Hye Kyeong Park

A Prospective Cohort Study on the Usage, Safety, and Efficacy of Delamanid in Patients With Pulmonary Multidrug-Resistant Tuberculosis in South Korea

Jeongha Mok, Haesook Seo, Youngsoo Cho, Taehoon Lee et autres

Abstract Background Delamanid has demonstrated potential in the treatment of multidrug-resistant (MDR) or rifampicin-resistant tuberculosis (TB); however, real-world data on its effectiveness and safety remain limited. Methods This prospective cohort study enrolled patients with pulmonary MDR-TB who were treated with a delamanid-containing …

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Impact of Multidrug-Resistant Bacterial Colonization on Clinical Characteristics, Antibiotic Treatment, and Clinical Outcomes of Hospital-Acquired Pneumonia

Jae Kyeom Sim, Kyung Hoon Min, Kwang Ha Yoo, Kyeongman Jeon et autres

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Estimating the prevalence and clinical significance of chronic obstructive pulmonary disease-obstructive sleep apnea overlap in South Korea

Jieun Kang, Hye Kyeong Park, Hyeon‐Kyoung Koo, Hyung Koo Kang et autres

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Increased Apolipoprotein B/Apolipoprotein A-I Ratio Is Associated With Decline in Lung Function in Healthy Individuals: The Kangbuk Samsung Health Study

Jong Hoo Lee, Hye Kyeong Park, Min‐Jung Kwon, Soo‐Youn Ham et autres

Background: Lung dysfunction and high apolipoprotein B/apolipoprotein A-I (apoB/apoA-I) ratio are both recognized risk factors for cardiovascular disease.However, few studies have examined the association between the apoB/ApoA-I ratio and lung function.Therefore, we investigated whether this ratio is associated with decreased lung function …

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Risk adjustment model for tuberculosis compared to non-tuberculosis mycobacterium or latent tuberculosis infection: Center for Personalized Precision Medicine of Tuberculosis (cPMTb) cohort database

Woo Jung Seo, Hyeon‐Kyoung Koo, Ji Yeon Kang, Jieun Kang et autres

BACKGROUND: The Center for Personalized Precision Medicine of Tuberculosis (cPMTb) was constructed to develop personalized pharmacotherapeutic systems for tuberculosis (TB). This study aimed to introduce the cPMTb cohort and compare the distinct characteristics of patients with TB, non-tuberculosis mycobacterium (NTM) infection, or …

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Do patients attempt and succeed in quitting smoking during tuberculosis treatment? A prospective cohort study

Jiwon Lee, Chaeuk Chung, Sung Soo Jung, Hye Kyeong Park et autres

BACKGROUND: Despite a well-known relation between smoking tobacco and the tuberculosis epidemic, the factors associated with smoking cessation in tuberculosis patients are unclear. This study aims to examine the cascade of smoking cessation and the factors associated with persistent smoking among tuberculosis …

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Serum Krebs von den Lungen-6 (KL-6) level as a prognostic biomarker in patients with interstitial lung abnormalities (ILA)

Hye Kyeong Park, Young-Soon Yoon, Jae‐Uk Song, Hyung Koo Kang

Introduction: Interstitial lung abnormalities (ILA) are often observed as ancillary findings of chest CT indicating early pulmonary fibrosis. Data relating to the association of the disease progression with serum biomarkers, including white blood cell differential counts and Krebs von den Lungen-6 (KL-6) …

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Comparison of the end-of-life decisions of patients with hospital-acquired pneumonia after the enforcement of the life-sustaining treatment decision act in Korea

Ae-Rin Baek, Sang‐Bum Hong, Soohyun Bae, Hye Kyeong Park et autres

BACKGROUND: Although the Life-Sustaining Treatment (LST) Decision Act was enforced in 2018 in Korea, data on whether it is well established in actual clinical settings are limited. Hospital-acquired pneumonia (HAP) is a common nosocomial infection with high mortality. However, there are limited …

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Microbiologic pattern and clinical outcome of non-ICU-acquired pneumonia: Korean HAP registry analysis

Jin Ho Jang, Hye Ju Yeo, Taehwa Kim, Woo Hyun Cho et autres

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Serum Krebs von den Lungen-6 level as a prognostic biomarker in patients with interstitial lung abnormalities

Hyung Koo Kang, Jiyeon Kang, Woo Jung Seo, Jieun Kang et autres

Abstract Data associating progression of interstitial lung abnormalities (ILA) and serum biomarkers, including white blood cell differential counts and Krebs von den Lungen-6 (KL-6) are sparse. This study aimed to evaluate the relationship between disease progression and serum biomarkers in patients with …

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The impact of insulin resistance on the association between metabolic syndrome and lung function: the Kangbuk Samsung Health Study

Jong Hoo Lee, Hye Kyeong Park, Min‐Jung Kwon, Soo‐Youn Ham et autres

BACKGROUND/OBJECTIVE: Metabolic syndrome (MS) is related to lung dysfunction. However, its impact according to insulin resistance (IR) remains unknown. Therefore, we evaluated whether the relation of MS with lung dysfunction differs by IR. SUBJECT/METHODS: This cross-sectional study included 114,143 Korean adults (mean …

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Clinical phenotypes of chronic cough categorised by cluster analysis

Jiyeon Kang, Woo Jung Seo, Jieun Kang, So Hee Park et autres

BACKGROUND: Chronic cough is a heterogeneous disease with various aetiologies that are difficult to determine. Our study aimed to categorise the phenotypes of chronic cough. METHODS: Adult patients with chronic cough were assessed based on the characteristics and severity of their cough …

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