Author Correction: The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis
Trevor P. Fidler, Chenyi Xue, Mustafa Yalçınkaya, Brian Hardaway et autres
us, de, nl, se (code pays fourni par la source)
1 citation
Nature
Larry L. Luchsinger
Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.
56Publications signalées
3914Citations signalées
2Affiliations récentes
Les institutions déclarées
Les domaines associés
SARS-CoV-2 and COVID-19 ResearchHematopoietic Stem Cell TransplantationCOVID-19 Clinical Research StudiesSARS-CoV-2 detection and testingAcute Myeloid Leukemia Research
Les publications récentes
Inflammasome adaptor protein ASC is a mechanistic checkpoint in IL-1β maturation
Giti Saha, Pratibha Anchi, Richard Wang, Alyssa Biondo et autres
Inflammasome activation triggers caspase-1-dependent maturation of pro-interleukin-1β (pro-IL-1β) in an apoptosis-associated speck-like protein containing a CARD (ASC)-dependent manner, yet the mechanism by which pro-IL-1β is physically recruited to the ASC signaling platform has remained undefined. Here, we identify the ASC linker domain …
us, ae (code pays fourni par la source)
0 citations
Proceedings of the National Academy of Sciences
“Connexin” the dots in hematopoietic stem cell potential
Efficacy and safety of venetoclax combination therapy for relapsed/ refractory acute myeloid leukemia: a systematic review
us (code pays fourni par la source)
0 citations
Blood
Mitofusin agonists improve the long-term repopulating activity of human cord blood HSCs after ex vivo culture
Alyssa Biondo, Gabriela de Toledo Passos Candelaria, Daniel K. Jin, Emily Pei-Ying Lin et autres
Abstract Umbilical cord blood (CBU) is a valuable source of hematopoietic stem cells (HSCs) due to lower incidence of graft-versus-host disease. However, limited HSC counts restrict use in adults, necessitating improved methods for ex vivo expansion and improved HSC function. Mitofusin 2 …
us (code pays fourni par la source)
0 citations
bioRxiv (Cold Spring Harbor Laboratory)
Label-free, single-cell quantification of granulocyte macrophage progenitors from brightfield imaging
Yardena Ovadia, Kam W. Leong, Christian Elabd, Larry L. Luchsinger et autres
us (code pays fourni par la source)
1 citation
Cytotherapy
Sexual dimorphism in the mouse bone marrow niche regulates hematopoietic engraftment via sex-specific Kdm5c/Cxcl12 signaling
Xiaojing Cui, Liming Hou, Bowen Yan, Jinpeng Liu et autres
The bone marrow (BM) niche is critical in regulating hematopoiesis, and sexual dimorphism and its underlying mechanism in the BM niche and its impact on hematopoiesis are not well understood. We show that male mice exhibited a higher abundance of leptin-receptor-expressing mesenchymal …
us (code pays fourni par la source)
12 citations
Journal of Clinical Investigation
Blood Pharming and Alternative Blood Products
Larry L. Luchsinger, Christopher D. Hillyer
us (code pays fourni par la source)
0 citations
Elsevier eBooks
List of Contributors
Rim Abdallah, Suchitra S. Acharya, Joel Addams, Ahmad H. Al-Huniti et autres
us, sa, in, nl, ca (code pays fourni par la source)
0 citations
Elsevier eBooks
3025 – MITOFUSIN 2 AGONISTS REGULATES MTOR SIGNALING TO SUPPORT HUMAN HSC EXPANSION IN VITRO
Alyssa Biondo, Gabriela de Toledo Passos Candelaria, Daniel K. Jin, Emily Pei-Ying Lin et autres
us (code pays fourni par la source)
0 citations
Experimental Hematology
Hemolysis-driven IFNα production impairs erythropoiesis by negatively regulating EPO signaling in sickle cell disease
Yongshuai Han, Chengjie Gao, Yunfeng Liu, Huan Zhang et autres
ABSTRACT: Disordered erythropoiesis is a feature of many hematologic diseases, including sickle cell disease (SCD). However, very little is known about erythropoiesis in SCD. Here, we show that although bone marrow (BM) erythroid progenitors and erythroblasts in Hbbth3/+ thalassemia mice were increased …
us (code pays fourni par la source)
20 citations
Blood
Insights into highly engraftable hematopoietic cells from 27-year cryopreserved umbilical cord blood
Hal E. Broxmeyer, Larry L. Luchsinger, Rona Singer Weinberg, Alexandra Jimenez et autres
Umbilical cord blood transplantation is a life-saving treatment for malignant and non-malignant hematologic disorders. It remains unclear how long cryopreserved units remain functional, and the length of cryopreservation is often used as a criterion to exclude older units. We demonstrate that long-term …
us (code pays fourni par la source)
17 citations
Cell Reports Medicine
Abstract 16 Insights into Highly Engraftable Hematopoietic Cells from 27-Year Cryopreserved Umbilical Cord Blood
Hal E. Broxmeyer, Larry L. Luchsinger, Rona Singer Weinberg, Alexandra Jimenez et autres
Abstract Introduction Cord blood banking has consistently outpaced the utilization of cord blood units (CBUs). Thus, the average duration of cryopreservation among banked CBUs will likely continue to increase. It remains unclear how long cryopreserved CBUs remain functional, and it is critical …
us (code pays fourni par la source)
0 citations
Stem Cells Translational Medicine
BNTIC News n’est pas le producteur de ces données. Les publications sont interrogées à la demande dans Crossref, OpenAIRE, DOAJ, Europe PMC, HAL, DataCite, AfricArXiv, ROR et la Banque mondiale, sans clé d’accès. OpenAlex reste optionnel. Aucun service payant n’est nécessaire et aucune donnée externe n’est enregistrée en base. Consulter les sources et leurs limites.