Tokio Katakura

Distinct clinical outcomes of positron emission tomography/computed tomography-based subtypes in treatment-naïve Takayasu arteritis

Tokio Katakura, Tsuyoshi Shirai, Yusho Ishii, Hiroko Sato et autres

OBJECTIVE: Positron emission tomography/computed tomography (PET/CT) enables the visualization of vascular inflammation in Takayasu arteritis (TAK). However, the prognostic significance of PET/CT-based arterial involvement remains unclear. This study aimed to classify the distribution patterns of vascular lesions in treatment-naïve TAK using PET/CT …

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Renal Pelvic and Periureter Masses in Cutaneous and Systemic Plasmacytosis

Tokio Katakura, Shiho Yanagawa, Masao Nishiya, Yuki Nakamura et autres

We report a case of cutaneous and systemic plasmacytosis (CSP), with unusually large bilateral renal pelvic and periureteral masses, accompanied by severe renal dysfunction. A 53-year-old man with disseminated reddish-brown plaques developed progressive renal failure over 3 years. Laboratory tests revealed polyclonal …

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Reversal of chronic arterial stenosis with biologic therapy including tocilizumab in Takayasu arteritis

Chisako Kitayama, Tsuyoshi Shirai, Tokio Katakura, Yusho Ishii et autres

Biologic agents have demonstrated efficacy in the treatment of refractory Takayasu arteritis (TAK). Although vascular stenosis is a common manifestation of the chronic phase of TAK, evidence on the effects of biologic therapy on established vascular lesions remains limited. Here, we report …

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Secondary Pulmonary Alveolar Proteinosis Complicated by Hemophagocytic Syndrome in a Patient with Adult-onset Still's disease: A Case-based Review

Tokio Katakura, Tsuyoshi Shirai, Yusho Ishii, Hiroko Sato et autres

Treatment of secondary pulmonary alveolar proteinosis (SPAP) focuses on managing the underlying disease, typically myelodysplastic syndrome. However, immunosuppressive therapy may worsen the condition in autoimmune disease-associated SPAP. We report the case of a 74-year-old woman with hemophagocytic syndrome and adult-onset Still's disease, …

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Positron Emission Tomography in Takayasu Arteritis: A Review Including Patterns of Vascular Involvement Across Modalities and Regions

Tokio Katakura, Tsuyoshi Shirai

Takayasu arteritis (TAK) is a rare, chronic large-vessel vasculitis that predominantly affects the aorta and its major branches. Early and accurate diagnosis remains essential to prevent irreversible vascular damage and organ dysfunction. Positron emission tomography/computed tomography (PET/CT) has emerged as a valuable …

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Clinical Images: Multiple blisters on the upper and lower extremities in granulomatosis with polyangiitis

Tokio Katakura, Tsuyoshi Shirai, Hiroshi Fujii, Kenta Oka et autres

The patient, a 51-year-old woman, was admitted for an evaluation of productive cough and progressive rash on the extremities for three months. Physical examination revealed right scleral and conjunctival injection, right conductive hearing loss, sinus tenderness with epistaxis, coarse crackles in the …

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Refractory skin ulcers and afebrile bacteraemia with Staphylococcus aureus in antimelanoma differentiation-associated gene 5 antibody-positive dermatomyositis: A case report

Tokio Katakura, Tsuyoshi Shirai, Yusho Ishii, Hiroko Sato et autres

Skin ulcers sometimes appear in patients with antimelanoma differentiation-associated gene 5 (MDA5) antibody-positive dermatomyositis (DM) and are usually associated with disease activity. Here, we report a case of a 41-year-old woman with anti-MDA5 antibody-positive DM, who developed refractory skin ulcers during the …

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Eosinophilic Granulomatous Interstitial Nephritis in Eosinophilic Granulomatous Polyangiitis

Machi Kiyohara, Tokio Katakura, Yuki Nakamura, Izaya Nakaya

A 74-year-old woman with bronchial asthma and schizophrenia was admitted to our hospital with leg numbness and eosinophilia.Laboratory tests revealed the following: eosinophils, 11,840/μL; creatinine (Cr), 0.78 mg/dL; urinary protein/Cr ratio, 0.77 g/gCr without hematuria; and urinary β2microglobulin, 83,900 μg/L.Myeloperoxidase and proteinase …

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State-Self-Determining Reinforcement Learning for Adapting to Unknown Environments and Elucidating Higher Brain Functions

Kazuhiro Sakamoto, Tokio Katakura, N. Tamura

The real world is an indefinite environment in which the probability space is not specified in advance. Here, we developed a learning model in which the state space is expanded so that it refers to the arbitrary length of previous states, based …

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Successful management of interstitial lung disease in dermatomyositis complicated by malignancy: a case-based review

Tokio Katakura, Tsuyoshi Shirai, Hiroko Sato, Tomonori Ishii

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Reinforcement Learning Model With Dynamic State Space Tested on Target Search Tasks for Monkeys: Self-Determination of Previous States Based on Experience Saturation and Decision Uniqueness

Tokio Katakura, Mikihiro Yoshida, Haruki Hisano, Hajime Mushiake et autres

The real world is essentially an indefinite environment in which the probability space, i. e., what can happen, cannot be specified in advance. Conventional reinforcement learning models that learn under uncertain conditions are given the state space as prior knowledge. Here, we …

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