Isabelle Brock

Management of childbearing with hypermobile Ehlers-Danlos syndrome and hypermobility spectrum disorders: A scoping review and expert co-creation of evidence-based clinical guidelines

Sally Pezaro, Isabelle Brock, Maggie Buckley, Sarahann Callaway et autres

OBJECTIVE: To co-create expert guidelines for the management of pregnancy, birth, and postpartum recovery in the context of hypermobile Ehlers-Danlos syndrome (hEDS) and hypermobility spectrum disorders (HSD). DESIGN: Scoping Review and Expert Co-creation. SETTING: United Kingdom, United States of America, Canada, France, …

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Contributors

Patrick Agnew, Molly S. Allison, Dan Atkins, Ralph W. Aye et autres

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Twitching

Isabelle Brock, C. Hamonet

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P168: Nutritional markers of histamine intolerance in Ehlers-Danlos syndromes

Jessica M Pizano, Alissa Zingman, Isabelle Brock, Anne L. Maitland et autres

Background: Sotos syndrome is a well-recognized condition that is estimated to occur in 1:14,000 live births.It is characterized by three cardinal features: distinct facies, overgrowth of height and head circumference, and learning disabilities.Cardinal features occur simultaneously in at least 90% of affected …

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Mast cell activation syndrome, Mannose binding lectin, Ehlers-Danlos syndrome, and Neuropsychiatric symptoms. (P17-1.004)

Ilene Ruhoy, Isabelle Brock, Anne L. Maitland

We sought to identify the prevalence of neuropsychiatric symptoms in patients with mannose binding lectin (MBL) deficiency, mast cell activation syndrome (MCAS), and hypermobile Ehlers-Danlos Syndrome (hEDS).

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Adult-onset mast cell activation syndrome following scombroid poisoning: a case report and review of the literature

Isabelle Brock, Nicole Eng, Anne L. Maitland

BACKGROUND: Mast cells are closely associated with epithelium, serving as sentinels responsible for the recognition of tissue injury and coordination of the initial inflammatory response. Upon detection of the injured cell content, mast cells then tailor the release of preformed and newly …

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Mast cell activation disease and immunoglobulin deficiency in patients with hypermobile Ehlers‐Danlos syndrome/hypermobility spectrum disorder

Isabelle Brock, Walter Prendergast, Anne L. Maitland

Mast cell activation disease (MCAD) includes single organ disease such as asthma, urticaria, and gastroenteritis, as well as multiorgan system involvement such as mast cell activation syndrome and anaphylaxis. Reports link MCAD with hypermobile Ehlers-Danlos syndrome (hEDS), hypermobility spectrum disorder (HSD), and …

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Adult-Onset Mast Cell Activation Syndrome Following Scombroid Poisoning a case report and review of the literature

Isabelle Brock, Nicole Eng, Anne L. Maitland

Abstract Mast Cell Activation syndrome (MCAS) is a clinical condition, defined by the combination of 1) typical symptoms, 2) laboratory abnormalities and 3) response to treatment. Patients present with episodic symptoms of aberrant mast cell activation, such as abdominal cramping, asthma, hypotensive …

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Frequency and co-occurrence of comorbidities in the Ehlers-Danlos syndromes

Isabelle Brock, Pradeep Chopra, Anne L. Maitland, Clair A. Francomano

Mast Cells and COVID-19: a case report implicating a role of mast cell activation in the prevention and treatment of Covid-19

Isabelle Brock, Anne L. Maitland

Coronavirus disease (COVID-19) is a heterogeneous syndrome following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of the upper respiratory tract. ln adults, the clinical condition can range from asymptomatic cases to severe acute respiratory syndrome and multi-organ dysfunction. Those at risk …

Mast Cells and COVID-19: a case report implicating a role of mast cell activation in the prevention and treatment of Covid-19

Isabelle Brock, Anne L. Maitland

Abstract Coronavirus disease (COVID-19) is a heterogeneous syndrome following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of the upper respiratory tract. ln adults, the clinical condition can range from asymptomatic cases to severe acute respiratory syndrome and multi-organ dysfunction. Those at …

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Mast Cells and COVID-19: a case report implicating a role of mast cell activation in the prevention and treatment of Covid-19

Isabelle Brock, Anne L. Maitland

Abstract Coronavirus disease (COVID-19) is a heterogeneous syndrome following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of the upper respiratory tract. ln adults, the clinical condition can range from asymptomatic cases to severe acute respiratory syndrome and multi-organ dysfunction. Those at …

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