Keonayang Kgotlaetsile

Perspectives on adverse events reporting in hybrid implementation science (IS) clinical trials of approved medications in Sub-Saharan Africa

Keonayang Kgotlaetsile, Laura M. Bogart, Nabila Youssouf, Thato Moshomo et autres

Implementation science (IS) hybrid type 2 and 3 clinical trials and pure implementation research of approved medications test strategies to increase uptake of evidence-based interventions (EBIs) with well-established safety profiles. Guidance on adverse event (AE) monitoring and reporting for this type of …

Botswana, us, gb, Afrique du Sud (code pays fourni par la source)

Integrating hypertension care into the existing HIV services package in Botswana (InterCARE): a pair-matched, cluster-randomised, type 2 hybrid effectiveness–implementation trial

Mosepele Mosepele, Tendani Gaolathe, Kago Kebotsamang, Thato Moshomo et autres

BACKGROUND: People with HIV have poor access to care for other chronic conditions despite the increasing disease burden and associated mortality. We evaluated the impact of integrated HIV and hypertension care on blood pressure control, electronic prescribing of antihypertensive medicines, and HIV …

Botswana, gb, us, cn (code pays fourni par la source)

Social Connectedness and Sleep Disturbance Among Hypertensive Adults with and without HIV in Botswana

Lu Dong, L Bogart, David Klein, Keonayang Kgotlaetsile et autres

us, Botswana (code pays fourni par la source)

0269 Social Connectedness and Sleep Health Among People with HIV Compared to HIV-Negative Controls: Preliminary Findings from Botswana

Lu Dong, L Bogart, David Klein, Edwin Mogaetsho et autres

Abstract Introduction Sleep disturbance is common among people with HIV (PWH), even with viral suppression. Social connectedness may buffer stress-related effects on sleep, yet it is unclear whether objective (network size/diversity) and subjective (loneliness) isolation function differently for PWH and HIV-negative adults. …

us, Botswana (code pays fourni par la source)

Self-reported early-onset menopause among women living with HIV and hypertension in Botswana: a cross-sectional study

Onkabetse Julia Molefe‐Baikai, Kago Kebotsamang, Gorata Duduzile Manyeagae, Thato Moshomo et autres

OBJECTIVES: Early-onset menopause has been increasingly observed among women living with HIV (WLWH). However, limited data exist on its prevalence and determinants in sub-Saharan Africa. This study aimed to determine the prevalence and predictors of self-reported early-onset menopause among WLWH in Botswana. …

Botswana, us, gb (code pays fourni par la source)

Spatial distribution of central obesity in rural and peri urban communities of Botswana: a nested Botswana Combination Prevention Project (BCPP) cross-sectional study

Matlhogonolo Kelepile, Kago Kebotsamang, Moagedi Mawi, Kesaobaka Molebatsi et autres

BACKGROUND: Obesity is a growing public health concern, particularly in Sub-Saharan Africa, where undernutrition and obesity are in conjuction. In Botswana, the urban transition and environmental factors are likely influencing obesity risk. This study aimed to investigate the spatial distribution of central …

Botswana, us (code pays fourni par la source)

Integrated Hypertension-HIV Care in Botswana: Mixed-Methods Evaluation of Determinants of Success in an Implementation Trial

Amelia E. Van Pelt, Moagedi Mawi, Keonayang Kgotlaetsile, Mareko Ramotsababa et autres

Abstract Due to the success of HIV treatment, people living with HIV (PWH) have aged to develop chronic conditions. InterCARE is evaluating the integration of hypertension treatment into HIV care in Botswana. This involves adapting the Electronic Health Records [EHR], health care …

us, Botswana, gb (code pays fourni par la source)

Internalized HIV Stigma, Sleep Problems, and Depressive Symptoms in People with HIV in Botswana

Lu Dong, Laura M. Bogart, David J. Klein, Nthabiseng Phaladze et autres

This study investigates the impact of internalized HIV stigma on sleep problems and depression in people living with HIV (PLWH) in Botswana. It also explores whether sleep problems mediate the relationship between internalized HIV stigma and depressive symptoms, given that sleep disturbance …

us, Botswana (code pays fourni par la source)

Qualitative Evaluation of Treatment Partners for People With HIV in Botswana: Current Healthcare Provider Practices and Recommendations for Improvement

Laura M. Bogart, Nthabiseng Phaladze, Keonayang Kgotlaetsile, Kathy Goggin et autres

Botswana has an adult HIV prevalence of 20.8% and annual incidence of 0.2%. We aimed to evaluate current practices and advance recommendations for treatment partners (informal adherence supporters) for people with HIV in Botswana. In January-February 2020, we conducted seven focus groups …

us, Botswana (code pays fourni par la source)

Feasibility and Acceptability of Human Immunodeficiency Virus Self-Testing for Men of Middle-to-Upper Socioeconomic Status in Botswana: A Pilot Study at 4 Worksites in the Financial Sector

Keonayang Kgotlaetsile, Laura M. Bogart, Nthabiseng Phaladze, David J. Klein et autres

Background: Although Botswana has made great progress in expanding human immunodeficiency virus (HIV) testing, men are less likely to be tested for HIV and test at a later stage compared with women. For Botswana to increase HIV testing coverage among men, HIV …

Botswana, us (code pays fourni par la source)

Author Correction: Pilot Test of Mopati, a Multi-Level Adherence Intervention for People Living with HIV and Their Treatment Partners in Botswana

Laura M. Bogart, Nthabiseng Phaladze, Keonayang Kgotlaetsile, David J. Klein et autres

us, Botswana (code pays fourni par la source)

Pilot Test of Mopati, a Multi-Level Adherence Intervention for People Living with HIV and Their Treatment Partners in Botswana

Laura M. Bogart, Nthabiseng Phaladze, Keonayang Kgotlaetsile, David J. Klein et autres

BACKGROUND: Low-cost, scalable strategies are necessary to reach the UNAIDS 2030 target of ending HIV as a public health threat. Use of treatment partners, informal caregivers selected by people living with HIV to support antiretroviral therapy adherence, is one such strategy that …

us, Botswana (code pays fourni par la source)