Lea Rose Dougherty

Reward-Related Neural Substrates of Irritability: A Task-Based fMRI Study of Early Childhood

Ruiyu Yang, Qiongru Yu, Erin O. Peterson, Lea Rose Dougherty et autres

OBJECTIVE: Irritability, conceptualized as elevated proneness to anger, is a transdiagnostic feature and robust predictor of multiple psychological disorders. Identifying neurophenotypes of irritability in early childhood is critical to inform timely intervention, as irritability persisting into school age is associated with increased …

us (code pays fourni par la source)

Inhibitory control-related neural pathways of early adversity to internalizing problems in preadolescence

Krupali R. Patel, Brígida Hernández, Alyssa J. Parker, Lea Rose Dougherty et autres

OBJECTIVE: Exposure to early life adversity has long-reaching effects on the psychopathology of adolescents. However, some individuals exposed to early life stressors, such as threat and deprivation, do not later present with symptoms. Previous research suggests that neural mechanisms may play a …

us (code pays fourni par la source)

The relationship between youth irritability and neural circuitry related to emotion regulation

Anna D. Stumps, Leah D. Church, Nadia Bounoua, Lea Rose Dougherty et autres

us (code pays fourni par la source)

Depression in early childhood.

Lea Rose Dougherty, Leah K. Sorcher, Grace Messina, Mina Hughes

Early Interventions for Young Children High in Behavioral Inhibition: Effects on Early Childhood Irritability

Hong N.T. Bui, Danielle R. Novick, Emma Chad‐Friedman, Simone Chad-Friedman et autres

Irritability, or the tendency to experience negative affect and temper outbursts, is commonly endorsed in youth with anxiety disorders. Irritability and anxiety predict one another in cross-sectional and longitudinal studies and share neural circuitry, suggesting potential benefit from shared treatment components. However, …

us (code pays fourni par la source)

Structural Brain Correlates of Childhood Inhibited Temperament: An ENIGMA-Anxiety Mega-Analysis

Janna Marie Bas‐Hoogendam, Rachel A. Bernstein, Brenda E. Benson, Samuel Frank et autres

OBJECTIVE: Childhood inhibited temperament (cIT) is associated with an increased risk for developing internalizing psychopathology. Neurobiological characteristics identified by structural magnetic resonance imaging (MRI) may elucidate the neural substrates for cIT, but studies are scarce and often focus on particular regions of …

nl, us, br, ca, cl, gb, it, hk, Afrique du Sud (code pays fourni par la source)

Dimensional foundations toward a novel nosology addressing comorbidity: Preadolescent syndrome profiles

Johanna C. Walker, Alyssa J. Parker, Krupali R Patel, Lea Rose Dougherty et autres

OBJECTIVE: Traditional categorical systems for diagnosing psychopathological symptoms, such as the DSM-5, face limitations including high comorbidity rates and insufficient support for transdiagnostic treatment protocols. Dimensional, person-centered approaches can address these limitations by focusing on cross-cutting psychiatric symptoms. METHOD: This study leverages …

us (code pays fourni par la source)

Deep learning identification of reward-related neural substrates of preadolescent irritability: A novel 3D CNN application for fMRI

Johanna C. Walker, Conner Swineford, Krupali R Patel, Lea Rose Dougherty et autres

The recent emergence of deep learning methods, particularly convolutional neural networks (CNNs), applied to fMRI data presents a promising avenue in psychiatry research, offering advantages over traditional analyses by requiring minimal assumptions and enabling detection of higher-level patterns and intricate, nonlinear relationships …

us (code pays fourni par la source)

Sleep Difficulties Across Preschool Age: Associations with Parenting and Parental Psychopathology

Alyssa M. Rodriguez, Akira J. Isaac, Lea Rose Dougherty, Daniel N. Klein et autres

us (code pays fourni par la source)

Risk and resilience profiles and their transition pathways in the ABCD Study – CORRIGENDUM

Ruiyu Yang, Sabrena Tuy, Lea Rose Dougherty, Jillian Lee Wiggins

Hippocampal subregion volumes and preadolescent depression risk in the ABCD sample

Alyssa J. Parker, Leah K. Sorcher, Olivia P. Cutshaw, Morgan Botdorf et autres

The hippocampus is central in the pathophysiology of depression. Subregions of the hippocampus (head, body, tail) have been implicated in adult depression, though research examining depression and hippocampal subregions in youth has been limited. This study aimed to examine associations between preadolescent …

us (code pays fourni par la source)

The Predictive Value of Preadolescent Suicidal Ideation Reporter Discrepancies in the ABCD Study

Alyssa J. Parker, Peyton Brock, Mina Hughes, Olivia P. Cutshaw et autres

us (code pays fourni par la source)