: A novel fluorescence-based real-time cellular target engagement platform for drug discovery
Ivan Babić, Nikolas Bryan, Claire Cunningham, Avery Sampson et autres
0 citationsCancer Research
UBE2N Regulates Oncoprotein Networks in Myeloid Malignancies
Chiharu Ishikawa, Laura Barreyro, Avery Sampson, Kathleen Hueneman et autres
0 citationsBlood
Paralog-specific signaling by IRAK1/4 maintains MyD88-independent functions in MDS/AML
Joshua Bennett, Chiharu Ishikawa, Puneet Agarwal, Jennifer Yeung et autres
54 citationsBlood
Inactivation of p53 provides a competitive advantage to del(5q) myelodysplastic syndrome hematopoietic stem cells during inflammation
Tomoya Muto, Callum S. Walker, Puneet Agarwal, Eric Vick et autres
10 citationsHaematologica
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