Hiroki Konishi

271. A STUDY ON PREDICTORS FOR PROGRESSION-FREE SURVIVAL IN THE FIRST-LINE TREATMENT OF RECURRENT/UNRESECTABLE ESOPHAGEAL CANCER

Junichirô Itani, Takeshi Ishikawa, Toshifumi Doi, Daiki Sone et autres

Abstract Background In Japan, combination chemotherapy with 5-FU + CDDP (FP) and immune checkpoint inhibitors (ICIs) and dual ICI combination therapy have been approved for use in first-line treatment of recurrent/unresectable esophageal cancer since November 2021, and have become widely used in …

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Author Correction: Left atrial single-cell transcriptomics reveals amphiregulin as a surrogate marker for atrial fibrillation

Yuya Suzuki, Takuo Emoto, Shunsuke Sato, Takeshi Yoshida et autres

In the version of the article initially published, in the “Myeloid cells signal FBs via the EGF and platelet-derived growth factor (PDGF) pathways” section, the sentence “GO enrichment analysis revealed enrichment of ‘response to fibroblast growth factor’ and ‘myeloid leukocyte differentiation’ (biological …

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Left atrial single-cell transcriptomics reveals amphiregulin as a surrogate marker for atrial fibrillation

Yuya Suzuki, Takuo Emoto, Shunsuke Sato, Takeshi Yoshida et autres

Atrial fibrillation (AF) is strongly associated with strokes, heart failure, and increased mortality. This study aims to identify the monocyte–macrophage heterogeneity and interactions of these cells with non-immune cells, and to identify functional biomarkers in patients with AF. Therefore, we assess the …

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Potential microemboli formation risk and its management during the heated saline–enhanced radiofrequency needle-tip catheter ablation

Helge Immo Lehmann, Hiroki Konishi, Songyun Wang, Stephan W. Hohmann et autres

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Real‐world safety and effectiveness of tenofovir alafenamide for 144 weeks in Japanese patients with chronic hepatitis B

Shuhei Hige, Kouji Aoki, Daisuke Nakamoto, John F. Flaherty et autres

Tenofovir alafenamide (TAF), a prodrug of tenofovir, delivers high levels of active drug to hepatocytes and is given in a lower dose than tenofovir disoproxil fumarate (TDF). TAF reduces viral replication in patients with chronic hepatitis B (CHB) similar to TDF and …

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Minimally invasive coil embolization for significant left-to-right shunts due to giant coronary-to-pulmonary artery fistulas: a case report

Sato Namura, Hiroki Konishi, Ryo Nishio, Hiroshi Yamamoto

Background: Coronary-to-pulmonary artery fistula (CPF) is a rare disease, and its optimal treatment strategy remains controversial. Herein, we report a rare case of minimally invasive coil embolization of giant CPFs. Case summary: A 78-year-old man with a history of persistent atrial fibrillation …

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Acute myocarditis secondary to Campylobacter jejuni enteritis: A case report

Wako Suehiro, Ryo Nishio, Jun‐ichi Noiri, Ryo Takeshige et autres

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Early Impact of Proton Beam Therapy on Electrophysiological Characteristics in a Porcine Model

Kimitake Imamura, A. Deisher, Jannis Dickow, Maryam E. Rettmann et autres

Background: Particle therapy is a noninvasive, catheter-free modality for cardiac ablation. We previously demonstrated the efficacy for creating ablation lesions in the porcine heart. Despite several earlier studies, the exact mechanism of early biophysical effects of proton and photon beam delivery on …

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PO-02-182 OCCURRENCE OF PERICARDIAL AND INTRA-PERICARDIAL SPACE EFFUSIONS WITH PROTON BEAM ABLATION

Tatsuhiko Hirao, Kimitake Imamura, Atsushi Suzuki, Stephan W. Hohmann et autres

Assessment of cardiac gating in external beam ablation therapy of ventricular tachycardia

Maryam E. Rettmann, A. Deisher, Tatsuhiko Hirao, Naoto Otsuka et autres

Cardiac motion remains a challenge in the treatment of ventricular tachycardia with external beam ablation therapy. Current techniques involve expansion of the treatment area which can lead to unwanted collateral damage. Surrounding healthy tissue could be spared by gating the delivery of …

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The importance of pre‐ablation atrial septal evaluation for a patient with surgical patch closure history

Jun‐ichi Noiri, Hiroki Konishi, Hiroki Matsuzoe

Limited studies report on the status of surgical closure patches for atrial septal defect (ASD) in the remote period. In our case, transthoracic echocardiography revealed a fistula of ASD patch before pulmonary vein isolation for atrial fibrillation. Preoperative Imaging examinations aid in …

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Abstract 11620: Time Course of Pericardial Effusion After Catheter-Free Ventricular Ablation With Proton Beam in Swine Normal Heart

Tatsuhiko Hirao, Kimitake Imamura, Atsushi Suzuki, Maryam E. Rettmann et autres

Background: Cardiac proton beam ablation therapy has emerged as a promising tool for catheter-free arrhythmia ablation. The time course of the lesion change was demonstrated in MRI 8 weeks following the ablation; however, the pericardial effusion after the ablation has not been …

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