Carlos Álvarez-Moya

Genetic Damage to Human Lymphocytes Induced by Contaminated Water in Populations Surrounding Lake Chapala and the Santiago River, Jalisco, México

Mónica Reynoso Silva, Carlos Álvarez-Moya, Fernando Manuel Guzmán-Rubio, Daniela Guadalupe Velázquez-Cruz et autres

Polluted water in the Chapala–Santiago basin (CSB) contains several genotoxic substances that present risks to human health, particularly among residents of communities surrounding Lake Chapala and the Santiago River, where a high prevalence of cancer has been documented. For this reason, it …

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Genetic damage in human blood cells exposed to germicidal lamps and cytoprotection of ascorbic acid

Mónica Reynoso Silva, Carlos Álvarez-Moya, J. Jesús Vargas Radillo, Lucía Barrientos-Ramírez et autres

Introduction. Germicidal lamps have a wavelength range of 200-280 nm and can affect the integrity of the DNA of people who handle this equipment. Human lymphocytes are excellent biomonitors of genetic damage and widely used with the comet assay.Objective. Evaluation of genotoxicity …

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Chemical Composition, Antioxidant Properties, and Antibacterial Activity of Essential Oils of Satureja macrostema (Moc. and Sessé ex Benth.) Briq

Lucía Barrientos-Ramírez, José Antonio Silva Guzmán, Edison Osorio, Carlos Álvarez-Moya et autres

Satureja macrostema is a plant that is located in various regions of Mexico and is used in a traditional way against illness. Essential oils (EOs) were obtained from leaves Satureja macrostema and the chemical composition was evaluated by gas chromatography–mass spectrometry (GC-MS). …

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Assessment of Genetic Damage Induced via Glyphosate and Three Commercial Formulations with Adjuvants in Human Blood Cells

Carlos Álvarez-Moya, Mónica Reynoso Silva

There is considerable controversy regarding the genotoxicity of glyphosate (N-(phosphonomethyl) glycine). It has been suggested that the genotoxicity of this herbicide is increased by the adjuvants added to commercial formulations based on glyphosate. The effect of various concentrations of glyphosate and three …

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Concentration-associated genotoxicity of the herbicide marvel in Oreochromis niloticus erythrocytes and in human and mouse Balb/c lymphocytesalb/c

Mónica Reynoso Silva, Alma Rosa Villalobos Arámbula, Mario Alberto Ruíz Ramírez, Carlos Álvarez-Moya

The genotoxic activity of various concentrations of the marvel herbicide (0.76 μg/1 ml, 7.68 μg/1 ml, 76.8 μg/1 ml, 768 μg/1 ml) was evaluated in lymphocytes of humans and in Balb/c strain mice, as well as in erythrocytes of tilapia (Oreochromis niloticus). …

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Evaluation of Genetic Damage and Antigenotoxic Effect of Ascorbic Acid in Erythrocytes of Orochromis niloticus and Ambystoma mexicanum Using Migration Groups as a Parameter

Carlos Álvarez-Moya, Mónica Reynoso Silva, Lucía Barrientos-Ramírez, J. Jesús Vargas Radillo

The comet assay system is an efficient method used to assess DNA damage and repair; however, it currently provides the average result and, unfortunately, the heterogeneity of DNA damage loses relevance. To take advantage of this heterogeneity, migration groups (MGs) of cell …

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Antigenotoxic Effect of Ascorbic Acid and Resveratrol in Erythrocytes of Ambystoma mexicanum, Oreochromis niloticus and Human Lymphocytes Exposed to Glyphosate

Carlos Álvarez-Moya, Alexis Gerardo Sámano-León, Mónica Reynoso Silva, Rafael Ramírez-Velasco et autres

Glyphosate is a controversial herbicide. Its genotoxicity and presence in various ecosystems have been reported. The use of ascorbic acid and resveratrol could protect different organisms from glyphosate-induced genetic damage. In the present study, specific genetic damage induced by glyphosate was evaluated …

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Migration Groups: A Poorly Explored Point of View for Genetic Damage Assessment Using Comet Assay in Human Lymphocytes

Mónica Reynoso Silva, Carlos Álvarez-Moya, Rafael Ramírez-Velasco, Alexis Gerardo Sámano-León et autres

A new point of view for genetic damage assessment using the comet assay is proposed based on the number of migration groups, the number of comets in each group, and the groups with the highest number of comets. Human lymphocytes were exposed …

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ANTIMICROBIAL ACTIVITY PRESENT IN Ganoderma curtisii AQUEOUS EXTRACTS

Alfonso Enrique Islas Rodríguez, Dolores Marina Barragán Reynaga, Carlos Álvarez-Moya, Mónica Reynoso Silva et autres

Macroscopic mushrooms have proven to be excellent sources of protein.In addition to this, their medicinal properties have been noted, including their natural antitumor, antiviral, antimicrobial, and antioxidant action, as well as their role in immune system modulation.Although polysaccharides and triterpenoids have been …

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Presence of arsenic and potentially toxic metals (Cd, Cr, Pb) in water and soil of the NE shore of Chapala Lake, Mexico, and its genotoxic effect in the edible chayote fruit (Sechium edule (Jacq.) Sw.)

M.M. Maldonado-Villegas, Blanca Catalina Ramírez-Hernández, Martha Isabel Torres-Morán, Carlos Álvarez-Moya et autres

Antioxidant Capacity and Antigenotoxic Effect of Hibiscus sabdariffa L. Extracts Obtained with Ultrasound-Assisted Extraction Process

Gregorio Iván Peredo Pozos, Mario Alberto Ruíz-López, Juan Francisco Zamora Nátera, Carlos Álvarez-Moya et autres

Hibiscus sabdariffa (Roselle) is in high demand worldwide due to its beneficial health properties owing to the polyphenols content, mainly in the flower calyx. The objective of this study was to find the best conditions (time and liquid: solid ratio) to extract …

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Genotoxic Activity of Saccharin, Acesulfame-K, Stevia and Aspartame-Acesulfame-K in Commercial Form

Mónica Reynoso Silva, Carlos Álvarez-Moya, Alexis Gerardo Samano Leon, Rafael Ramirez Velasco et autres

Genotoxic activity of various concentrations of saccharin, acesulfame-K, aspartame-acesulfame-K and stevia in their commercial form was assessed. Human lymphocytes were exposed to different concentrations of saccharin, acesulfame-K, aspartame-acesulfame-K and stevia for 2 h and then subjected to alkaline comet assay system. Saccharin …