Justinas Teišerskas

Preemptive Morphine During Therapeutic Hypothermia After Neonatal Encephalopathy: A Secondary Analysis

Natasha Liow, Paolo Montaldo, Peter Lally, Justinas Teišerskas et autres

Although therapeutic hypothermia (TH) improves outcomes after neonatal encephalopathy (NE), the safety and efficacy of preemptive opioid sedation during cooling therapy is unclear. We performed a secondary analysis of the data from a large multicountry prospective observational study (Magnetic Resonance Biomarkers in …

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Associations between Red Blood Cell Transfusions and Necrotizing Enterocolitis in Very Low Birth Weight Infants: Ten-Year Data of a Tertiary Neonatal Unit

Justinas Teišerskas, Rūta Bartašienė, Rasa Tamelienė

Background and Objective: Necrotizing enterocolitis (NEC) remains an important cause of mortality in preterm neonates. There are many risk factors for NEC; however, probably the most controversial one is red blood cell transfusions (RBCT). The data concerning the link between NEC and …

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Therapeutic hypothermia for mild neonatal encephalopathy: a systematic review and meta-analysis

Ujwal Kariholu, Paolo Montaldo, Theodora Markati, Peter Lally et autres

OBJECTIVES: To examine if therapeutic hypothermia reduces the composite outcome of death, moderate or severe disability at 18 months or more after mild neonatal encephalopathy (NE). DATA SOURCE: MEDLINE, Cochrane database, Scopus and ISI Web of Knowledge databases, using 'hypoxic ischaemic encephalopathy', …

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Therapeutic hypothermia initiated within 6 hours of birth is associated with reduced brain injury on MR biomarkers in mild hypoxic-ischaemic encephalopathy: a non-randomised cohort study

Paolo Montaldo, Peter Lally, Vânia Oliveira, Ravi Shankar Swamy et autres

OBJECTIVE: To examine the effect of therapeutic hypothermia on MR biomarkers and neurodevelopmental outcomes in babies with mild hypoxic-ischaemic encephalopathy (HIE). DESIGN: Non-randomised cohort study. SETTING: Eight tertiary neonatal units in the UK and the USA. PATIENTS: 47 babies with mild HIE …

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Prognostic Accuracy of Heart Rate Variability Analysis in Neonatal Encephalopathy: A Systematic Review

Vânia Oliveira, Rui Martins, Natasha Liow, Justinas Teišerskas et autres

BACKGROUND: Heart rate variability analysis offers real-time quantification of autonomic disturbance after perinatal asphyxia, and may therefore aid in disease stratification and prognostication after neonatal encephalopathy (NE). OBJECTIVE: To systematically review the existing literature on the accuracy of early heart rate variability …

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Naujagimių kraujagyslinių kateterių kolonizacijos ypatumai ir ryšys su infekcija LSMUL Kauno klinikose

Justinas Teišerskas

Neonatal intravascular catheter colonisation and association with infection in LUHS hospital Kauno Klinikos

Justinas Teišerskas

Tyrimo tikslas. Apibūdinti 2013 bei 2015-2016 metais Lietuvos sveikatos mokslų universiteto ligoninės Kauno klinikų (LSMUL KK) Neonatologijos klinikoje buvusius su kateteriu susijusios naujagimių infekcijos atvejus. Tyrimo uždaviniai: nustatyti su kateteriu susijusios naujagimių infekcijos tipų dažnį; įvertinti kateterių pasėlių diagnostinę vertę; nustatyti dažniausiai …

Rhamnose-Inducible Gene Expression in Listeria monocytogenes

Lars Fieseler, Sibylle Schmitter, Justinas Teišerskas, Martin J. Loessner

Acid production from rhamnose is a characteristic phenotype of Listeria monocytogenes. We report the identification of the rhamnose transport and utilization operon located at lmo2846 to lmo2851, including the rhamnose-dependent promoter P(rha). Expression of reporter genes under control of P(rha) on a …

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Characterization of Escherichia coli dinJ-yafQ Toxin-Antitoxin System Using Insights from Mutagenesis Data

Julija Armalytė, Milda Jurėnaitė, Gina Beinoravičiūtė, Justinas Teišerskas et autres

Escherichia coli dinJ-yafQ operon codes for a functional toxin-antitoxin (TA) system. YafQ toxin is an RNase which, upon overproduction, specifically inhibits the translation process by cleaving cellular mRNA at specific sequences. DinJ is an antitoxin and counteracts YafQ-mediated toxicity by forming a …

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