Nigel CK Tan

Frequency of anti‐neural antibodies and autoimmune epilepsy in focal epilepsy of unknown etiology: An observational study in a Singaporean cohort

Seong Jin Park, Jeanne May May Tan, Xuejuan Peng, Patricia Yut Wan Wong et autres

OBJECTIVE: Autoimmune epilepsy (AES) is increasingly recognized as a condition in patients with epilepsy of unknown etiology. Early immunotherapy improves outcomes; however, data on its prevalence and the frequency of anti-neural/neuronal antibodies in Asian populations remain scarce. Herein, we aim to (1) …

sg (code pays fourni par la source)

Bridging technology and pedagogy: evaluation of an interprofessional course on technology-enhanced learning for health professions educators

Jason Wen Yau Lee, Nigel CK Tan, Fernando Bello

Background: The proliferation of educational technologies presents both opportunities and challenges for health professions educators. A prior institutional needs assessment found that educators across all professions struggle to adopt these technologies, as they must navigate not only technical requirements but also the …

sg, gb (code pays fourni par la source)

Late onset epilepsy of unknown etiology in Singapore: Clinical features and association with mild cognitive impairment

Jia Yi Shen, Zhibin Tan, Rachel Siew, S H Lim et autres

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Assessment of Large Language Models in Clinical Reasoning: A Novel Benchmarking Study

Liam G. McCoy, Rajiv Swamy, Nidhish Sagar, Minjia Wang et autres

ca, il, us, au, sg (code pays fourni par la source)

How patients experience nurse-doctor collaborative care at specialist clinics: A qualitative study

Yang Yann Foo, Xiaohui Xin, Qianhui Cheng, Hwee Kuan Ong et autres

INTRODUCTION: Patient experience of interprofessional collaboration in primary care has been well-studied but not in specialist clinics. Our qualitative study aimed to understand patients' experience of a nurse-doctor collaboration at three specialist clinics (Epilepsy Clinic, Neuroimmunology Clinic, and Persistent Concussion Clinic) in …

sg, au (code pays fourni par la source)

Do Language Models Think Like Doctors?

Liam G. McCoy, Rajiv Swamy, Nidhish Sagar, Stephen Bacchi et autres

Abstract Background While large language models (LLMs) are being increasingly deployed for clinical decision support, existing evaluation methods like medical licensing exams fail to capture critical aspects of clinical reasoning including reasoning in dynamic clinical circumstances. Script Concordance Testing (SCT), a decades-old …

us, au, sg, il (code pays fourni par la source)

Suboptimal seizure control is associated with increased risk of MCI among Adult Patients with Epilepsy

Jia Yi Shen, Chirin Soh, Rachel Wan En Siew, Seyed Ehsan Saffari et autres

BACKGROUND: Epilepsy is associated with increased risk for dementia, which adversely impacts the quality of life for patients and their families. Mild cognitive impairment (MCI) is the prodromal stage of dementia offering an important window for intervention. However, the epilepsy related risk …

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Novel Biallelic Synonymous Exonic Variant in VPS13A Affecting mRNA Splicing

Rebecca Hui Min Hoe, Yi Zhao, Helen Lisa Ong, Karine Su Shan Tay et autres

Objectives: . We identified a novel synonymous exonic variant leading to abnormal mRNA splicing in a patient with chorea-acanthocytosis. Methods: , mRNA splicing analysis, and Western blot for chorein were performed. Results: (NM_033305.3): c.5157C>T; p.Gly1719 = was identified; this was previously classified …

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PP080 Topic: AS09–Global Health/Resource Limited Setting/Health Inequalities/Impact of Global Warming/Other: DEMOGRAPHICS AND OUTCOMES OF CHILDREN ADMITTED TO THE INTENSIVE CARE UNIT (ICU) IN A REGIONAL HOSPITAL IN NAMIBIA OVER TWELVE MONTHS.

Chris Terblanche, M. Shikongo, Houessinon Festus, T.-N. Pea et autres

Aims & Objectives: There is little published data showcasing demographics and ICU outcomes of paediatric admissions (<16 years old) in Africa. We reviewed paediatric ICU admissions at Intermediate Hospital Oshakati (IHO) to recognise common conditions, identify where clinical guidelines can be developed, …

gb, au (code pays fourni par la source)

Large-format additive manufacturing of polymers: a review of fabrication processes, materials, and design

Guo Dong Goh, Kin Keong Wong, Nigel CK Tan, Hang Li Seet et autres

ABSTRACTLarge-format 3D printing for polymers enables cost-effective mass customisation and production of structurally robust, large-scale components for industries like aerospace and automotive. This review analyses additive manufacturing scalability, including throughput, volume, and essential criteria for 3D printing techniques. Challenges in large-scale polymer …

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Evaluation of prognostic scores for status epilepticus in the neurology ICU: A retrospective study

Jia Yi Shen, Seyed Ehsan Saffari, Linda Yong, Nigel CK Tan et autres

sg (code pays fourni par la source)

How community and organizational culture interact and affect senior clinical educator identity

Wai Ching Lee, Nigel CK Tan, Kevin S.Y. Tan, Xianguang Joel Yee et autres

PURPOSE: The development of Educator Identity has a significant impact on well-being, motivation, productivity, and the quality of teaching. Previous research has shown that conflicting responsibilities and a challenging work environment could negatively affect the development of Clinical Educator Identity within an …

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