2019
conference-abstract
OpenAlex
Chan C. Whiting, Davorka Messmer, Traci Olafson, Derek Metzger et autres
Tumors evolve to modulate metabolism to promote their own survival and to suppress tumor-specific immunity. Hypoxic conditions in the tumor microenvironment (TME) induce fatty acid oxidation (FAO), and diverse malignancies are reliant on this metabolic pathway. Additionally, suppressive immune cell populations including …
us, ca
(code pays fourni par la source)
2019
conference-abstract
OpenAlex
Chan C. Whiting, Davorka Messmer, Traci Olafson, Derek Metzger et autres
Abstract Tumors evolve to modulate metabolism to promote their own survival and to suppress tumor-specific immunity. Hypoxic conditions in the tumor microenvironment (TME) induce fatty acid oxidation (FAO), and diverse malignancies are reliant on this metabolic pathway. Additionally, suppressive immune cell populations …
ca, us
(code pays fourni par la source)
2010
article
OpenAlex
Anindya Bhattacharya, Michael P. Maher, William A. Eckert, Traci Olafson et autres
Purinergic receptor subtype 7 (P2X7) is expressed on immune/glial cells and is hypothesized to modulate both inflammatory and neuropathic pain as seen by genetic disruption and pharmacological intervention. In this study, we report the characterization of a novel P2X7 receptor antagonist discovered …
us
(code pays fourni par la source)