Ka Lam Wong

Machine Learning–Based risk stratification in patients with direct anti‑xa Inhibitors–Related bleeding treated with four‑factor prothrombinex complex concentrate (4F-PCC)

Chun Fung SIN, Yuen Ting Sin, Chung Yin Ha, Sze Fai Yip et autres

Abstract Introduction: Patients taking direct oral anticoagulants (DOACs), including direct anti-Xa inhibitors, have risk of major bleeding with substantial morbidity and mortality. Although Andexanet alfa is FDA-approved for reversal, its high cost and limited availability restrict its use in many centers. Off-label …

hk, cn (code pays fourni par la source)

Transfemoral Transcatheter Aortic Valve Implantation (TF‐TAVI) for Patients With Left Ventricular Assist Device (LVAD) and Aortic Regurgitation

Daniel Tai‐Leung Chan, Ho-On Alston Conrad Chiu, Ka Lam Wong, Ka‐Chun Un et autres

Aortic regurgitation (AR) develops in up to 25%-30% of patients with left ventricular assist device (LVAD). Treatment remains challenging since surgery confers significant peri-operative risk and the lack of valvular calcification renders transfemoral transcatheter aortic valve implantation (TF-TAVI) with non-dedicated devices technically …

cn, hk, us (code pays fourni par la source)

An Atypical Case of Burkitt Lymphoma With MYC Gain and Cryptic IGH :: MYC Rearrangement Detected by Rapid Nanopore Sequencing

Ka Ngai Lau, Tsz Fung Wong, Lawrence Lap Chi Tsui, Ka Lam Wong et autres

The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.

cn, hk (code pays fourni par la source)

Clinical Features and Disease Phenotypes as Study Entry Criteria for Scleroderma Encompass Patients with Significant Biological Heterogeneity

Ka Lam Wong, Maximilien Lora, Qihuang Zhang, Melanie C. Baniña et autres

Objectives Clinical trials in systemic sclerosis (SSc) define strict eligibility criteria to overcome the known heterogeneity of the disease. We evaluated baseline circulating cytokines in participants of the Phase I/II Randomized Controlled Clinical Trial of Umbilical Cord-Derived Mesenchymal Stromal Cells in Systemic …

ca, fr, us (code pays fourni par la source)

Pericardial Decompression Syndrome in a Patient With Severe Valvular Disease Resulting in Refractory and Fatal Pulmonary Edema

Aron Soleiman, Ka Lam Wong

us (code pays fourni par la source)

Trends in contemporary advanced heart failure management: an in-depth review over 30 years of heart transplant service in Hong Kong

Yue Yan Katherine Fan, Ka Lam Wong, Ka Lai Cally Ho, Daniel Tai‐Leung Chan et autres

Background: The year 2022 marks the 30th anniversary of heart transplant service in Hong Kong (HK). In this study, we describe prevailing trends and outcomes of advanced heart failure (AHF), including heart transplantations (HTx), in HK over the past 30 years. Methods: …

cn, hk (code pays fourni par la source)

The hemodynamic characteristics of severe chronic lung disease referred for lung transplantation

Wood H. I. Ling, Chi Fong Wong, See Wan Yan, Yue Yan Katherine Fan et autres

Abstract Severe pulmonary hypertension (PH) is not common even in patients with severe chronic lung disease (CLD) but data on hemodynamic characteristics among patients with severe CLD is scarce. All adult patients who had right heart catheterization for lung transplant assessment for …

cn (code pays fourni par la source)

EMERGING ROLES OF LEFT VENTRICULAR ASSIST DEVICE THERAPY AS BRIDGE TO TRANSPLANT IN AN ASIAN CITY WITH SCARCE HEART TRANSPLANT DONOR

Ka Lam Wong, Cally Ho, Timmy WK Au, S.-P. Lam et autres

Introduction: Limited organ availability remained a major hurdle for heart transplant in Hong Kong (HK). In 2019, there were only 8 heart transplantations in a 7.5 million populations. This had negative impact on the time and mortality on transplant waiting list. Left …

cn (code pays fourni par la source)

P101 Cardiac rehabilitation program for end-stage heart failure patients with left ventricular assist devices in Hong Kong

K Fan, Ka Lam Wong, Ning Fu, K. Y. Cheng et autres

Abstract Background Implantation of modern durable left ventricular assist device (LVAD) in advanced heart failure (HF) patients is associated with increased survival and improved quality of life. Exercise-based cardiac rehabilitation (EBCR) has been demonstrated to exercise capacity in HF patients but data …

cn (code pays fourni par la source)

TIMI risk score for secondary prevention of recurrent cardiovascular events in a real-world cohort of post-non-ST-elevation myocardial infarction patients

Duo Huang, Yang Yang Cheng, Yiu Tung Anthony Wong, See Yue Arthur Yung et autres

BACKGROUND: Patients who survive non-ST-elevation myocardial infarction (NSTEMI) are at heightened risk of recurrent cardiovascular events. Data on long-term secondary atherothrombotic risk stratification are limited. OBJECTIVES: To stratify post-NSTEMI patients for risk of recurrent cardiovascular events to maximise benefit from aggressive secondary …

hk, cn (code pays fourni par la source)

Voltage-Gated K+ Channels Promote BT-474 Breast Cancer Cell Migration

Louis W.C. Chow, Kuo‐Sheng Cheng, Ka Lam Wong, Yuk‐Man Leung

Objective: A variety of ion channels have been implicated in breast cancer proliferation and metastasis. Voltage-gated K+ (Kv) channels not only cause repolarization in excitable cells, but are also involved in multiple cellular functions in nonexcitable cells. In this study we investigated …

mo, cn, tw (code pays fourni par la source)

Validation study of the Brief Medication Adherence Scale (BMAS) in patients with schizophrenia and related disorders in Hong Kong

E. Chui, Ka Lam Wong, K.Y. Chan, Michael M.C. Wong

cn (code pays fourni par la source)