Heterogeneous metabolic response of endothelial cells from different vascular beds to experimental hyperglycaemia and metformin
Corey A. McAleese, Ghadeer Joudah, Ian P. Salt, John R. Petrie et autres
Endothelial cells (ECs) are highly glycolytic, with mitochondria primarily serving a signalling function. Metabolic disruptions are early contributors to endothelial dysfunction, a primary feature of diabetic vascular complications, such as retinopathy, impaired wound healing and cerebral small vessel disease. The degree to …
gb, sa (code pays fourni par la source)
7 citations
The Journal of Physiology