K.V. Gorbunova

Sinonasal symptoms and systemic type 2 inflammation markers in children with concomitant asthma and allergic rhinitis: the impact of polypoid-hyperplastic changes of the sinonasal mucosa

S.V. Krasilnikova, K.V. Gorbunova, D.Yu. Ovsyannikov, V. I. Popadyuk et autres

BACKGROUND: Bronchial asthma and allergic rhinitis often concomitant to form a single clinical and pathogenetic syndrome based on the activation of T2 inflammation. Important biomarkers of this type of inflammation are eosinophils and total immunoglobulin E. Prolonged course of allergic rhinitis in …

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Influence of age and sex on values of SNOT-22 sinonasal test domains in children and adolescents with bronchial asthma

S.V. Krasilnikova, Adam Koleśnik, K.V. Gorbunova, Т.И. Елисеева et autres

Influence of sex and age on manifestations of sinonasal symptoms in children and adolescents with comorbid course of allergic rhinitis (AR) and bronchial asthma (BA) remains unstudied. Objective. To study age-related and sex-specific influence on the domains of validated SNOT-22 (Syno-Nasal Outcome …

ru, us (code pays fourni par la source)

Inflammatory mediators in nasal secretion in patients with bronchial asthma and allergic rhinitis with or without polyposis and hypertrophic sinonasal mucosa

S.V. Krasilnikova, Ekaterina Ivanovna Krestova, Т.И. Елисеева, R.N. Khramova et autres

Aim: The pathogenetic mechanisms and predictors of the development of polyposis and hypertrophy of the sinonasal mucosa (SM) in patients with chronic allergic airway inflammation have not been clearly established. The concentration of inflammatory biomarkers in nasal secretions was determined in children …

ru (code pays fourni par la source)

Association of cough complaints with spirometry, nasal breathing in patients with asthma and allergic rhinitis

R.N. Khramova, S.V. Krasilnikova, Adam Koleśnik, K.V. Gorbunova et autres

Aim: Cough is an important symptom of the combined course of bronchial asthma (BA) and allergic rhinitis (AR) and/or allergic rhinosinusitis (ARS), but the contribution of the pathology of the upper and lower airway to the formation of cough in these patients …

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Peak nasal inspiratory flow in the assessment of nasal airway obstruction

S.V. Krasilnikova, Adam Koleśnik, K.V. Gorbunova, Т.И. Елисеева et autres

RELEVANCE: Nasal congestion is one of the most common complaints in otolaryngology practice and can significantly impact the quality of life for patients. Objective and subjective assessments provide different information, but objective assessment of nasal obstruction is crucial for accurate diagnosis and …

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Состояние околоносовых пазух у детей и подростков с пролонгированными синоназальными симптомами по данным компьютерной томографии

S.V. Krasilnikova, K.V. Gorbunova, Т.И. Елисеева, D.Yu. Ovsyannikov et autres

Chronic rhinosinusitis (CRS) with and without nasal polyps is a syndrome associated with the persistent inflammation and remodeling of the sinonasal mucosa (SM) leading to prolonged sinonasal symptoms (SNS). Its prevalence in children and adolescents has not yet been established. The diagnostic …

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IMPACT OF AGE AND GENDER ON SPIROMETRIC PARAMETERS IN ADOLESCENTS WITH BRONCHIAL ASTHMA

K.V. Gorbunova, R.N. Khramova, Т.И. Елисеева, D.Yu. Ovsyannikov et autres

Peculiarities of the course of bronchial asthma (BA) in adolescents from the standpoint of the influence of age and gender on it cannot be considered fully studied as yet. Materials and methods used: the data were obtained from 367 patients’ records of …

Effect of the intranasal interferon-alpha-2b medicine on the dynamics of clinical, functional and immunological parameters in patients with concomitant allergic rhinitis and bronchial asthma

S.V. Krasilnikova, K.V. Gorbunova, Т.И. Елисеева, M.T. Maigadzhieva et autres

Objective. A longitudinal cohort study was conducted to assess the effect of intranasal recombinant interferon α-2b-based medicine (Grippferon) on clinical, functional and immunological parameters in patients with concomitant bronchial asthma (BA) and allergic rhinitis (AR). Patients and methods. Twelve children aged between …

The relationship of synonasal symptoms with systemic and local markers of inflammation in children with bronchial asthma and allergic rhinitis

K.V. Gorbunova, S.V. Krasilnikova, Т.И. Елисеева, D.Yu. Ovsyannikov et autres

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