Nadeen N. Faza

Pooled Analysis of Valve‐in‐Valve and Valve‐in‐Ring Transcatheter Mitral Valve Replacement Using the SAPIEN Valve

Chloé Kharsa, Sahar Samimi, Ankit Agrawal, Safi Ullah Khan et autres

Background Transcatheter mitral valve replacement (TMVR) using the Sapien (Edwards Lifesciences, Irvine, CA) transcatheter heart valve has become the preferred treatment for high‐risk patients with failed mitral bioprosthetic valves or prior surgical mitral valve repairs. Differences in anatomy and procedural complexity between …

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Intraprocedural cardiac computed tomography-fluoroscopy image fusion guided structural heart intervention: a proof of concept experience during transcatheter aortic valve implantation

Joe Aoun, Kristian Kragholm, Chloe Kharsa, Rody G. Bou Chaaya et autres

Intraoperative image guidance using cardiac CT with fluoroscopy image fusion has been shown to facilitate structural heart interventions. However, there has been limited experience on CT image fusion with fluoroscopy using aortic root calcifications from intraoperative 3D cone-beam CT imaging. This study …

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Women in the Leadership of Interventional Structural Heart Disease Trials

Sahar Samimi, Chloe Kharsa, Saliha Erdem, Nadeen N. Faza et autres

BACKGROUND: Leadership structures in interventional structural heart disease (SHD) trials help shape trial design and conduct, yet women's representation in these roles remains poorly characterized. OBJECTIVES: The objectives of the study were to assess women's representation in trial oversight committees, leadership roles …

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Infective Endocarditis of Transcatheter Aortic Valve Replacement and Transcatheter Edge-to-Edge Repair Devices

Joe Aoun, Chloe Kharsa, Parth V. Desai, Karl Abou Zeid et autres

F-fluorodeoxyglucose positron emission tomography/computed tomography, show promise in enhancing diagnostic accuracy, standardized guidelines for management are lacking, especially regarding the appropriateness of antimicrobial suppression therapy. Future research should focus on refining diagnostic criteria, optimizing therapeutic strategies, and improving patient outcomes in these …

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Redo Transcatheter Aortic Valve Replacement for Degenerated Valve With High-Risk Coronary Anatomy

Chloe Kharsa, Gal Sella, Mangesh Kritya, Karl Abou Zeid et autres

OBJECTIVES: Here we describe a step-by-step, imaging-guided technical approach to redo transcatheter aortic valve replacement (TAVR) in a degenerated ACURATE Neo2 valve (Boston Scientific) with high-risk right coronary artery (RCA) anatomy and highlight strategies to prevent coronary obstruction during valve-in-valve implantation. KEY …

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Tricuspid Transcatheter Edge-to-Edge Repair in Orthotopic Heart Transplantation Recipients

Chloe Kharsa, Isadora Sande Mathias, Mangesh Kritya, Gal Sella et autres

Tricuspid regurgitation in orthotopic heart transplantation recipients is a common complication that has been associated with poor outcomes. Surgical intervention carries a high risk in this population given prior sternotomy, immunosuppression, and comorbidities. We report a case series of 4 orthotopic heart …

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Clinical Profile and Outcomes of Patients Deemed Ineligible for Transcatheter Tricuspid Valve Intervention

Chloe Kharsa, Gal Sella, Mangesh Kritya, Taha Hatab et autres

BACKGROUND: Transcatheter tricuspid valve intervention (TTVI) has expanded therapeutic options for tricuspid regurgitation (TR); however, a substantial proportion of patients remain ineligible because of anatomical and clinical constraints. We sought to characterize patients screened out from TTVI and evaluate their clinical outcomes. …

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2026 ACC/AHA/HRS advanced training statement on clinical cardiac electrophysiology (Revision of the 2015 ACC/AHA/HRS advanced training statement on clinical cardiac electrophysiology)

José A. Joglar, Julia H. Indik, Nadeen N. Faza, Sana M. Al-Khatib et autres

2026 ACC/AHA/HRS Advanced Training Statement on Clinical Cardiac Electrophysiology (Revision of the 2015 ACC/AHA/HRS Advanced Training Statement on Clinical Cardiac Electrophysiology): A Report of the ACC Competency Management Committee

José A. Joglar, Julia H. Indik, Nadeen N. Faza, Sana M. Al‐Khatib et autres

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2026 ACC/AHA/HRS Advanced Training Statement on Clinical Cardiac Electrophysiology (Revision of the 2015 ACC/AHA/HRS Advanced Training Statement on Clinical Cardiac Electrophysiology)

José A. Joglar, Julia H. Indik, Nadeen N. Faza, Sana M. Al-Khatib et autres

Transcatheter Paravalvular Leak Closure Using Valve Frame Access

Chloe Kharsa, Mangesh Kritya, Karl Abou Zeid, Charishma Nallapati et autres

OBJECTIVE: To describe a step-by-step approach to transcatheter paravalvular leak (PVL) closure after transcatheter aortic valve replacement (TAVR) using frame-based access through a self-expanding valve. KEY STEPS: An 85-year-old man with a 34-mm Evolut FX+ TAVR valve developed worsening heart failure. Multimodality …

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Transcatheter Tricuspid Valve Replacement in a Heart Transplant Recipient

Chloé Kharsa, Isadora Sande Mathias, Hassaan B Arshad, Catherine Teng et autres

BACKGROUND: Transcatheter tricuspid valve replacement (TTVR) is an emerging therapy for patients with severe tricuspid regurgitation (TR) who are often at prohibitive surgical risk. Orthotopic heart transplant recipients represent a particularly high-risk subgroup, frequently excluded from surgical intervention and underrepresented in clinical …

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