Eva Filipovská

Shared and distinct circadian and molecular effects of ADAR2 deficiency and the Gria2 R/R rescue allele

M. N. Lebedeva, Kamila Weissová, Marek Schwarz, Viktor Kuchtiak et autres

cz, ru (code pays fourni par la source)

STAT3 signaling and m6A RNA modification as modulators of circadian rhythms and neuroimmune signaling in the SCN

Eva Filipovská

The circadian system organizes physiological processes over a 24-hour period. In mammals, the central pacemaker of circadian rhythms is located in the suprachiasmatic nuclei (SCN) of the hypothalamus. At the cellular level, circadian rhythmicity is mediated by molecular clocks composed of transcription-translation …

Stat3 Silencing Affects Circadian Clock Gene Expression and Lipopolysaccharide Response in the Suprachiasmatic Nucleus, Cortex, and Glioblastoma Cell Cultures

Eva Filipovská, Kateřina Skálová, Veronika Spišská, Jorge E. Mendoza et autres

In mammals, the suprachiasmatic nucleus (SCN) serves as the central circadian pacemaker, regulating rhythms essential for physiological processes. STAT3, a transcription factor primarily involved in immune signaling, exhibits circadian rhythmicity in SCN astrocytes. This study examined the role of STAT3 in circadian …

cz, fr (code pays fourni par la source)

The role of N6‐methyladenosine RNA methylation in the crosstalk of circadian clock and neuroinflammation in rodent suprachiasmatic nuclei

Eva Filipovská, Zuzana Čočková, Barbora Černá, Aneta Kubištová et autres

Abstract N6‐methyladenosine (m 6 A) is the most abundant epitranscriptomic mark that regulates the fate of RNA molecules. Recent studies have revealed a bidirectional interaction between m 6 A modification and the circadian clock. However, the precise temporal dynamics of m 6 …

cz (code pays fourni par la source)

Author response for "The role of N6‐methyladenosine RNA methylation in the crosstalk of circadian clock and neuroinflammation in rodent suprachiasmatic nuclei"

Eva Filipovská, Zuzana Čočková, Barbora Černá, Aneta Kubištová et autres

The disruption of circadian rhythmicity of gene expression in the hippocampus and associated structures in Gria2 mice; a comparison with C57BL/6J and Adar2 mice strains

M. N. Lebedeva, Aneta Kubištová, Veronika Spišská, Eva Filipovská et autres

cz, jp (code pays fourni par la source)

The disturbance of circadian rhythmicity of clock gene expression in Gria2R/R mice; the comparison with C57BL/6J and Adar2-/- mice strains

Maria A. Lebedeva, Aneta Kubištová, Veronika Spišská, Eva Filipovská et autres

Abstract Adar2-/- mice are a widely used model to study the physiological consequences of reduced RNA editing. These mice are viable only when the Q/R editing site of the Gria2 subunit of the AMPA receptor is constitutively mutated to the codon for …

cz (code pays fourni par la source)

The Circadian Rhythms of STAT3 in the Rat Pineal Gland and Its Involvement in Arylalkylamine-N-Acetyltransferase Regulation

Simona Moravcová, Eva Filipovská, Veronika Spišská, Irena Svobodová et autres

In rodents, the melatonin production by the pineal gland is controlled through adrenergic signaling from the suprachiasmatic nuclei and regulation of the principal enzyme in its synthesis, arylalkylamine-N-acetyltransferase (AANAT). In the present study, we identified increased isoprenaline-induced aa-nat expression and nocturnal AANAT …

cz (code pays fourni par la source)

The effect of the cannabinoid receptor agonist and antagonist on the light-induced changes in the suprachiasmatic nucleus of rats

Eva Filipovská, Kateřina Červená, Simona Moravcová, Jiřı́ Novotný et autres

cz (code pays fourni par la source)

Vliv endokanabinoidního systému na světelnou synchronizaci cirkadiánního systému potkana

Eva Filipovská

The effect of endocannabinoid system on light entrainment of rat circadian system

Eva Filipovská

Circadian system of mammals is generated in suprachiasmatic nuclei of hypothalamus. This system is synchronized with light conditions through phase shifts that occur after light exposition during the subjective night. Recent studies have shown that activation of endocannabinoid receptors attenuates the light-induced …

Poruchy cirkadiánních rytmů u bipolárních depresí a jejich spojení s polymorfismem ve vápníkovém kanálu L-typu

Eva Filipovská