Laixi Zhao

A Covalent Brush‐on‐Brush Polymer Programs Ordered Intracellular Activation of a Mitochondria‐Disrupting Peptide

Rui Xu, Lubin Ning, Laixi Zhao, Zilin Lu et autres

ABSTRACT Can the order in which a material encounters distinct biological environments be encoded directly into its covalent architecture? Intracellular peptide effectors acting at defined subcellular sites require activation logic that follows this order, yet many responsive carriers couple multiple functional changes …

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A Covalent Brush‐on‐Brush Polymer Programs Ordered Intracellular Activation of a Mitochondria‐Disrupting Peptide

Rui Xu, Lubin Ning, Laixi Zhao, Zilin Lu et autres

Can the order in which a material encounters distinct biological environments be encoded directly into its covalent architecture? Intracellular peptide effectors acting at defined subcellular sites require activation logic that follows this order, yet many responsive carriers couple multiple functional changes to …

cn (code pays fourni par la source)

Brush‐on‐Brush Architecture Enables Durable and Reversible Aptamer Therapeutics With Minimal PEG Associated Immunogenicity

Gengzhi Ren, Rui Xu, Laixi Zhao, Lubin Ning et autres

We present a "Brush-on-Brush" (BOB) nanocarrier as a next-generation alternative to PEGylation for nucleic acid aptamer therapeutics. This architecture, comprising aptamers and dense brush-shaped oligo(ethylene glycol) (b-OEG) side chains co-grafted onto a peptide backbone, was validated using the thrombin-binding HD1 aptamer. BOB-HD1 …

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Mucin-inspired bottlebrush polymer hydrogel for postoperative adhesion prevention

Gengzhi Ren, Rui Xu, Pan Zhang, Laixi Zhao et autres

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Ecotypic Research and Applied Value of the Forage Germplasm Resources

Laixi Zhao, Yuqing Wang, Ying De, XU Chun-bo

Distribution Law and Utilizable Potentialities of Three Kinds of Clover Germplasm Resources in Xinjiang

Laixi Zhao, Yuqing Wang, XU Chun-bo, Ying De

Evaluation of Lamb Performance and Forage Quality in Rotational Grazing Systems

Yuping Rong, Laixi Zhao