Yun Kee Jo

Inhalable Mucoadhesive Redox‐Triggered Nanotherapeutics for p53‐Mediated Lung Cancer Therapy and Metastasis Suppression

Y M Shim, Sung Min Han, Yun Kee Jo

Lung cancer remains a leading cause of cancer-related mortality worldwide, with metastatic disease accounting for ∼90% of deaths. While p53 gene therapy offers promise for restoring tumor suppressor function, its clinical translation has been hindered by inefficient delivery systems and pulmonary administration …

kr, Soudan (code pays fourni par la source)

Development strategies for engineered live biotherapeutic products for metabolic diseases

Saebom Yun, Kyu-Sung Choi, Heonhae Min, Yun Kee Jo et autres

Metabolic diseases, such as obesity and diabetes, have risen due to lifestyle changes. Traditional treatments, including dietary modifications and pharmacological interventions, are limited by low compliance and adverse effects, highlighting the need for alternative therapeutic approaches that offer improved patient compliance and …

ru, Soudan, kr (code pays fourni par la source)

Marine-inspired proteinaceous coacervates as an injectable extracellular matrix mimicry for enhanced stem cell delivery

Sung Min Han, Myeong Jae Baek, Yun Kee Jo

Injectable stem cell therapy offers advantages, including minimally invasive administration and expedited recovery. However, clinical translation remains limited due to substantial loss of injected cells—up to 90% within hours post-injection—from mechanical stress, hostile microenvironments, and insufficient extracellular matrix (ECM) interactions. Here, we …

kr (code pays fourni par la source)

Self-disinfecting adhesive chitosan nanospray therapeutics for on-demand antibiotic prophylaxis against healthcare-associated infections

Jungil Choi, Mou Seung Kim, Yun Kee Jo

kr (code pays fourni par la source)

Bandgap-engineered proteinic near-infrared nanodots for localized precision cancer theranostics

Mou Seung Kim, Il-woo Nam, Hyung Joon Chi, Yun Kee Jo

Silver sulfide (Ag2S) quantum dots hold tremendous potential as promising near-infrared (NIR) theranostic agents for cancer treatment owing to their exceptional photophysical properties and deep tissue penetration capabilities. However, their complex synthesis process under harsh reaction conditions and poor retention at the …

kr, Soudan (code pays fourni par la source)

Identification and validation of robust housekeeping genes for quantitative genotypic analyses in translational intestinal organoid studies

Dong Chang Kim, Sung‐Ho Kim, Min Beom Kim, Won‐Jae Lee et autres

kr, Soudan (code pays fourni par la source)

Near-infrared-activatable angiogenic proteinaceous nanomicelles for sequential augmentation of bone repair in periodontal defects

Mou Seung Kim, Dong Chang Kim, Yun Kee Jo

kr (code pays fourni par la source)

Angiogenic sticky porous microgels as injectable stem cell carriers for site-directed treatment of osteoporosis

Yun Kee Jo, Kyoung‐Ik Min, Dong‐Pyo Kim, Hyung Joon Chi

kr (code pays fourni par la source)

Redox-activatable inhalable mucoadhesive proteinic nanotherapeutics for targeted treatment of lung cancer

Yeonsu Jeong, Yun Kee Jo, Hyung Joon Chi

kr (code pays fourni par la source)

In Situ Photo-Crosslinkable Protein Bioadhesive for Bone Graft Fixation

Jieun Yun, Inhyuk Nam, Hyowon Lee, Yun Kee Jo et autres

Bone grafting is a fundamental dental surgery procedure widely used for implant placement and periodontal disease management treatments. Despite its broad applications, vertical bone augmentation presents unique challenges, including the risk of graft displacement due to gravitational and masticatory forces. Traditional physical …

kr (code pays fourni par la source)

Self-controllable proteinic antibacterial coating with bacteria-triggered antibiotic release for prevention of periprosthetic infection

Hyun Sun Choi, Jinyoung Yun, Yeonsu Jeong, Yun Kee Jo et autres

kr (code pays fourni par la source)

Multi-bioinspired Sprayable Nanotherapeutics for Tumor-Specific Focal Cancer Therapy

Yu Ri Jeon, Yun Kee Jo

kr, Soudan (code pays fourni par la source)