Christy Nguyen

MON-190 T Cells Are Necessary For The Development Of Reproductive Impairments In A Letrozole-induced Mouse Model Of Polycystic Ovary Syndrome

Naveena Ujagar, Leandro M. Vélez, Gabriela De Robles, Christy Nguyen et autres

Abstract Disclosure: N. Ujagar: None. G. De Robles: None. C. Nguyen: None. K.D. Wiggins: None. Z. Del Mundo: None. J. Cassin: None. J. Kim: None. N. Naidu: None. J.A. Ayala Angulo: None. B. Babaev: None. R.A. Ross: None. A.S. Kauffman: None. V.G. …

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MON-586 Cd1a-mediated Inflammation Contributes To T2d Pathology And Metabolic Homeostasis In Dio Mouse Model

Julio A Ayala Angulo, Miranda Louise Lopez, Kiara Dominique Wiggins, Christy Nguyen et autres

Abstract Disclosure: J.A. Ayala Angulo: None. M.L. Lopez: None. K.D. Wiggins: None. C. Nguyen: None. Z. Del Mundo: None. N. Ujagar: None. G. De Robles: None. G. Pacheco Sanchez: None. J. Arriola: None. H. Aichlmayr: None. H. Choi: None. J. Ross: None. …

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Systems Genetics Cytokine Screen Identifies T cells as Necessary for Letrozole-Induced LH Elevation in a PMOS-like Mouse Model

Naveena Ujagar, Leandro M. Vélez, Christy Nguyen, Kiara Wiggins et autres

Abstract Polycystic ovary syndrome (PMOS) is a complex reproductive disorder with clear genetic susceptibilities that impact the heterogeneous clinical presentation of symptoms and severity through unknown mechanisms. Chronic inflammation is linked to PMOS, but a clear cause-and-effect relationship between immune mediators and …

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7226 Leveraging Inter-Individual Transcriptional Correlation Structure To Infer Discrete Signaling Mechanisms Across Metabolic Tissues

Mingqi Zhou, Ian Tamburini, Cassandra Van, Jeffrey Molendijk et autres

Abstract Disclosure: M. Zhou: None. I. Tamburini: None. C. Van: None. J. Molendijk: None. L.M. Velez: None. C. Nguyen: None. R. Yeo: None. C. Filho: None. A.L. Hevener: None. J. Justice: None. L.M. Sparks: None. E.E. Kershaw: None. D. Nicholas: None. M. …

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9284 Leveraging Inter-Individual Transcriptional Correlation Structure To Infer Discrete Signaling Mechanisms Across Metabolic Tissues

Mingqi Zhou, Ian Tamburini, Cassandra Van, Jeffrey Molendijk et autres

Abstract Disclosure: M. Zhou: None. I. Tamburini: None. C. Van: None. J. Molendijk: None. L.M. Velez: None. C. Nguyen: None. R. Yeo: None. C. Filho: None. A.L. Hevener: None. J. Justice: None. L.M. Sparks: None. E.E. Kershaw: None. D. Nicholas: None. M. …

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7975 TLR4 Signaling Modulates Reproductive and Metabolic Outcomes in a Mouse Model of Polycystic Ovary Syndrome

Kiara Dominique Wiggins, Zena Del Mundo, Julio A Ayala Angulo, Miranda Lopez et autres

Abstract Disclosure: K.D. Wiggins: None. Z. Del Mundo: None. J.A. Ayala Angulo: None. M. Lopez: None. C. Garcia: None. C. Nguyen: None. J. De La Torre: None. A. Saba: None. D. Trinh: None. D. Nicholas: None. Polycystic Ovarian Syndrome (PCOS), characterized by …

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8603 Sex Steroids Have Opposing Impacts on Female Gonadotrope Metabolism and LH Secretion via GLUT1

Christopher Garcia, Christy Nguyen, Sizhe Wang, Davina Trinh et autres

Abstract Disclosure: C. Garcia: None. C. Nguyen: None. S. Wang: None. D. Trinh: None. U. Le: None. R. Kapadia: None. J. De La Torre: None. C.K. De La Cruz: None. D. Nicholas: None. Gonadotropes of the anterior pituitary regulate reproductive hormone synthesis …

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8258 Haptoglobin-related protein (HPR) new role as insulin secretion enhancer

Carlos H Viesi, Ian Tamburini, Hosung Bae, Erwin Ilegems et autres

Abstract Disclosure: C. Viesi: None. Type 2 Diabetes (T2D) affects over 530 million people around the globe. Insulin resistance, encompassing tissues such as muscle, adipose, and liver, is the initial step hallmarked by hyperinsulinemia. Coupled with β-cell failure, these coordinated responses progress …

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A faster escape does not enhance survival in zebrafish larvae

Arjun Nair, Christy Nguyen, Matthew J. McHenry

An escape response is a rapid manoeuvre used by prey to evade predators. Performing this manoeuvre at greater speed, in a favourable direction, or from a longer distance have been hypothesized to enhance the survival of prey, but these ideas are difficult …

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Supplementary material from "A faster escape does not enhance survival in zebrafish larvae"

Arjun Nair, Christy Nguyen, Matthew J. McHenry

An escape response is a rapid manoeuvre used by prey to evade predators. Performing this manoeuvre at greater speed, in a favourable direction, or from a longer distance have been hypothesized to enhance the survival of prey, but these ideas are difficult …

Data from: A faster escape does not enhance survival in zebrafish larvae

Nair Arjun, Christy Nguyen, Matthew J. McHenry

An escape response is a rapid manoeuvre used by prey to evade predators. Performing this manoeuvre at greater speed, in a favourable direction, or from a longer distance have been hypothesized to enhance the survival of prey, but these ideas are difficult …