Lue Zhou

Mental health implications in the older adults of internet access in China

Chi Zhang, Lue Zhou, Xiaoyu Cheng

Social isolation is a significant factor contributing to mental health issues among the older adults, particularly in societies experiencing rapid population aging. Notably, digital technology offers an effective means to address this issue. However, little is known that how access to internet …

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Genetic and clinical investigation of insulin-degrading enzyme in Parkinson’s disease within the Chinese Han population

Huimin Zheng, Yu Guo, Lue Zhou, Yun Su et autres

Introduction Growing evidence suggests a mechanistic link between type 2 diabetes mellitus and Parkinson’s disease (PD), with insulin-degrading enzyme (IDE) implicated in both insulin and amyloid-β metabolism, as well as α-synuclein degradation. However, the role of IDE in PD pathogenesis remains insufficiently …

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Sleep patterns and DNA methylation age acceleration in middle-aged and older Chinese adults

Tingyue Diao, Kang Liu, Lue Zhou, Qiu-Hong Wang et autres

BACKGROUND: Sleep is a biological necessity and fundamental to health. However, the associations of sleep patterns (integrating sleep determinants) with DNA methylation age acceleration (DNAm AA) remain unknown. We aimed to investigate the associations of sleep patterns with DNAm AA. METHODS: This …

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Development and validation of AI delineation of the thoracic RTOG organs at risk with deep learning on multi-institutional datasets

Xianghua Ye, Dazhou Guo, Lujun Zhao, Congying Xie et autres

Introduction: Accurate contouring of thoracic organs at risk (OARs) is essential for minimizing complications in radiation treatment. Manual contouring of thoracic OARs is not only time-consuming but also prone to substantial user variation. To enhance the efficiency and consistency, we developed a …

Associations of Plasma Metabolites With Risks of Incident Stroke and Its Subtypes in Chinese Adults

Rundong Niu, Hao Wang, Rong Peng, Wei Wang et autres

Background Metabolomics studies have identified various metabolic markers associated with stroke risk, yet much uncertainty persists regarding heterogeneity in these associations between different stroke subtypes. We aimed to examine metabolic profiles associated with incident stroke and its subtypes in Chinese adults. Methods …

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Changes in sleep score and leisure-time physical activity, their combination, and all-cause mortality in middle-aged and older Chinese adults: The Dongfeng-Tongji cohort study

Tingyue Diao, Kang Liu, Lue Zhou, Junrui Lyu et autres

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Changes in Sleep Patterns, Genetic Susceptibility, and Incident Cardiovascular Disease in China

Tingyue Diao, Kang Liu, Junrui Lyu, Lue Zhou et autres

Importance: The associations of changes in sleep patterns with incident cardiovascular disease (CVD) are not fully elucidated, and whether these associations are modified by genetic susceptibility remains unknown. Objectives: To investigate the associations of 5-year changes in sleep patterns with incident CVD …

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Global, regional, and national burden of stroke attributable to extreme low temperatures, 1990–2019: A global analysis

Lue Zhou, Yujie Wei, Yahao Ge, Yapeng Li et autres

BACKGROUND: Extreme ambient temperatures have been linked to increased risks of stroke morbidity and mortality. However, global estimates of the burden of stroke due to extreme low temperatures are not well-defined. AIMS: This study aimed to determine the global burden of stroke …

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Bedtime, sleep duration, and sleep quality and all-cause mortality in middle-aged and older Chinese adults: The Dongfeng-Tongji cohort study

Tingyue Diao, Lue Zhou, Liangle Yang, Yu Lai Yuan et autres

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Residential greenness alleviated the adverse associations of long-term exposure to ambient PM1 with cardiac conduction abnormalities in rural adults

Bota Baheti, Gongbo Chen, Zhongao Ding, Ruiyu Wu et autres

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Bedtime, sleep pattern, and incident cardiovascular disease in middle-aged and older Chinese adults: The dongfeng-tongji cohort study

Tingyue Diao, Kang Liu, Qiu-Hong Wang, Junrui Lyu et autres

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Effect of prior anticoagulation therapy on stroke severity and in-hospital outcomes in patients with acute ischemic stroke and atrial fibrillation

Lue Zhou, Yapeng Li, Xin Yang, Hongqiu Gu et autres

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