Yan Huo

Association between parity and adverse maternal and neonatal outcomes: a population-based cross-sectional study

Sisi Li, Jian Li, Liyan Du, Wang Xl et autres

Objective This study aimed to comprehensively assess the association between parity and adverse maternal and neonatal outcomes among Chinese women, particularly across different age and educational strata, in the context of recent changes in China’s birth policy. Methods This population-based cross-sectional study …

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Application of Loading Dose Warfarin in Postpartum Women with Pulmonary Embolism – a Prospective, Randomized, Double-Blind Trial

Weifeng Huang, Huiqin Sun, Lü Zhou, Yan Chen et autres

Purpose: Warfarin is usually used in a fixed loading dose regimen, which may increase the risk of bleeding or prolong the time to reach standard dose. The aim of the study is to compare the efficacy and safety of loading dose versus …

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Retinal features as predictive indicators for high myopia: insights from explainable multi-machine learning models

Haohan Zou, Jing Liu, Shenda Shi, Saiguang Ling et autres

Objectives To investigate the role of retinal characteristics for high myopia (HM) prediction based on multi-machine learning (ML) and to provide an interpretable framework for the results. Methods A total of 2981 patients (2981 eyes) were included, comprising 1191 HM eyes and …

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Epidemiology and Risk Factors of Sepsis and Sepsis-Induced Myocardial Dysfunction in the Intensive Care Units of Tertiary Hospitals

Guijun Zhu, Yan Huo, Yu-Chun Yin, Bo Li et autres

Sepsis and sepsis-induced myocardial depression (SIMD) are critical conditions associated with high mortality in intensive care units (ICUs). This study aimed to characterize the clinical profiles of sepsis and SIMD in tertiary ICUs, identify prognostic determinants, and enhance understanding of outcome-related risk …

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Discovery of Antioxidant Peptide Against Keap1 From Silkworm Protein Based on In Silico Study and In Vitro Antioxidant Activity Detection

Shuoliang Ye, Mengyue Qi, Jianhua Wang, Qiuyi Zhang et autres

ABSTRACT Nrf2‐Keap1 is an important defense system against oxidative stress damage and enhances the body's antioxidant capacity. Targeting the Keap1‐Nrf2 signaling pathway and activating Nrf2 has become an effective strategy for treating oxidative stress and related diseases. In this study, virtual digestion, …

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Corrigendum to “the inappropriateness of internal consistency testing and factor analysis for formative indicators: comment on Felicia et al, 2024” [Journal of Clinical Epidemiology 181 (2025) 111748]

Xin Meng, Daqiu Wang, Yan Huo, Aiping Wang

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Predicting the complex variation characteristics of equipment heat dissipation in office buildings via CNN-LSTM-ATT, multiple regression, and similar day models

Ruonan Li, Yuhao Hu, Zhichao Xu, Xinyao Shao et autres

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Effect Modification by Socioeconomic Status on the Associations between Early Placental Protein Damage and Exposure to Ambient Air PM 2.5 Chemical Components

Junnan Yang, Xuesong Li, Mengyu Chu, Mengyuan Wang et autres

BACKGROUND: ) exposure is associated with systemic protein damage in pregnant women. However, its effect on protein damage in human placentas is unclear. OBJECTIVES: and chemical component exposures with advanced oxidation protein products (AOPP) in placental villi tissues before 13 weeks of …

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Enhanced pre- and postnatal developmental toxicity (ePPND) study in non-human primates: Necessity, strategic approaches, and critical considerations

Jing Lu, Yawen Wang, J. Chih H. Shu, Zhiqi Lei et autres

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The inappropriateness of internal consistency testing and factor analysis for formative indicators: comment on Felicia et al, 2024

Daqiu Wang, Yan Huo, Aiping Wang

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Decreased renal cortical perfusion post-EGDT is associated with MAKE-30 in sepsis

Qiqi Li, Rong Li, Can Wang, Qian Zhang et autres

This study explores alterations in renal cortical perfusion post-Early Goal-Directed Therapy (EGDT) in sepsis patients, to investigate its association with major adverse kidney events within 30 days (MAKE-30) and identify hemodynamic factors associated with renal cortical perfusion. Sepsis patients admitted to the …

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A Nomogram Model Containing Genetic Polymorphisms to Predict Risk of Pulmonary Embolism in Pregnant Women

Huiqin Sun, Lu Zhou, Yihan Lu, Yingchuan Li et autres

Introduction: Pulmonary embolism (PE), the most serious presentation of venous thromboembolism (VTE), is associated with a high rate of mortality and expense. Clinical studies on pregnant women with PE are scarce. The aim of this study was to analyze the clinical impact …

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