Jesús Vargas‐Barrón

An Exploratory Study on Two Exogenous Estrogenic Metabolites (EDMs): Their Effects In Vitro and on Oophorectomized Female Rats

Alejandro Silva‐Palacios, Gabriela Navarrete-Anastasio, Elizabeth Lira‐Silva, Leonardo del Valle‐Mondragón et autres

Background: For a long time, it was thought that estrogen degradation metabolites (EDMs) had no role in the female body, but this view has changed. Despite the progress, there are still unknowns about EDMs and the heart. We found that EDMs affect …

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Estrogen Degradation Metabolites: Some Effects on Heart Mitochondria

Cristina Uribe‐Alvarez, Elizabeth Lira‐Silva, Lilia Morales‐García, Natalia Chiquete‐Félix et autres

Mitochondria play crucial roles in various cellular functions, including ATP production, apoptosis, and calcium homeostasis. Signaling pathways and hormones such as estrogens regulate the mitochondrial network through genetic, epigenetic, and metabolic processes. Estrogens increase the efficiency of mitochondrial oxidative phosphorylation by preventing …

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Bioprosthesis in aortic valve replacement. Long-term inflammatory response and functionality.

Huitzilihuitl Saucedo‐Orozco, Jesús Vargas‐Barrón, Ricardo Márquez-Velasco, Karla Susana Martinez-Zavala et autres

Abstract Background. The evaluation of long-term inflammatory response and function in postoperative patients with aortic valve replacement (AVR) deserves special analysis because it is important to try to prevent reoperation and improve durability and functionality of the prostheses. Methods In this study …

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Possible implication of estrogenic compounds on heart disease in menopausal women

Elizabeth Lira‐Silva, Leonardo del Valle‐Mondragón, Israel Pérez-Torres, Rosalinda Posadas‐Sánchez et autres

Epidemiological studies imply there is a higher risk of cardiovascular disease in menopausal women. Some explanations suggest a lack of estrogens as the cause, but estrogens do not disappear completely and are just transformed into different products called estrogenic degradation metabolites (EDMs). …

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Bioprosthesis in aortic valve replacement: long-term inflammatory response and functionality

Huitzilihuitl Saucedo‐Orozco, Jesús Vargas‐Barrón, Ricardo Márquez-Velazco, Julio Iván Farjat-Pasos et autres

BACKGROUND: The evaluation of long-term inflammatory response and function in postoperative patients with aortic valve replacement (AVR) deserves special analysis because it is important to try to prevent reoperation and improve durability and functionality of the prostheses. It is our objective METHODS: …

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Echocardiographic findings in patent ductus arteriosus-associated infective endarteritis

Huitzilihuitl Saucedo‐Orozco, Jesús Vargas‐Barrón, Clara A Vázquez-Antona, Francisco Castillo-Castellón

BACKGROUND: Infectious endarteritis associated with patent ductus arteriosus (PDA-IE) is an uncommon complication in the era of antibiotics. However, it implies a clinical challenge in patients with a fever of undetermined origin; Two-dimensional transthoracic echocardiography (TTE) performs a fundamental role in diagnosis …

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Modification of Serum Natriuretic Peptide Profile and Echocardiographic Parameters After Surgical Left Atrial Appendage Exclusion/Resection During Mitral Valve Surgery

Jesús Vargas‐Barrón, Huitzilihuitl Saucedo‐Orozco, Alicia Sánchez-Mendoza, Ricardo Márquez-Velasco et autres

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Bone Morphogenetic Protein-2 and Osteopontin Gene Expression in Epicardial Adipose Tissue from Patients with Coronary Artery Disease Is Associated with the Presence of Calcified Atherosclerotic Plaques

María Luna‐Luna, Sergio Críales-Vera, Diana Jhoseline Medina-Leyte, Mariana Díaz‐Zamudio et autres

Purpose: It has been proposed that the cardiovascular effects of obesity are related to epicardial adipose tissue (EAT), which seems to play an active role on the development and calcification of atherosclerotic plaques, but the mechanisms are still unknown. Therefore, the aim …

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Echocardiographic Findings in Canine Model of Chagas Disease Immunized with DNA Trypanosoma cruzi Genes

Olivia Rodríguez-Morales, Francisco‐Javier Roldán, Jesús Vargas‐Barrón, Enrique Parra-Benítez et autres

-sialidase protein and an amastigote-specific glycoprotein were tested as vaccines in canine model. The aim for this study was determining the prophylactic effect of these genes in experimentally infected dogs by echocardiography evaluation to compare with our findings obtained by other techniques …

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Resection of the Atrial Appendages and its Impact in the Natriuretic Homeostasis: Development and Validation of an Animal Model in an Academic Medical Center

Ricardo Márquez-Velasco, Maité Vallejo, Jorge Manuel Catrip-Torres, María del Carmen Lespron-Robles et autres

BACKGROUND: The left atrial appendage (LAAp) resection is an effective treatment approach to reduce the risk of thromboembolism in patients with atrial fibrillation. OBJECTIVE: To study was to study the impact of removing atrial appendages in the production of natriuretic peptides (NPs) …

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Cardiovascular findings by echocardiography in canine model of Chagas disease immunized with DNA Trypanosoma cruzi genes.

Olivia Rodríguez-Morales, Francisco‐Javier Roldán, Jesús Vargas‐Barrón, Enrique Parra-Benítez et autres

Abstract Background: Chagas disease (ChD) is nowadays considered as an emerging disease in the USA and Europe. pBCSP and pBCSSP4 plasmids, containing Trypanosoma cruzi genes encoding a trans -sialidase protein and an amastigote-specific glycoprotein, respectively, were tested as vaccines in canine model. …

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Evaluation of the global longitudinal strain and segmental strain of the right ventricle with two-dimensional speckle-tracking echocardiography with elevation of the legs

Zaira Yadira García-López, Jesús Vargas‐Barrón

Introduction: Speckle-tracking echocardiography has shown its usefulness in the evaluation of the right ventricle (RV) in healthy subjects and in pulmonary hypertension. It is unknown whether this technique could be sensitive to assess healthy RV with increases in preload. Methods: equipment. The …

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