Debbie Troland

Autologous macrophage therapy for liver cirrhosis: a phase 2 open-label randomized controlled trial

Paul Brennan, Mark T. Macmillan, Thomas Manship, Francesca Moroni et autres

Cirrhosis is a major cause of morbidity and mortality; however, there are no approved therapies except orthotopic liver transplantation. Preclinical studies showed that bone-marrow-derived macrophage injections reduce inflammation, resolve fibrosis and stimulate liver regeneration. In a multicenter, open-label, parallel-group, phase 2 randomized …

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LBP-007 Beneficial effects of autologous macrophage therapy on clinical outcomes in patients with compensated cirrhosis: extended follow-up data from a randomized controlled phase 2 trial

Paul Brennan, Iain Macpherson, Debbie Troland, Alastair M. Kilpatrick et autres

OP26 Effect of COVID-19 on presentations of decompensated liver disease in Scotland

Tom Manship, Paul Brennan, Iona Campbell, S. J. Campbell et autres

The COVID-19 pandemic has presented unique challenges. Beyond the direct COVID-related mortality in those with liver disease, we sought to determine the effect of lockdown on people with liver disease in Scotland. The effect of lockdown on those with alcohol-related disease is …

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Effect of COVID-19 on presentations of decompensated liver disease in Scotland

Thomas Manship, Paul Brennan, Iona Campbell, S. Campbell et autres

BACKGROUND AND AIMS: SARS-CoV-2 and consequent pandemic has presented unique challenges. Beyond the direct COVID-related mortality in those with liver disease, we sought to determine the effect of lockdown on people with liver disease in Scotland. The effect of lockdown on those …

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A prospective evaluation of the Bristol prognostic score: poor sensitivity and specificity in a non-Bristol cohort

Sarah Bowers, Alana Brown-Kerr, Debbie Troland, Iain Hay et autres

Coronavirus in Scotland: The effect of COVID-19 lockdown on admissions with chronic liver disease

Thomas Manship, Debbie Troland, M. Johnston, Paul Brennan et autres

Background: COVID-19 lockdown began in Scotland on 23rd March 2020 This was followed by a significant reduction in unselected medical admissions to Scottish hospitals with increased illness severity and in-patient mortality This study aimed to investigate the specific effect of lockdown on …

Endotherapy of Peptic Ulcer Bleeding

Debbie Troland, Adrian J. Stanley

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12 weeks of sofosbuvir, daclatasvir and ribavirin for GT3 patients with cirrhosis

Debbie Troland, Ray Fox, Joseph E. Morris, M Priest et autres

Loperamide

Debbie Troland, Gerry McKay, Miles Fisher

Diabetes is associated with significant gastrointestinal symptoms including constipation, diarrhoea and faecal incontinence. Advanced glycation end products, as a consequence of poor glycaemic control, lead to damage to cellular DNA and tissues in the myenteric nerve plexus causing autonomic neuropathy. This affects …

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