Kevin R. Barker

Incidence of colonization and infection with carbapenemase-producing Enterobacterales in Toronto and Peel Region, Ontario, 2007–2024

Angel Xinliu Li, Maxime Lefebvre, Zoë Zhong, Huda Almohri et autres

Background: Carbapenemase-producing Enterobacterales (CPE) are an urgent public health threat. Monitoring changes in the epidemiology of CPE is critical to the development of action plans against antimicrobial resistance. Methods: The Toronto Invasive Bacterial Diseases Network (TIBDN) has conducted population-based surveillance for CPE …

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Invasive Group A Streptococcal Disease in Persons Experiencing Postpandemic Homelessness in Canada

Caroline Kassee, Halima Dabaja‐Younis, Lucie Richard, Alyssa Golden et autres

Importance: Both invasive group A streptococcal (iGAS) infections and the number of persons experiencing homelessness (PEH) are increasing. Protection of PEH from the burden of iGAS infections requires understanding of its epidemiology. Objective: To assess whether the resurgence of iGAS infections after …

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Dépistage amélioré de la tuberculose chez les immigrants du sud du Nouveau-Brunswick : une étude pilote transversale

Isdore Chola Shamputa, Heather K. MacKenzie, Denis A. Gaudet, Kevin R. Barker et autres

Contexte : En 2021, environ 77 % des cas de tuberculose (TB) active au Canada concernaient des personnes nées à l'étranger.Moins de 3 % des cas de TB au Canada sont détectés lors des examens médicaux effectués avant l'arrivée au Canada par …

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Invasive Group A Streptococcal Infection in Children, 1992-2023

Halima Dabaja-Younis, Christopher E. Kandel, Karen Green, Jennie Johnstone et autres

Importance: The resurgence of invasive group A streptococcal (iGAS) infections and progress in GAS vaccine development emphasize the importance of understanding current trends in the epidemiology of iGAS. Objective: To describe the epidemiology of pediatric iGAS over a 32-year period. Design, Setting, …

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P-643. Incidence and Clinical Characteristics of Invasive Group A Streptococcal Infections in Underhoused Adults in Toronto, Canada

Caroline Kassee, Halima Dabaja Younis, Zoë Zhong, Vanessa G Allen et autres

Abstract Background Post-pandemic increases of invasive group A streptococcal disease (iGAS) have been reported in many areas of the world; increased risk associated with illicit intravenous (IV) drug use has also been identified. Methods Since 1995, the Toronto Invasive Bacterial Diseases Network …

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P-1290. Invasive group A streptococcal infection in children in Toronto, Canada

Halima Dabaja Younis, Jennie Johnstone, Zoë Zhong, Caroline Kassee et autres

Abstract Background Rising cases of invasive group A streptococcus (iGAS) in children have been reported globally. We assessed the epidemiology of pediatric iGAS over three decades. The annual incidence of invasive GAS infections in children in Toronto and Peel Region during the …

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The IR Biotyper as a tool for typing organisms of significance for hospital epidemiology- A subject review

Esraa Al-Fraihat, Kevin R. Barker, Manal Tadros

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Evaluation of the utility and cost of secondary confirmatory testing for Neisseria gonorrhoeae identification from culture

Ellen G. Avery, Joseph John Zeppa, Donald Brody Duncan, Kevin R. Barker et autres

Current guideline recommends the use of two identification methods for Neisseria gonorrhoeae. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF) is now used for primary identification and may be sufficient for definitive identification of N. gonorrhoeae. The performance of three secondary tests (BactiCard, …

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When the Trojan horse is unable to reach inside the city: investigation of the mechanism of resistance behind the first reported cefiderocol-resistant E. coli in Canada

Kevin R. Barker, Gabriel W. Rebick, Ken Fakharuddin, Clayton A. MacDonald et autres

ABSTRACT Gram-negative metallo-β-lactamase-producing bacteria can be extremely problematic, especially when found to be extensively drug-resistant (XDR). Cefiderocol is a novel antimicrobial that has been shown to overcome most carbapenemases, with very rare resistance reported to date. Within our institution, two multidrug-resistant and …

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Reply to “A failure of Fourier transform infrared spectroscopy to type Burkholderia isolates from chronically infected patients with cystic fibrosis”

Kevin R. Barker, Manal Tadros

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Detection of SARS-CoV-2 from combined nasal/rectal swabs

Adriana M. Airo, Kevin R. Barker, Matthew Paul Muller, Linda R. Taggart et autres

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89. On-going impact of the SARS-CoV-2 pandemic on the evolution of carbapenemase-producing Enterobacterales in Ontario, Canada

Mohammad Mozafarihashjin, Alainna Juliette Jamal, Christopher E. Kandel, Philipp P. Kohler et autres

Abstract Background The spread of carbapenemase-producing Enterobacterales (CPE) is global threat. Numerous outbreaks of CPE have been reported during the COVID-19 pandemic. We describe the impact of of the SARS-CoV-2 pandemic on the emergence of CPE in south-central Ontario, Canada. Incidence of …

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