Nathan W. Rojek

Pyoderma Gangrenosum Phenotype Classification

Ahana Gaurav, Samantha Gregoire, Eric Xia, Basil Alex McIntosh et autres

Importance: Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis characterized by sterile ulcerative skin lesions. Multiple comorbidities and clinical features have been associated with PG, but no standardized guidelines exist for classifying PG phenotypes. Objective: To develop an expert-established classification framework for …

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Representation of medical specialties in dean’s cabinets at the top 40 NIH-funded United States medical schools

Anagha B. Thiagarajan, Luke Horton, Ajay Sharma, Nathan W. Rojek

BACKGROUND: Academic leadership within medical schools shapes institutional culture, policy, and educational priorities. While demographic diversity has been studied, specialty representation in leadership is less understood. This study evaluates the distribution of medical specialties in dean's cabinets at the top 40 National …

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Scalp Psoriasis Supplemental Table

Rachel Greene, Nicolette Pepin, Reid Oldenberg, Genevieve J. Kaunitz et autres

Summary of Scalp Specific Outcomes of Systemic Therapies for Psoriasis

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Scalp Psoriasis Supplemental Table

Rachel Greene, Nicolette Pepin, Reid Oldenberg, Genevieve J. Kaunitz et autres

Summary of Scalp Specific Outcomes of Systemic Therapies for Psoriasis

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Flagellate erythema-like persistent eruption of Still's disease treated with a Janus kinase inhibitor

Alexa Kassels, Christine Pham, Deborah J. Moon, Bonnie A. Lee et autres

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Representation of Medical Specialties in Dean’s Cabinets at the Top 40 NIH-Funded United States Medical Schools

Anagha Thiagarajan, Luke Horton, Ajay Sharma, Nathan W. Rojek

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Development of a Skin-Directed Scoring System for Stevens-Johnson Syndrome and Epidermal Necrolysis

Lisa C. Zaba, Sergey Rekhtman, Caroline A. Nelson, Stephanie T. Le et autres

Importance: Scoring systems for Stevens-Johnson syndrome and epidermal necrolysis (EN) only estimate patient prognosis and are weighted toward comorbidities and systemic features; morphologic terminology for EN lesions is inconsistent. Objectives: To establish consensus among expert dermatologists on EN terminology, morphologic progression, and …

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Review of category A bioweapons with cutaneous features: Epidemiology, clinical presentation, and contemporary management strategies

Sara Osborne, Olivia Kam, Shivani Thacker, Raquel Wescott et autres

Major health organizations recognize various pathogens as potential bioweapons. Category A bioweapons (anthrax, plague, smallpox, tularemia, and viral hemorrhagic fevers) are the highest priority due to their ease of spread and high mortality rates. As these conditions have cutaneous manifestations, dermatologists may …

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A rare case of pediatric cutaneous bullous mastocytosis

Jennifer Roux, Christine Pham, Katerina Yale, Nathan W. Rojek et autres

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Relapsing toxic epidermal necrolysis following COVID-19

Feben Messele, Luke Horton, Ajay Sharma, Michelle S. Min et autres

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are dermatologic emergencies classically triggered by medications, most commonly: antibiotics, antiepileptics, nonsteroidal antiinflammatory drugs, allopurinol, and immune checkpoint inhibitors.1 Infection may also be an inciting factor, with COVID-19 particularly associated with an increase in …

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Round Bodies Detected by Treponema pallidum Immunohistochemical Stain in Two Cases of Cutaneous Syphilitic Gummata

Suzanne W. Birmingham, Lina Saeed, Charles M. Thurlow, Kendra Vilfort et autres

ABSTRACT: Tertiary syphilis may present a diagnostic challenge due to negative nontreponemal serologies in up to 30% of cases and frequent lack of identifiable spirochetes on histopathology or other direct detection tests. We report 2 cases of round bodies staining with Treponema …

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Osimertinib tolerance in a patient with Stevens Johnson syndrome during osimertinib therapy after treatment with pembrolizumab

Michael A. Lopez, Garo Hagopian, Linda Doan, Benjamin J. Lee et autres

BACKGROUND: Osimertinib has emerged as an important tool in the treatment of non-small cell lung cancers (NSCLC) with certain activating mutations of epidermal growth factor receptor (EGFR). However, Osimertinib may cause adverse effects, including severe cutaneous adverse reactions (SCARs) such as Stevens-Johnson …

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