Joon S. Lee

Integrated Symbiotic Pleiotropy: Long Non-Coding RNAs and Disordered Proteins Interweaving the Functional Layers of the Eukaryotic Cell

Evelina Daskalova, Joon S. Lee, Gergana Zahmanova, Ivan Nikiforov Minkov

Long non-coding RNAs (lncRNAs) and RNA-protein complexes (RNPs) are increasingly recognized as central to the regulatory complexity of modern eukaryotes. This review proposes that the remarkable diversity of eukaryotic systems arises from the long-term integration of ancient RNA/RNP mechanisms, layered with innovations …

bg, us (code pays fourni par la source)

Genome-Wide CRISPR Screen Identifies KEAP1 Perturbation as a Vulnerability of ARID1A-Deficient Cells

Louis-Alexandre Fournier, Forouh Kalantari, James P. Wells, Joon S. Lee et autres

ARID1A is the core DNA-binding subunit of the BAF chromatin remodeling complex and is mutated in about 8% of all cancers. The frequency of ARID1A loss varies between cancer subtypes, with clear cell ovarian carcinoma (CCOC) presenting the highest incidence at > …

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Expression complementation of gene presence/absence polymorphisms in hybrids contributes importantly to heterosis in sunflower

Joon S. Lee, Mojtaba Jahani, Kaichi Huang, Jennifer R. Mandel et autres

INTRODUCTION: Numerous crops have transitioned to hybrid seed production to increase yields and yield stability through heterosis. However, the molecular mechanisms underlying heterosis and its stability across environments are not yet fully understood. OBJECTIVES: This study aimed to (1) elucidate the genetic …

ca, us, fr (code pays fourni par la source)

Outcomes in Multivessel Coronary Disease Stratified by The Society of Thoracic Surgeons Risk

Saloni Kapoor, Jianhui Zhu, Arman Kilic, Catalin Toma et autres

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Long term mortality and readmissions after transcatheter aortic valve replacement

Mourad Hussein Senussi, John T. Schindler, Ibrahim S. Sultan, Ahmad Masri et autres

Background: Readmissions following transcatheter aortic valve replacement (TAVR) are common but detailed analysis of cardiac and non-cardiac inpatient readmissions beyond thirty days to different levels of care are limited. Methods: Our study population was 1,037 consecutive patients who underwent TAVR between 2011–2017 …

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Symplocarpus koreanus (Araceae; Orontioideae), a new species based on morphological and molecular data

Joon S. Lee, Seon‐Hee Kim, Yongsung Kim, Youl Kwon et autres

Symplocarpus koreanus (Araceae; Orontioideae) from Korea is described as new.Symplocarpus koreanus has long been considered to be conspecific with S. renifolius in Japan, but phylogenetic, morphological, and cytological data indicate its taxonomic distinction.Compared to S. renifolius, S. koreanus has a much smaller …

kr, us, jp (code pays fourni par la source)

Genome-Wide Expression and Alternative Splicing in Domesticated Sunflowers (Helianthus annuus L.) under Flooding Stress

Joon S. Lee, Lexuan Gao, Laura Melissa Guzman, Loren H. Rieseberg

Approximately 10% of agricultural land is subject to periodic flooding, which reduces the growth, survivorship, and yield of most crops, reinforcing the need to understand and enhance flooding resistance in our crops. Here, we generated RNA-Seq data from leaf and root tissue …

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Global insights into duplicated gene expression and alternative splicing in polyploid Brassica napus under heat, cold, and drought stress

Joon S. Lee, Keith L. Adams

Abstract Polyploidy has been a prevalent process during plant evolution and it has made a major impact on the structure and evolution of plant genomes. Many important crop plants are polyploid. There is considerable interest in expression patterns of duplicated genes in …

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Impact of Combined Pre and Postcapillary Pulmonary Hypertension on Survival after Transcatheter Aortic Valve Implantation

Ibrahim S. Sultan, Miho Fukui, Valentino J. Bianco, James A. Brown et autres

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Baseline global longitudinal strain by computed tomography is associated with post transcatheter aortic valve replacement outcomes

Miho Fukui, Jeffrey Xu, Floyd W. Thoma, Ibrahim S. Sultan et autres

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New insights into the phylogeny and biogeography of subfamily Orontioideae (Araceae)

Joon S. Lee, Seon‐Hee Kim, Sangryong Lee, Masayuki Maki et autres

Abstract Proto‐Araceae, the earliest diverged lineage within the family Araceae, includes two subfamilies, Gymnostachydoideae (one species) and Orontioideae (eight species). Based on an extensive sampling (a total of 198 accessions) of six chloroplast non‐coding regions (5799 aligned sites), we assessed phylogenetic relationships …

kr, jp, ru, us (code pays fourni par la source)

Pulmonary Hypertension Persistency in Severe Aortic Stenosis Patients Treated With TAVR

Ahmad Masri, Thomas G. Gleason, Joon S. Lee, João L. Cavalcante

us (code pays fourni par la source)