Control of ice thickness in cryo-EM via confinement
Liming Zheng, Jiling Song, Xiaole Zhao, 曹家枞 et autres
Achieving thin ice with optimal thickness is a prerequisite for successful cryo-EM analysis of embedded macromolecules. Despite decades of effort, precise control of ice thickness in cryo-EM remains a major challenge. Here, we reveal that the intrinsic instability of sub-100-nm liquid film, …
sg, cn, hk (code pays fourni par la source)