Naomi Iacoponi

Diagnostic challenges in infant death associated with maternal cocaine abuse during pregnancy and lactation: a forensic case report and review of the literature

Naomi Iacoponi, Rebecca Maggi, Vincenzo Nardini, Silvio Chericoni et autres

Introduction: Maternal cocaine abuse during pregnancy and lactation represents a critical public health crisis. Recent 2024-2025 data indicate approximately 4.3 million users in the United States and 2.7 million young adults in Europe. While epidemiological evidence suggests an independent association between prenatal …

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The Shrinking Blind Spot: How Freeze–Thaw Obscures Microscopic Evidence of Ante-Mortem Ecchymosis

Naomi Iacoponi, Sara Luiza Giacomelli, Emanuela Turillazzi, Marco Di Paolo

Background/Objectives: Histological examination constitutes a fundamental methodology for establishing the vitality of a lesion. In cases where the corpse is preserved for an extended duration of time prior to the post-mortem evaluation, particularly if the body has undergone freezing and thawing cycles, …

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The Shrinking Blind Spot: How Freeze-Thaw Obscures Microscopic Evidence of Ante-Mortem Ecchymosis

Naomi Iacoponi, Sara Luiza Giacomelli, Emanuela Turillazzi, Marco Di Paolo

Background/Objectives: Histological examination constitutes a fundamental methodology for establishing the vitality of a lesion. In cases where the corpse is preserved for an extended duration of time prior to the post-mortem evaluation, particularly if the body has undergone freezing and thawing cycles, …

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Affidabilità dell'espressione della Glicoforina A come marker di vitalità nelle lesioni contusive in cadaveri sottoposti a cicli di congelamento-scongelamento

Naomi Iacoponi

La diagnosi di vitalità rappresenta un quesito cardine nella pratica medico-legale e istopatologica. In alcuni casi, a causa di peculiari esigenze processuali, un cadavere può essere sottoposto a metodi di conservazione in celle refrigerate a -20°C e al successivo scongelamento prima dell’esecuzione …

Physician-assisted suicide in Italy: where do we stand and where do we want to go?

Emanuela Turillazzi, Donato Morena, Naomi Iacoponi, Vittorio Fineschi

Physician-assisted suicide (PAS) remains a subject of global debate and ethical controversy, alongside other end-of-life issues such as euthanasia, palliative care, access to health and social care services, and, importantly, patient autonomy. Within this context, PAS is defined as the practice in …

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From scarless surgery to legal pressure: The obligation for cosmetic outcomes in minimally invasive procedures?

Marco Di Paolo, Naomi Iacoponi, Ugo Boggi

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COVID-19 History & Epidemiology

Emanuela Turillazzi, Julia Lazzari, Naomi Iacoponi, Vittorio Fineschi

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Boar hunt or Manhunt? fatality during a wild boar hunting expedition. Need for a multidisciplinary forensic approach

Naomi Iacoponi, Valentina Bugelli, Rosario Fico, Claudia Giaconi et autres

Hunting is commonly regarded as a prevalent leisure activity in many Western countries. Moreover, hunting-related shooting injuries and fatalities are an important issue in the forensic world. However, there is limited research investigating the necessity of a multidisciplinary approach to provide a …

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Butane-related deaths in post-mortem investigations: A systematic review

Naomi Iacoponi, Fabio Del Duca, Ilaria Marcacci, Carla Occhipinti et autres

Volatile substance abuse is widespread among adolescents due to its easy availability and methods of consumption. Inhalant abuse represents a current problematic issue, causing significant morbidity and mortality due to direct toxicity on several target organs and displacement of gas which results …

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miRNAs and Substances Abuse: Clinical and Forensic Pathological Implications: A Systematic Review

Carla Occhipinti, Raffaele La Russa, Naomi Iacoponi, Julia Lazzari et autres

Substance addiction is a chronic and relapsing brain disorder characterized by compulsive seeking and continued substance use, despite adverse consequences. The high prevalence and social burden of addiction are indisputable; however, the available intervention is insufficient. The modulation of gene expression and …

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State-of-the-Art on Wound Vitality Evaluation: A Systematic Review

Aniello Maiese, Alice Chiara Manetti, Naomi Iacoponi, Eleonora Mezzetti et autres

The vitality demonstration refers to determining if an injury has been caused ante- or post-mortem, while wound age means to evaluate how long a subject has survived after the infliction of an injury. Histology alone is not enough to prove the vitality …

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