Laura Rienzi

Evolving concepts in the world of vitrification

Miguel Gallardo, Ana Cobo, Laura Rienzi

PURPOSE OF REVIEW: Cryopreservation by vitrification has become a cornerstone of contemporary assisted reproductive technologies, enabling widespread use of embryo and oocyte banking and fundamentally reshaping IVF workflows. Although recent clinical practice has adopted shortened protocols for both preparation for vitrification and …

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Artificial intelligence in human-assisted reproduction: a paradigm shift still in search of clinical impact

Danilo Cimadomo, Giovanni Coticchio, Laura Rienzi

PURPOSE: Artificial intelligence in human-assisted reproduction has attracted intense interest and inflated expectations, with proposed applications ranging from ovarian stimulation to gamete and embryo selection and outcome prediction. Despite the initial enthusiasm, its real-world clinical value remains uncertain. This review critically reassesses …

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Misleading messages from the web: professional medical counseling and public datasets vs. online health information in in vitro fertilization

Alberto Vaiarelli, Danilo Cimadomo, Christine Wyns, Diane De Neubourg et autres

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An advanced SWOT analysis of elective vitrification: today’s standard IVF procedure

Christophe Blockeel, Roberto de Azevedo Antunes, Baris Ata, Gorka Barrenetxea et autres

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Oocyte vitrification reduces blastocyst yield but preserves reproductive competence in advanced maternal age patients undergoing oocyte accumulation with PGT-A

Stefano Canosa, Danilo Cimadomo, Roberta Maggiulli, Alberto Revelli et autres

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Changing the narrative for poor-prognosis patients in IVF: unlocking success through a multicycle approach

Alberto Vaiarelli, Carlo Alviggi, Juan Antonio Garcia Velasco, Marcos Horton et autres

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Random-Start Approach in Breast Cancer Patients: Are All Menstrual Cycle Phases the Same?

Giuseppe Gabriele Iorio, Marika Ylenia Rovetto, Luigi Carbone, Raffaella Di Girolamo et autres

OBJECTIVES: The aim of this study was to investigate the ovarian response in different phases of the menstrual cycle in breast cancer women candidates for fertility preservation. DESIGN: A retrospective study was carried out, including women with breast cancer undergoing oocyte cryopreservation …

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Rates and risk factors of oocyte immaturity: toward personalized selection for rescue in vitro maturation

Marilena Taggi, Roberta Maggiulli, Federica Innocenti, Valentina Casciani et autres

PURPOSE: To identify treatment-related factors influencing low oocyte maturation rates in standard ovarian stimulation (OS) cycles and patients' candidates for clinical studies on rescue-IVM. METHODS: Retrospective study including retrievals with ≥ 1 cumulus-oocyte-complex (COC; years: 2008-2022). The weighted-mean immaturityrate (19%) was defined …

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Rethinking embryology dogma: an expert opinion paper

Laura Rienzi, Catherine Racowsky

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The emerging role of the oocyte cortical domain in maturation, fertilization, and development

Giovanni Coticchio, Valentina Casciani, Laura Rienzi, Danilo Cimadomo et autres

The cell cortex, a cytoskeletal network with regulatory signalling pathways, is localized beneath the cell membrane: it is especially prominent in mammalian oocytes. As in other cells, the cortex ensures appropriate shape and robustness of oocytes. It is also involved in other …

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Rattling sabers over day-3 vs. blastocyst stage transfer: let us listen to the experts

Laura Rienzi, Dominique de Ziegler

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Rethinking embryology dogma

Catherine Racowsky, Jacques Cohen, David K. Gardner, Denny Sakkas et autres

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