Kenneth E. Wilson

Using synchrotron FTIR spectromicroscopy to assess physiological and metabolic changes in photosynthetic mutants of Chlamydomonas reinhardtii

Kira L. Goff, Kenneth E. Wilson, T. H. Ellis

We utilized synchrotron Fourier-transform infrared spectromicroscopy to study photosynthetic mutants of the unicellular green algae Chlamydomonas reinhardtii. We were able to observe direct and knock-on effects of multiple mutations on the physiology and metabolism of individual living cells, and cleanly differentiate the …

ca, Nigéria (code pays fourni par la source)

The ARP2/3 complex, acting cooperatively with Class I formins, modulates penetration resistance in Arabidopsis against powdery mildew invasion

Li Qin, Lìjiāng Liú, J. C. Tu, Guogen Yang et autres

The actin cytoskeleton regulates an array of diverse cellular activities that support the establishment of plant-microbe interactions and plays a critical role in the execution of plant immunity. However, molecular and cellular mechanisms regulating the assembly and rearrangement of actin filaments (AFs) …

ca, cn, us (code pays fourni par la source)

Synchrotron FTIR spectromicroscopy as a tool for studying populations and individual living cells of green algae

Kira L. Goff, T. H. Ellis, Kenneth E. Wilson

Fourier transform infrared (FTIR) spectromicroscopy was used to study individual living cells of three closely-related species of the green algal genus Chlamydomonas. Three types of spectral variation were observed between individual cells within a single culture, as well as between different cultures: …

ca (code pays fourni par la source)

Synchrotron FTIR as a tool for studying populations and individual living cells of green algae

Kira L. Goff, Thomas Sayers Ellis, Kenneth E. Wilson

Abstract Fourier transform infrared (FTIR) spectromicroscopy was used to study individual living cells of three closely-related species of the green algae Chlamydomonas . This study differentiated these three species based on differences in lipid and protein profiles, as well explored sources of …

ca (code pays fourni par la source)

Discovery, Isolation, and Structure Elucidation of Dretamycin

Kenneth E. Wilson, Scott K. Smith, Rosemarie Kelly, Prakash Masurekar et autres

The Candida albicans fitness test is a whole cell screening platform that utilizes a mixed-pool of C. albicans mutants, each of which carries a heterozygous deletion of a particular gene. In the presence of an antifungal inhibitor, a subset of these mutants …

us, ca (code pays fourni par la source)

Evaluation of biologically mediated changes in oil sands naphthenic acid composition by C hlamydomonas reinhardtii using negative‐ion electrospray orbitrap mass spectrometry

Kira L. Goff, Kerry M. Peru, Kenneth E. Wilson, John V. Headley

Industrial activity associated with oil-sands extraction in Canada's Athabasca region produces a variety of contaminants of concern, including naphthenic acid fraction components (NAFCs). NAFCs are a complex mixture of organic compounds that are poorly understood both in terms of their chemical composition …

ca (code pays fourni par la source)

Metabolic Transformations of Alkyl Parabens in the Skin: Specific Esterase Inhibition Study

Geoffrey C. Ford, Alan B. McEwen, Kenneth E. Wilson, Stuart Wood

The skin plays a vital role in protecting the body from invading pathogens and provides a barrier against the absorption of hazardous chemicals. One of the key physical properties that enable xenobiotics to be absorbed in the skin, lipophilicity, also presents an …

gb (code pays fourni par la source)

Assessment of the effects of oil sands naphthenic acids on the growth and morphology of Chlamydomonas reinhardtii using microscopic and spectromicroscopic techniques

Kira L. Goff, John V. Headley, John R. Lawrence, Kenneth E. Wilson

ca (code pays fourni par la source)

Effect of pH on neutral lipid and biomass accumulation in microalgal strains native to the Canadian prairies and the Athabasca oil sands

Blair P. Skrupski, Kenneth E. Wilson, Kira L. Goff, Jitao Zou

ca (code pays fourni par la source)

The PSBP2 protein of Chlamydomonas reinhardtii is required for singlet oxygen-dependent signaling

Pawel Brzezowski, Kenneth E. Wilson, Gordon R. Gray

ca (code pays fourni par la source)

Broadening the Spectrum of β-Lactam Antibiotics through Inhibition of Signal Peptidase Type I

Alex G. Therien, Joann Huber, Kenneth E. Wilson, Patrick Beaulieu et autres

The resistance of methicillin-resistant Staphylococcus aureus (MRSA) to all β-lactam classes limits treatment options for serious infections involving this organism. Our goal is to discover new agents that restore the activity of β-lactams against MRSA, an approach that has led to the …

ca, us (code pays fourni par la source)

Mixotrophic and photoautotrophic cultivation of 14 microalgae isolates from Saskatchewan, Canada: potential applications for wastewater remediation for biofuel production

Kyoung C. Park, Crystal G. Whitney, Jesse McNichol, Kathryn E. Dickinson et autres

ca (code pays fourni par la source)