Isabelle Holscher

Learning curve of blood pressure management during phaeochromocytoma surgery without preoperative alpha-blockade dose escalation

Isabelle Holscher, Mahsoem Ali, Koen M.A. Dreijerink, Markus W. Hollmann et autres

BACKGROUND: Adrenalectomy without preoperative dose escalation of α-blockade is gaining popularity for managing phaeochromocytoma, showing comparable outcomes but shorter hospital stays and less postoperative hypotension. However, recent data showed an initial significant increase in intraoperative hypotension after transitioning to this approach, suggesting …

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Evaluation of differences in presentation and postoperative outcomes after adrenalectomy for pheochromocytoma according to age

Sukhdeep Jatana, Kevin Verhoeff, Yanbo Wang, Zhicheng Wang et autres

Online ahead of print.

Incidence and risk factors of venous thromboembolism in an adrenocortical carcinoma patient cohort

Nienke Visser, Isabelle Holscher, C. Willemien Menke‐van der Houven van Oordt, Anton F. Engelsman et autres

Adrenocortical carcinoma (ACC) is a rare and aggressive endocrine malignancy. Venous thromboembolic events (VTE) have been reported in ACC patients. ACC is often associated with endogenous hypercortisolism, which is linked to increased VTE risk. The primary objective of this retrospective study in …

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Evaluation of the effect of tumour size on outcomes for patients undergoing adrenalectomy for phaeochromocytoma: international multicentre analysis

Steffane McLennan, Kevin Verhoeff, Alessandro Parente, A. Ribano et autres

BACKGROUND: Surgical resection is the standard treatment for phaeochromocytoma (PCC). Current guidelines recommend an open approach for large tumours due to the increased risk of complications. This study aimed to characterize surgical outcomes for large (≥ 6 cm) and small (< 6 …

ca, us, gb, cn, pl, it, au, kr, lt, gr, no, tr, nl, jp, mx, es, nz, th, sa, be, sg (code pays fourni par la source)

Feasibility of an Electronic Nose to Aid Biochemical Assessment of Adrenal Lesions

Charlotte L. Viëtor, Odin V Sosef, Sam P. J. van Dijk, Isabelle Holscher et autres

OBJECTIVES: Analysis of volatile organic compounds (VOCs) in exhaled breath has emerged as a promising noninvasive diagnostic tool for various diseases. The aim of this study was to evaluate the potential of an electronic nose to differentiate between functional adrenal lesions - …

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PERSPECTIVE: Challenging preoperative α-blockade in phaeochromocytoma surgery: beyond tradition, towards ‘safer surgery’

Isabelle Holscher, Koen M.A. Dreijerink, Markus W. Hollmann, Tijs J. van den Berg et autres

The rarity of phaeochromocytomas has left a gap in evidence supporting guideline recommendations for preoperative α-blockade dose-escalation. Despite recent studies questioning its efficacy, randomized-controlled trials (RCTs) are warranted before considering omitting preoperative α-blockade dose-escalation. Through an online survey, opinions on the ideal …

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Postoperative Outcomes in Normotensive and Hypertensive Pheochromocytomas: An International Study

Marta Araujo‐Castro, Aura D. Herrera‐Martínez, Yanbo Wang, Zhicheng Wang et autres

CONTEXT: Postoperative outcomes of patients with normotensive pheochromocytomas are poorly documented. OBJECTIVE: We aimed to evaluate the impact of preoperative hypertension on postoperative outcomes following adrenalectomy for pheochromocytoma. METHODS: An international retrospective study of patients undergoing adrenalectomy for pheochromocytoma in 46 centers …

es, cn, pl, it, au, gb, kr, lt, tr, nl, jp, mx, us, ch, nz, th, gr, sa, be, sg, ca (code pays fourni par la source)

Postoperative outcomes in normotensive and hypertensive pheochromocytomas: an international study

Marta Araujo-Castro, Aura Herrera, Yanbo Wang, Zhicheng Wang et autres

Art. no. dgaf154

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ASO Visual Abstract: Outcomes for Patients with Obesity Undergoing Adrenalectomy for Pheochromocytoma—An International Multicenter Analysis

Kevin Verhoeff, Alessandro Parente, Yanbo Wang, Nanya Wang et autres

ca, gb, cn, pl, it, au, kr, lt, gr, tr, nl, jp, mx, us, ch, es, nz, th, sa, be, sg (code pays fourni par la source)

Outcomes for Patients with Obesity Undergoing Adrenalectomy for Pheochromocytoma: An International Multicenter Analysis

Kevin Verhoeff, Alessandro Parente, Yanbo Wang, Nanya Wang et autres

ca, gb, cn, pl, it, au, kr, lt, gr, tr, nl, jp, mx, us, ch, es, nz, th, sa, be, sg (code pays fourni par la source)

Robotic and Laparoscopic Adrenalectomy for Pheochromocytoma: An International Multicenter Study

Alessandro Parente, Kevin Verhoeff, Yanbo Wang, Nanya Wang et autres

gb, ca, cn, pl, it, au, kr, lt, no, tr, nl, jp, mx, us, ch, es, nz, th, gr, sa, be, sg (code pays fourni par la source)

Omitting the Escalating Dosage of Alpha-adrenergic Blockade Before Pheochromocytoma Resection

Isabelle Holscher, Anton F. Engelsman, Koen M.A. Dreijerink, Markus W. Hollmann et autres

OBJECTIVE: This study describes the effects of introducing a protocol omitting preoperative α-blockade dose-escalation (de-escalation) in a prospective patient group. BACKGROUND: The decline of mortality and morbidity associated with pheochromocytoma resection is frequently attributed to the introduction of preoperative α-blockade. Current protocols …

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