Duc Thinh Khong

Multiplexed Nanosensors for Real‐Time Monitoring of VOC‐Mediated Signalling Response in Plants

Mervin Chun‐Yi Ang, Jolly Madathiparambil Saju, Sayyid Mohaideen, Niha Dhar et autres

ABSTRACT To enhance crop performance, intercropping strategies leverage volatile organic compound (VOC)‐driven interactions with companion plants that constitutively emit VOCs. Despite the agricultural importance, the mechanisms and kinetics of VOC‐mediated sensory transduction in receiver plants eavesdropping on neighbouring non‐kin emitters remain largely …

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Real-Time Nanosensor-Mediated Monitoring of Jasmonic Acid Accumulation in Interplant Wounding

Mervin Chun‐Yi Ang, Jolly Madathiparambil Saju, Sayyid Mohaideen, Sarangapani Sreelatha et autres

Jasmonic acid (JA) is a key phytohormone mediating plant defense, and its signalling can be induced in unstressed plants by volatile organic compounds (VOCs) released from stressed neighbors. To study these dynamics, we developed and validated a selective, real-time nanosensor for JA …

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Data for: Silk Microneedles Carrying SWNT-CoPhMoRe Nanosensors for Early Detection of Shade Avoidance Syndrome In Planta.

Raju Cheerlavancha, Benny Jian Rong Sng, Duc Thinh Khong, Michael S. Strano et autres

This dataset contains raw time-lapse TIFF stacks from microneedle near-infrared (NIR) fluorescence imaging experiments used in the manuscript "Silk Microneedles Carrying SWNT-CoPhMoRe Nanosensors for Early Detection of Shade Avoidance Syndrome In Planta". The data are organized by manuscript figure and experimental condition …

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Data for: Silk Microneedles Carrying SWNT-CoPhMoRe Nanosensors for Early Detection of Shade Avoidance Syndrome In Planta.

Raju Cheerlavancha, Benny Jian Rong Sng, Duc Thinh Khong, Michael S. Strano et autres

This dataset contains raw time-lapse TIFF stacks from microneedle near-infrared (NIR) fluorescence imaging experiments used in the manuscript "Silk Microneedles Carrying SWNT-CoPhMoRe Nanosensors for Early Detection of Shade Avoidance Syndrome In Planta". The data are organized by manuscript figure and experimental condition …

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Fluorescent Nanosensor for Indole‐3‐Propionic Acid Detection in Gut Health Monitoring

Mervin Chun‐Yi Ang, Jonathan Wei Jie Lee, Sayyid Mohaideen, Gabriel Sánchez-Velázquez et autres

The gut microbiota plays a pivotal role in bio-transforming dietary components, including tryptophan, an essential amino acid that undergoes microbial metabolism. Microbial metabolism of tryptophan yields indole-3-propionic acid (IPA), an emerging biomarker for gut inflammation. Current IPA detection relies on expensive, time-consuming …

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Analysis of Nanosensor-Reported Waveforms for Plant Wounding

Cody L. Ritt, Yile Jiang, Gabriel Sánchez-Velázquez, Thomas Porter et autres

Using nanosensors in living plants allows the real-time detection of internal reactive oxygen species (e.g., hydrogen peroxide) signaling in response to environmental stressors. The time-dependent pulse of hydrogen peroxide (H 2 O 2 ) constitutes a signaling waveform; however, standardized methods of …

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In Vivo Detection of IAA Using IAA Nanosensor

Benny Jian Rong Sng, Duc Thinh Khong, Thomas Porter, Michael S. Strano et autres

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Using Molecular Probe Adsorption to Characterize the Nanoparticle Corona Phase and Molecular Recognition

Gabriel Sánchez-Velázquez, Duc Thinh Khong, Minkyung Park, Xiaojia Jin et autres

The nanoparticle corona─a molecular layer adsorbed on nanoparticle surfaces─is critical for controlling molecular interactions and enabling applications in catalysis, nanoparticle separations, and sensing technologies. However, to date, characterizing the adsorbed surface area occupied by the corona phase has been difficult and not …

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Transient Boronate Ester Mask Enables a Streamlined First Total Synthesis of Isoacteoside

Madhu Babu Tatina, Duc Thinh Khong, Mardi Santoso, Zaher M. A. Judeh

The first total synthesis of phenylpropanoid glycoside (PhG) isoacteoside 1 is presented. The synthesis employs a novel protection-free strategy leveraging phenylboronic acid as a transient masking agent to enable regioselective mono-rhamnosylation and caffeoylation. This method circumvents the need for traditional multi-step protection …

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A Near-Infrared Fluorescent Nanosensor for Direct and Real-Time Measurement of Indole-3-Acetic Acid in Plants

Duc Thinh Khong, Kien Van Vu, Benny Jian Rong Sng, Ian Kin Yuen Choi et autres

Auxin, particularly indole-3-acetic acid (IAA), is a phytohormone critical for plant growth, development, and response to environmental stresses like shade avoidance syndrome and thermomorphogenesis. Despite its importance, there is no existing method that allows for convenient and direct detection of IAA in …

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Concise first total synthesis of phenylethanoid glycosides parvifloroside A and crassifolioside

Duc Thinh Khong, Madhu Babu Tatina, Zaher M. A. Judeh

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Concise Total Synthesis of Phenylethanoid Glycoside Acteoside

Duc Thinh Khong, H F Marlow, Zaher M. A. Judeh

Acteoside is a prominent phenylethanoid glycoside (PhG) with diverse pharmacological activities. However, its chemical synthesis has been challenging due to the reliance on extensive protection/deprotection strategies, leading to lengthy routes and low overall yields. Herein, we present a streamlined and efficient synthetic …

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