Im-Joung La

Bioactive compounds and multifaceted health benefits of noni (Morinda citrifolia L.) and fermented noni: a review

Ji‐Hyun Im, Xiaolu Fu, Sun‐Il Choi, Jae-Yeon Lee et autres

Fermented Noni Polysaccharides and Immune-Related Biomarkers in Adults with Recurrent URTIs: A Randomized, Double-Blind, Placebo-Controlled Trial

Seon-mi Shin, Seong-Hwan Park, Seon-Gyu Bae, Eun-Young Park et autres

Background: Fermented polysaccharides derived from Morinda citrifolia (noni) have been suggested to modulate innate immune responses, but clinical evidence remains limited. Objectives: This randomized, double-blind, placebo-controlled trial evaluated the effects of fermented noni polysaccharides on natural killer (NK) cell activity and immune-related …

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Combined Immune-Stimulatory Effects of HemoHIM and Hwaljingigo Treatment in RAW 264.7 Macrophages

Min-Hye Kim, Ji-Hyun Im, Xiaolu Fu, June-Seok Lim et autres

The immune system plays a pivotal role in the maintenance of homeostasis and protection from pathogens. With increasing public interest in immune health, functional foods and herbal formulations are gaining attention as potential immunomodulators. Therefore, we aimed to investigate the combined immune-enhancing …

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Shotgun Metagenomic Analysis of Gut Microbiota and Antibiotic Resistance Genes in a High-Fat Diet Mouse Model Treated with Heat-Killed Lactiplantibacillus plantarum beLP1

Ranjith Kumar Manoharan, Hyun-Dong Shin, Yura Lee, Sunhwa Baek et autres

The gut microbiota is a central regulator of metabolic function, and its disruption by a high-fat diet (HFD) is strongly linked to obesity and metabolic impairment. This study evaluated the potential of heat-killed Lactiplantibacillus plantarum beLP1 (beLP1®) in alleviating HFD-induced metabolic and …

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Comprehensive Evaluation of the Bioactive Components and Multifunctional Biological Activities of Hwaljingigo

Ji-Hyun Im, Im-Joung La, Xiaolu Fu, June-Seok Lim et autres

Ji-Hyun Im, Im-Joung La, Xiaolu Fu, June-Seok Lim, Min-Hye Kim, Yeon-Seok Seong, Tae-Woong Song, Sun-Il Choi, DoSang Lee, Rae-Kyo Jeong, Yeon-Hee Jeon, and Ok-Hwan Lee. Journal of the Korean Society of Food Science and Nutrition 2026;55:283-94. https://doi.org/10.3746/jkfn.2026.55.3.283

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Synergistic Anticancer Effects of Fermented Noni Extract Combined with 5-Fluorouracil, Doxorubicin, and Vincristine on A549, MCF-7, and SH-SY5Y Cell Models

June-Seok Lim, Ji‐Hyun Im, Xiaolu Fu, Min-Hye Kim et autres

Although chemotherapy is a primary approach for cancer treatment, its efficacy is often compromised by the development of drug resistance and occurrence of serious side effects. To improve chemotherapy outcomes, this study aimed to evaluate the synergistic anticancer effects of fermented noni …

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Assessment of 12 Ginsenosides and the Antioxidant Activity of Red Ginseng Sprout Extracts

Geon Oh, Do-Sang Lee, Seon Woo Park, Ji-Hyun Im et autres

This study aimed to establish a high-performance liquid chromatography coupled with photodiode array detection (HPLC–PDA) method for the simultaneous quantification of 12 ginsenosides in red ginseng sprout (RGS) extract produced from smart-farm-cultivated ginseng sprouts and to evaluate its antioxidant activity as part …

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Analysis of the Bioactive Compounds and Physiological Activities of Commonly Consumed Noni Juice in Republic of Korea

Xiaolu Fu, Min-Hye Kim, Geon Oh, Ji‐Hyun Im et autres

L.) juice is increasingly recognized for its potential health-promoting properties. In this research, the bioactive compounds and physiological effects of commercial noni juice products in Korea were assessed. Noni juice was found to contain high levels of total phenolics (6.39 ± 1.45 …

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Assessment of Bioactive Compounds and Antioxidant Activity of Barley Sprouts

Geon Oh, Im-Joung La, Do-Sang Lee, Ji‐Hyun Im et autres

Barley sprouts, rich in bioactive compounds, have gained attention as functional food ingredients because of their antioxidant potential. This study evaluated their bioactive composition and antioxidant capacity, focusing on the saponarin, chlorophyll, policosanol, total polyphenol (TP), and total flavonoid (TF) contents. The …

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Profiling of phytochemicals in Adenophora triphylla using LC-Q-TOF/MS-based untargeted metabolomics

Yoonjeong Kim, Jiye Pyeon, Yeong-Eun Yu, Chul-Jong Jung et autres

This study investigated the metabolic changes upon hydrothermal extraction of A. triphylla root, employing untargeted metabolomics analysis.

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Fermented red ginseng extract improves sarcopenia-related muscle atrophy in old mice through regulation of muscle protein metabolism

Geon Oh, Xiao Men, Im-Joung La, Xionggao Han et autres

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Ameliorative Effects of Fermented Red Ginseng Extract on Muscle Atrophy in Dexamethasone-Induced C2C12 Cell And Hind Limb-Immobilized C57BL/6J Mice

Xiao Men, Xionggao Han, Im-Joung La, Se-Jeong Lee et autres

Fermented red ginseng (FRG) enhances the bioactivity and bioavailability of ginsenosides, which possess various immunomodulatory, antiaging, anti-obesity, and antidiabetic properties. However, the effects of FRG extract on muscle atrophy and the underlying molecular mechanisms remain unclear. This study aimed to elucidate the …

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