Eden Silva e Souza

Microbial catalysis for the production of hydroxy- and amino-fatty acids

Eden Silva e Souza

This study focused on the microbial synthesis of 3-hydroxybutyric acid (3HBA), which is industrially relevant but can also be converted into non-coded amino fatty acids. Synthetic operons combining the acetoacetyl-CoA thiolase gene (phaA) from C. necator, either the (R)- (phaB) or (S)-3-hydroxybutyryl-CoA …

Scaffold repositioning of spiro-acridine derivatives as fungi chitinase inhibitor by target fishing and in vitro studies

Jéssika de Oliveira Viana, Eden Silva e Souza, Nicolau Sbaraini, Marilene Henning Vainstein et autres

Abstract The concept of “one target, one drug, one disease” is not always true, as compounds with previously described therapeutic applications can be useful to treat other maladies. For example, acridine derivatives have several potential therapeutic applications. In this way, identifying new …

br, ie (code pays fourni par la source)

Identification of spiro-acridine derivatives as fungi chitinase inhibitor by target fishing and in vitro studies

Jéssika de Oliveira Viana, Eden Silva e Souza, Nicolau Sbaraini, Marilene Henning Vainstein et autres

ie, br (code pays fourni par la source)

Antimicrobial Peptide Analogs From Scorpions: Modifications and Structure-Activity

Bruno Amorim-Carmo, Adriana Marina e Silva Parente, Eden Silva e Souza, Arnóbio Antônio da Silva-Júnior et autres

The rapid development of multidrug-resistant pathogens against conventional antibiotics is a global public health problem. The irrational use of antibiotics has promoted therapeutic limitations against different infections, making research of new molecules that can be applied to treat infections necessary. Antimicrobial peptides …

br, ie (code pays fourni par la source)

Prospecção Tecnológica da Utilização dos Ácidos Graxos de Óleos Vegetais na Indústria de Cosméticos

Larissa Cardoso Souza, Eden Silva e Souza, Cátia Valéria dos Santos Passos Brito, Michely Correia Diniz

O aumento do consumo sustentável na cosmetologia tem desencadeado um maior uso de matérias-primas naturais para o desenvolvimento de formulações. Os óleos vegetais contêm ácidos graxos fundamentais para o organismo. O objetivo deste trabalho é executar uma prospecção tecnológica sobre o uso …

br, ie (code pays fourni par la source)

Intra-hemocoel injection of pseurotin A from Metarhizium anisopliae, induces dose-dependent reversible paralysis in the Greater Wax Moth (Galleria mellonella)

Nicolau Sbaraini, Chin‐Soon Phan, Eden Silva e Souza, Ana Paula A. Perin et autres

br, au (code pays fourni par la source)

A Plumieridine-Rich Fraction From Allamanda polyantha Inhibits Chitinolytic Activity and Exhibits Antifungal Properties Against Cryptococcus neoformans

Eden Silva e Souza, Vanessa de Abreu Barcellos, Nicolau Sbaraini, Júlia Catarina Vieira Reuwsaat et autres

Cryptococcosis is a fungal infection caused mainly by the pathogenic yeasts Cryptococcus neoformans and Cryptococcus gattii. The infection initiates with the inhalation of propagules that are then deposited in the lungs. If not properly treated, cryptococci cells can disseminate and reach the …

br (code pays fourni par la source)

Genetic diversity of 16S rRNA and mcrA genes from methanogenic archaeas

Keyla Vitória Marques Xavier, Eden Silva e Souza, Erick de Aquino Santos, Michely Correia Diniz

Methanogenic archaeas are found in aquatic and terrestrial environments and are fundamental in the conversion of organic matter into methane, a gas that has a potential use as renewable source of energy, which is also considered as one of the main agents …

br (code pays fourni par la source)

Análise do alvo predito da plumieridina em Cryptococcus neoformans

Eden Silva e Souza

Prediction of mutations on structure primase of the archaeon Sulfolobus solfataricus

Eden Silva e Souza, Michely Correia Diniz

All living organisms need a DNA replication mechanism and it has been conserved in the three domains of life throughout evolutionary process. Primase is the enzyme responsible for synthesizing de novo RNA primers in DNA replication. Archaeo-Eukaryotic Primase (AEP) is the superfamily …

br (code pays fourni par la source)