Benedikt Kamp

Quantitative Sodium MRI of the Human Patellar Tendon

Rika Möller, Julia Jurisic, Lukas R. Drewes, Alexandra Ljimani et autres

ABSTRACT Sodium MRI can be used in musculoskeletal imaging to assess tissue composition because sodium concentration is related to glycosaminoglycan (GAG) content. In tendinopathy, the GAG content is elevated, resulting in a high signal in sodium MRI. Because biochemical changes typically precede …

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Investigation of Endogenous Renal CEST Contrast and the Influence of Respiratory Motion on a Clinical 3 Tesla MRI : An In Vivo and In Vitro Study

Patrik Jan Gallinnis, Benedikt Kamp, Karl Ludger Radke, Anna‐Katharina Juric et autres

ABSTRACT Purpose The aim is to evaluate the effectiveness of timed breathing in reducing respiratory motion artifacts in renal chemical exchange saturation transfer (CEST) MRI and to assess potential differences in CEST effects between renal compartments. Methods An electro‐pneumatic phantom with a …

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Evaluation of Partial Volume Correction Techniques for Sodium MRI of the Achilles Tendon

Benedikt Kamp, Paula Leja, Thomas Andreas Thiel, Eric Bechler et autres

ABSTRACT Purpose To evaluate partial volume correction (PVC) techniques for sodium MRI of the Achilles tendon in situ and in vivo. Methods Five PVC methods were evaluated including a volume ratio of the proton and sodium segmentations (PSSR), a modified least trimmed …

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MRT-Diagnostik bei Achillessehnenerkrankungen

Philipp Sewerin, Benedikt Kamp, Anja Müller‐Lutz

Zusammenfassung Achillessehnenerkrankungen sind eine häufige Ursache für Schmerzen und Funktionseinschränkungen der unteren Extremität, insbesondere bei sportlich aktiven Patienten oder solchen mit entzündlichen Grunderkrankungen. Die Magnetresonanztomografie (MRT) hat sich als zentrale bildgebende Modalität etabliert, da sie eine differenzierte Beurteilung der Sehnenstruktur, entzündlicher Begleitveränderungen …

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23Na MRI of the patellar tendon: A comparison between healthy volunteers and patients with tendinopathy at 3T.

Benedikt Kamp, Patrik Jan Gallinnis, Armin Michael Nagel, Hans‐Jörg Wittsack et autres

Motivation: Patellar tendinopathy is one of the most common knee pathologies. Tendinopathy changes the biochemical composition of the tendon and 23Na MRI might be able to detect this change in early stages of the disease, as has already been shown in 23Na …

Comparison of twelve‐layer concentric object ( TLCO ) and Line segmentations methods to determine the renal corticomedullary sodium gradient ( CMSG ) with a 3 T MRI

Patrik Jan Gallinnis, Alexandra Ljimani, Yusuf Cabuk, Marie Scheuer et autres

PURPOSE: Na MRI is a functional imaging technique that facilitates measurements of the renal corticomedullary sodium gradient (CMSG). The CMSG can be determined by a region of interest (ROI) in the renal parenchyma along the corticomedullary axis (Line method) or by dividing …

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Unlocking the Secrets of Lumbar Disc Degeneration: Revealing Early Changes using Advanced 23Na MRI

Miriam Frenken, Benedikt Kamp, Anja Müller‐Lutz

Motivation: The global impact of lumbar back pain requires an understanding of degenerative disc disease. Conventional MRI often misses early changes, necessitating a more sensitive technique for accurate detection. Goal(s): To determine the efficacy of 3T-MRI with 23Na in accurately assessing degeneration …

No denoising, no diamonds? - In silico analysis of denoising methods for CEST MR imaging

Karl Ludger Radke, Vibhu Adriaenssens, Benedikt Kamp, Patrik Jan Gallinnis et autres

CEST imaging requires a high SNR to detect low metabolite concentrations, especially at clinical used magnetic field strength (3 Tesla). In recent years, various approaches have been used to denoise CEST data. Our study investigated the performance of different denoising algorithms using …

Sodium MRI of the Lumbar Intervertebral Discs of the Human Spine: An Ex Vivo Study

Benedikt Kamp, Karl Ludger Radke, Marek Knet, Rosanna Strunk et autres

Background Lower back pain affects 75%–85% of people at some point in their lives. The detection of biochemical changes with sodium ( 23 Na) MRI has potential to enable an earlier and more accurate diagnosis. Purpose To measure 23 Na relaxation times …

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Quantitative and Compositional MRI of the Articular Cartilage: A Narrative Review

Domenico Albano, Umberto Viglino, Francesco Esposito, Aldo Rizzo et autres

This review examines the latest advancements in compositional and quantitative cartilage MRI techniques, addressing both their potential and challenges. The integration of these advancements promises to improve disease detection, treatment monitoring, and overall patient care. We want to highlight the pivotal task …

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Standardization of a CT Protocol for Imaging Patients with Suspected COVID-19—A RACOON Project

Andrea Steuwe, Benedikt Kamp, Saif Afat, Alena Akinina et autres

CT protocols that diagnose COVID-19 vary in regard to the associated radiation exposure and the desired image quality (IQ). This study aims to evaluate CT protocols of hospitals participating in the RACOON (Radiological Cooperative Network) project, consolidating CT protocols to provide recommendations …

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Deep Learning-Based Denoising of CEST MR Data: A Feasibility Study on Applying Synthetic Phantoms in Medical Imaging

Karl Ludger Radke, Benedikt Kamp, Vibhu Adriaenssens, Julia Stabinska et autres

Chemical Exchange Saturation Transfer (CEST) magnetic resonance imaging (MRI) provides a novel method for analyzing biomolecule concentrations in tissues without exogenous contrast agents. Despite its potential, achieving a high signal-to-noise ratio (SNR) is imperative for detecting small CEST effects. Traditional metrics such …

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