Yoshihiro Goda

Post‐Endoscopic Retrograde Cholangiopancreatography Bleeding After Endoscopic Stone Removal in Dialysis Patients: A Multicenter Retrospective Study

Masaki Nishimura, Haruo Miwa, Takashi Kaneko, Endo Kazuki et autres

Objectives: Post-endoscopic retrograde cholangiopancreatography (post-ERCP) bleeding occurs more frequently in dialysis patients than in non-dialysis patients. This study aimed to identify risk factors for post-ERCP bleeding following stone removal in patients undergoing dialysis. Methods: This multicenter retrospective study enrolled 102 consecutive dialysis …

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Feasibility of Peroral Pancreatoscopy Using the 9-Fr eyeMAX for Surgical Planning in Main-Duct and Mixed-Type Intraductal Papillary Mucinous Neoplasms

Haruo Miwa, Kuniyasu Irie, Tomoko Fujiyoshi, Nene Sakai et autres

Background/Objectives: The role of peroral pancreatoscopy (POPS) in patients with main-duct and mixed-type intraductal papillary mucinous neoplasm (MD/mixed-IPMN) remains unclear. This retrospective multicenter case series aimed to evaluate the feasibility and safety of POPS using the 9-Fr eyeMAX and to describe additional …

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Feasibility of Endoscopic Closure Method Using Low Cost Clips With Thread for Post Gastric Endoscopic Submucosal Dissection: A Pilot Study

Ryosuke Ikeda, Hiroaki Kaneko, Hiroki Sato, Yuto Matsuoka et autres

Background and Aim: Endoscopic closure in gastric endoscopic submucosal dissection (ESD) is useful to prevent delayed bleeding. Although several closure methods have been reported, their cost remains a significant issue. In this pilot study, we developed a low-cost endoscopic closure (LoCC) method …

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Risk factors for gastric cancer diagnosed more than 10 years after eradication therapy of Helicobacter pylori

Sho Onodera, Soichiro Sue, Hiroaki Kaneko, Yushi Kanemaru et autres

Introduction Risk factors for gastric cancer in the long-term post–Helicobacter pylori (H. pylori) eradication cohort remain unclear. This study aimed to identify risk factors for gastric cancer in the long-term post-eradication cohort.Methods We conducted a retrospective case–control study. Patients who underwent endoscopic …

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Proton Pump Inhibitor‐Induced Fundic Gland Polyps With Massive Bleeding Regressed on Alternative Histamine 2 Receptor Antagonist Therapy

Ryosuke Ikeda, Hiroaki Kaneko, Hiroki Sato, Yuto Matsuoka et autres

We report a case of massive bleeding from proton pump inhibitor (PPI)-induced fundic gland polyps (FGPs) that regressed after switching to a histamine-2 receptor antagonist (H2RA). A 46-year-old man with antiphospholipid syndrome had been receiving warfarin and lansoprazole for 4 years. Esophagogastroduodenoscopy …

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Endoscopic transpapillary gallbladder drainage for localized acute cholecystitis confined by segmental adenomyomatosis using a novel rotatable sphincterotome

Yoshihiro Goda, Kuniyasu Irie, Yuto Matsuoka, Tomomi Hamaguchi et autres

Endoscopic transpapillary gallbladder drainage (ETGBD) for localized acute cholecystitis in the fundal region confined by a segmental adenomyomatosis (ADM)-related stricture is technically challenging due to the difficulty of guidewire passage through the stricture. When the catheter tip is not directed toward the …

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Total synthesis and biological evaluation of (−)-enigmazole B

Yoshihiro Goda, Keita Sakamoto, Keisuke Murata, Haruhiko Fuwa

Abstract Total synthesis of (−)-enigmazole B, isolated from a Papua New Guinean sponge, Cinachyrella enigmatica, has been achieved for the first time. The macrocyclic skeleton of the target compound was synthesized by exploiting a Sonogashira cross-coupling of an (E)-enol tosylate and a …

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Balloon enteroscope insertion over an endoscopic nasobiliary drainage tube in patients with surgically altered anatomy

Yoshihiro Goda, Kuniyasu Irie, Yuto Matsuoka, Tomomi Hamaguchi et autres

Scope insertion over an endoscopic nasobiliary drainage (ENBD) tube can facilitate the exchange to internal drainage without the need for selective guidewire reinsertion [ 1 ] [ 2 ] [ 3 ]. During the procedure, an assistant pushes or pulls the ENBD …

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Development of a novel PIK3CA-mutated pancreatic tumor mouse model and evaluation of the therapeutic effects of a PI3K inhibitor

Yoshimasa Suzuki, Makoto Sugimori, Yushi Kanemaru, Sho Onodera et autres

Pancreatic ductal adenocarcinoma (PDAC) is a fatal malignancy. Personalized medicine based on genetic mutations is required to improve its prognosis. The PI3K/AKT pathway plays a crucial role in cancer progression. While PI3K inhibitors have been developed for several malignancies, none have been …

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Feasibility of Novel Slim Peroral Cholangiopancreatoscopy for the Diagnosis of Pancreatobiliary Disease

Haruo Miwa, Kazuya Sugimori, Kuniyasu Irie, Yoshihiro Goda et autres

ABSTRACT Objectives To evaluate the clinical outcomes of peroral cholangiopancreatoscopy (POCPS) using the 9‐Fr eyeMAX for the diagnosis of pancreatobiliary diseases. Methods This retrospective study enrolled 43 patients who underwent POCPS using the 9‐Fr eyeMAX for diagnostic procedures at two tertiary referral …

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CLINICAL OUTCOMES OF PERORAL CHOLANGIOPANCREATOSCOPY USING THE 9-FR EYEMAX FOR THE DIAGNOSIS OF PANCREATOBILIARY DISEASE

Haruo Miwa, Kazuki Endo, Ritsuko Oishi, Yuichi Suzuki et autres

Amoebic colitis insufficient to metronidazole monotherapy

Ryosuke Ikeda, Hiroaki Kaneko, Hiroki Sato, Hideyuki Anan et autres

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