Kurtis F. Budden

Impact assessment of telehealth medical nutrition therapy for managing cardiovascular disease risk in rural and remote NSW: the Healthy Rural Hearts study

Kurtis F. Budden, Tracy L. Schumacher, Raquel A. Cameron, Priscilla Viana da Silva et autres

BACKGROUND: The impact of clinical trials extends beyond knowledge gained. However, broader impacts, including social, health and economic benefits to patients and communities are rarely assessed. In rural and remote regions where inclusion of local populations in clinical trials is limited, these …

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Innovative methodologies for elucidating bushfire smoke-induced pathophysiological mechanism

Keshav Raj Paudel, Karl J. Hegarty, Jesus Shrestha, Kurtis F. Budden et autres

Over the last century, the awareness of air pollution awareness and its harm to public health have resulted in the implementation of new protective measures to try and limit exposure. Bushfires generate waves of air pollution with orders of magnitudes higher than …

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Oral lactoferrin reduces systemic inflammation, enhances anti-viral responses and modulates immune cell profiles: a randomised controlled trial in healthy, older adults

Bronwyn S. Berthon, Evan J. Williams, Lily M. Williams, Kurtis F. Budden et autres

Abstract This randomised controlled trial examined the effect of a 4-week, high-dose (Lf-High, 600 mg/d) or low-dose (Lf-Low, 200 mg/d) oral lactoferrin (Lf) intervention v . placebo on immune cell responses to respiratory virus, immune cell subsets and systemic inflammation. In healthy …

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Multi-omics to study chronic respiratory diseases and viral infections.

Sobia Idrees, H Chen, Tayyaba Sadaf, Saima Firdous Rehman et autres

Despite recent advances, the underlying mechanisms of the development and progression of many chronic respiratory diseases remain to be elucidated. Factors such as heterogeneity and complexity of human diseases and difficulty interpreting large datasets hinder research into chronic respiratory diseases. Omics assesses …

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Evaluation of the Aged Care On-site Pharmacist (ACOP) program in Australian residential aged care homes: Key considerations and next steps

Janet Kathleen Sluggett, Daria S. Gutteridge, A. G. Calder, Georgina A. Hughes et autres

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Immune modulating effects of oral lactoferrin in healthy, older adults: a randomised controlled trial

Bronwyn S. Berthon, Evan J. Williams, Lily M. Williams, Kurtis F. Budden et autres

Immunoceuticals are natural products used to enhance immunity(1). Lactoferrin (Lf) is an immunoceutical supplement which has been shown to have immunomodulatory properties(2). The immuno-protective functions of Lf are of interest in older adults, as immune function declines with increasing age(3). This study …

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Editorial: Lung microbiome in health and disease

Kurtis F. Budden, Luigina R. Romani

In lung carcinogenesis, Zhai et al describes the interplay between bacteria and their metabolites in different early-stage lung cancer specimens that could be used as potential biomarkers to guide future therapeutic strategies (3). Different microbial richness was found in the different specimens, …

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Faecal microbial transfer and complex carbohydrates mediate protection against COPD

Kurtis F. Budden, Shakti Dhar Shukla, Kate L Bowerman, Annalicia Vaughan et autres

Objective Chronic obstructive pulmonary disease (COPD) is a major cause of global illness and death, most commonly caused by cigarette smoke. The mechanisms of pathogenesis remain poorly understood, limiting the development of effective therapies. The gastrointestinal microbiome has been implicated in chronic …

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Editorial: Microbiota and asthma

Brandon Bautista-Becerril, Kurtis F. Budden, Ramcés Falfán‐Valencia

EDITORIAL article Front. Allergy, 14 November 2023Sec. Asthma Volume 4 - 2023 | https://doi.org/10.3389/falgy.2023.1297425

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Fecal microbial transfer and complex carbohydrates mediate protection against COPD

Kurtis F. Budden, Shakti Dhar Shukla, Kate L Bowerman, Shaan L. Gellatly et autres

ABSTRACT Objective Chronic obstructive pulmonary disease (COPD) is a major cause of global illness and death, most commonly caused by cigarette smoke. The mechanisms of pathogenesis remain poorly understood, limiting the development of effective therapies. The gastrointestinal microbiome has been implicated in …

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Comparison of commercially available differentiation media on cell morphology, function, and anti-viral responses in conditionally reprogrammed human bronchial epithelial cells

Nikhil T Awatade, Andrew T. Reid, Kristy Nichol, Kurtis F. Budden et autres

Primary air liquid interface (ALI) cultures of bronchial epithelial cells are used extensively to model airway responses. A recent advance is the development of conditional reprogramming that enhances proliferative capability. Several different media and protocols are utilized, yet even subtle differences may …

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Comparison of Commercially Available Differentiation Media on Cell Morphology, Function, and Anti-Viral Responses in Conditionally Reprogrammed Human Bronchial Epithelial Cells

Nikhil T Awatade, Andrew T. Reid, Kristy Nichol, Kurtis F. Budden et autres

Abstract Introduction: Primary air liquid interface (ALI) cultures of bronchial epithelial cells are used extensively to model airway responses. A recent advance is the development of conditional reprogramming that enhances proliferative capability. Several different media and protocols are utilized, yeteven subtle differences …

au (code pays fourni par la source)