Udit Thakur

Steep Repolarization Gradients

Udit Thakur, Jonathan M. Kalman

au (code pays fourni par la source)

A new approach to an old disease: Ageing, arrhythmogenic substrate and the role of risk‐factor modification in atrial fibrillation

Udit Thakur, Jonathan M. Kalman

Atrial fibrillation (AF) prevalence rises sharply with age due to two independent mechanisms. Ageing produces irreversible arrhythmogenic substrate changes through progressive fibrosis, cellular senescence and mitochondrial dysfunction, while modifiable risk factors such as obesity, hypertension, sleep apnoea, diabetes and alcohol use promote …

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SGLT2 inhibitors are associated with reductions in epicardial adipose tissue volume and thickness: a meta-analysis

Shaun Khanna, Elana Kalman, Kaushik Thungathurthi, Udit Thakur et autres

BACKGROUND: Epicardial adipose tissue (EAT), a metabolically active fat depot surrounding the myocardium, is implicated in the pathogenesis of cardiovascular disease. Sodium-glucose co-transporter-2 inhibitors (SGLT2i) have demonstrated cardioprotective effects beyond glucose lowering, including a modification of EAT. We performed a systematic review …

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Progression of persistent atrial fibrillation and impact of ablation: A systematic review and meta-analysis

Udit Thakur, Souvik Kumar Das, Nitesh Nerlekar, Peter M. Kistler et autres

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Circulating metabolomic profile and its association with atrial fibrillation and systemic inflammation

Udit Thakur, William A. Figgett, Devy Deliyanti, Joshua Hawson et autres

Background Atrial fibrillation (AF) is a prevalent arrhythmia associated with chronic inflammation and metabolic dysregulation. Metabolic and inflammatory pathways may influence atrial electrophysiology and structural remodeling, contributing to AF onset and persistence, yet key circulating signatures remain poorly defined. Objective To characterize …

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Short‐Term Procedural Outcomes of Posterior Wall Isolation Using the Affera Pulse Field Ablation System

Udit Thakur, Jasper Junker, Youlin Koh, Sohaib A. Virk et autres

BACKGROUND: Posterior wall isolation (PWI) is often added to pulmonary vein isolation (PVI) for persistent atrial fibrillation (AF) and at redo ablation. Still, procedural performance with the Affera pulsed field ablation (PFA) platform is not well described. METHODS: We retrospectively analyzed consecutive …

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CLaRE: CLIP with Latent Reconstruction Errors for Generated Face Detection

Udit Thakur, M.K. Khan, Meher Changlani, Asen Dotsinski et autres

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The Evolving Treatment and Outcomes of Patients Presenting With STEMI and Cardiogenic Shock—A Regional Experience

Anita Shirwaiker, James Henderson, J McLarty, Udit Thakur et autres

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On the Generalizability of "Competition of Mechanisms: Tracing How Language Models Handle Facts and Counterfactuals"

Asen Dotsinski, Udit Thakur, M.K. Khan, Maria Heuss

We present a reproduction study of "Competition of Mechanisms: Tracing How Language Models Handle Facts and Counterfactuals" (Ortu et al., 2024), which investigates competition of mechanisms in language models between factual recall and counterfactual in-context repetition. Our study successfully reproduces their primary …

Validation of physiological principles of Non-Invasive fractional flow reserve derived from CT coronary angiography

Abdul Rahman Ihdayhid, Harsh V. Thakkar, Michael Michail, Michael Leung et autres

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Cardiology patients are unaware of the benefits of seasonal influenza immunization

Sarah R. Monagle, Ella Spear, Timothy Abrahams, Udit Thakur et autres

Seasonal influenza immunization reduces the risk of cardiovascular events. Patients with established cardiovascular disease (CVD) derive a greater benefit than those without, yet up to 50 % do not take up the immunization. Patient perceptions and beliefs are known to inform immunization …

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Computed tomography coronary angiography assessment of left main coronary artery stenosis severity

Udit Thakur, Jason Nogic, Andrea Comella, Nitesh Nerlekar et autres

Background Angiographic assessment of left main coronary artery (LMCA) stenosis severity can be unreliable. In cases of ambiguity, intravascular ultrasound (IVUS) can be utilised with a minimal lumen area (MLA) of ≥6 ​mm 2 an accepted threshold for safe deferral of revascularization. …

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