Accès ouvert
2026
article
OpenAlex
Richard J. Miron, Paras Ahmad, Anton Sculean
BACKGROUND: Extracellular vesicles (EVs), including exosomes, have emerged as fundamental regulators of cell-to-cell communication and are increasingly recognized for their therapeutic and diagnostic promise. While EV research has expanded remarkably over the past two decades, the discipline is rooted in a much …
ch, us
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron
BACKGROUND: Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell-to-cell communication with potential roles in both enhancing and …
us, ch
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Paras Ahmad
us
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Nathan E. Estrin, Paras Ahmad, Savannah Laurey, Nima Farshidfar et autres
BACKGROUND: Periodontitis is a chronic multifactorial inflammatory condition resulting in the gradual breakdown of periodontal supporting structures. Although non-surgical periodontal therapy (NSPT) is the gold standard first therapeutic option, its effectiveness can be limited in moderate-to-severe cases, hence necessitating the application of …
2026
review
OpenAlex
Paras Ahmad
us
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Paras Ahmad
OBJECTIVES: This review synthesizes current biomarker-mediated, mechanistic, and clinical evidence on extracellular vesicles (EVs) derived from saliva and gingival crevicular fluid (GCF) as potential diagnostic and functional regulators in periodontal diseases (PD). DATA: Preclinical and clinical studies assessing EV-related molecular signatures, biological …
us
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang et autres
BACKGROUND: Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement. This review aims to offer a …
us, ch, cn
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang et autres
Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement. This review aims to offer a …
mm, gb
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Paras Ahmad, Catherine Davies, Anton Sculean, Richard J. Miron
Abstract Background Alopecia is a prevalent condition correlated with significant psychosocial challenges, while contemporary treatments exhibit variable efficacy, require extended use, and may cause adverse effects. This review aimed to comprehensively assess exosome‐mediated interventions as a novel cell‐free regenerative approach for hair …
us, Afrique du Sud, ch
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Paras Ahmad, Catherine Davies, Anton Sculean, Richard J. Miron
Background Alopecia is a prevalent condition correlated with significant psychosocial challenges, while contemporary treatments exhibit variable efficacy, require extended use, and may cause adverse effects. This review aimed to comprehensively assess exosome-mediated interventions as a novel cell-free regenerative approach for hair regeneration …
Accès ouvert
2026
article
OpenAlex
Paras Ahmad, Anton Sculean, Richard J. Miron
BACKGROUND: Regenerative dentistry is shifting from cell-based strategies to cell-free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication. This review aimed to offer a comprehensive synthesis of …
us, ch
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Paras Ahmad, Anton Sculean, Richard J. Miron
Background Regenerative dentistry is shifting from cell-based strategies to cell-free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication. This review aimed to offer a comprehensive synthesis of …
mm, gb
(code pays fourni par la source)