Qiansi Chen

The ABA receptor NtPYL6 promotes flavonol biosynthesis to enhance tobacco resistance to UV-B

Zhong Wang, Li Xu, Haitao Huang, Y F LIU et autres

ABA and flavonol accumulation protect plants against UV-B radiation damage. However, the molecular mechanism by which UV-B enhances ABA signaling to induce flavonol biosynthesis remains largely unknown. Here, we found that ABA receptor ntpyl6 (PYRABACTIN RESISTANCE 1-LIKE6) mutants are more sensitive to …

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Chemoproteomic Identification of ALDOA as the Glycolytic Target of α-Cembratriene-4,6-diol in Lung Cancer Cells

Zhonghao Sun, Pingping Liu, Guoxu Ma, Xinyao Li et autres

Tobacco ( Nicotiana tabacum L.) is a globally important economic crop and a rich source of bioactive cembratriene-4,6-diol (CBT-diol). The unique macrocyclic scaffold of these compounds has prompted an extensive study of its bioactivity. Although CBT-diol has known antitumor activity, its specific …

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Molecular basis of trypsin's autolysis resistance acetylation for sustained enzymatic activity

Xiaozhan Qu, Tengfei Liu, Yalong Xu, Chen Wang et autres

Acetylation serves as an effective strategy to enhance trypsin's resistance to autolysis, yet the underlying molecular mechanism remains unclear. Integrating molecular dynamics (MD) simulations and biochemical assays, we show that acetylation induces global stabilization (RMSD decreased by 0.03 nm) coupled with structural …

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Repurposing the food flavoring agent 3-mercapto-2-butanone as a potent polyphenol oxidase inhibitor for fresh-cut product preservation

Chang Ge, Qian Gao, Xueao Zheng, Chen Wang et autres

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Deep learning-guided engineering of pectinase for enhanced catalytic performance in tobacco processing

Xueao Zheng, T. Liu, Xiaozhan Qu, Zeping Sun et autres

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Gold Nanocluster-Based Sensor Array with PCA-Assisted Pattern Recognition for Discriminating Multiple Antibiotics in Different Complex Biological Samples

Liu P, Jiaheng Shi, Ying Wang, Peijian Cao et autres

Principal component analysis (PCA)-assisted pattern recognition combined with sensor arrays shows great potential for direct antibiotic identification in complex biological samples, addressing critical needs in health monitoring and food safety. However, conventional approaches often require cumbersome surface modifications of multiple functional nanomaterials …

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Green-synthesized silver nanoparticles as an effective tool for promoting tobacco (Nicotiana tabacum L.) growth and development

Xingyue Huang, Qingxia Zheng, Qiansi Chen, Xiaojing Cui et autres

Tobacco ( Nicotiana tabacum L.) is a model plant and significant cash crop in agriculture. However, it is exposed to a variety of biotic and abiotic stressors, which not only affect its growth and development but also reduce its yield and quality. …

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Phosphate-mobilizing bacterial community structure and mobilization mechanisms in tobacco rhizosphere

Yalong Xu, Liqiang Zhu, Jing Li, Fan Zhang et autres

strains displayed exceptional genetic flexibility, harboring more P mobilization genes than other phyla strains. Greenhouse experiments demonstrated that PSB strains significantly enhanced tobacco seedling growth, including shoot and root biomass, stem diameter and leaf area, increased both plant P content and rhizosphere …

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Development of an Efficient Bifunctional Endoxylanase/Feruloyl Esterase Chimera for Coproduction of Ferulic Acid, p -Coumaric Acid, and Xylooligosaccharides

Yizhou Liu, Yingyu Shu, Shuangcheng Liang, Qiansi Chen et autres

Bifunctional endoxylanases/feruloyl esterases that can efficiently produce hydroxycinnamic acids and xylooligosaccharides from agricultural residues are highly desirable but underexplored. Here, we report the development of a bifunctional chimera, XynB-SnT-FaeB, which shares low sequence identity (<23%) with its homologues and contains a novel …

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Exposure to organochlorine pesticides and mortality risk among individuals with diabetes: A prospective cohort analysis and network pharmacology study

Lingjun Yan, Haohuan Li, Xuejing Zhong, Bingqin Xie et autres

Emerging evidence suggests a potential link between organochlorine pesticides (OCPs) and diabetes, yet their impact on mortality risk among diabetic individuals is poorly understood. This longitudinal study assessed 1846 diabetic participants from the National Health and Nutrition Examination Surveys (2003-2016) with mortality …

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Bacteria dynamics and its correlation with chemical composition changes in tobacco leaves during flue curing

Yunfei Sha, Demin Liang, Jie Yu, Yan-Jiu Bi et autres

Microorganisms play a vital role in tobacco growth and processing, yet their correlation with chemical composition during flue curing is understudied. This study examines the dynamic changes in chemical components and bacterial communities during flue curing of lower, middle, and upper leaves. …

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Proteomics and metabolomics analyses of tobacco protoplasts under Cd stress

Chun Wang, Huina Zhou, Niu Zhai, Qiansi Chen et autres

Cadmium (Cd), a highly toxic non-essential heavy metal, disrupts cellular processes even at low concentrations. The current studies of Cd stress rely on whole-plant models with prolonged treatments, obscuring early response signals. Tobacco, a typical model plant, lacks protoplast-level investigations under Cd …

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