Alex Lawoko

Natural IgM antibodies against human endogenous retroviruses HERV-H demonstrated by means of synthetic peptides

Rüdiger Pipkorn, Alex Lawoko, Jonas Blomberg

de, se (code pays fourni par la source)

V3-mediated neutralization of primary isolates. Serology with synthetic V3 peptides demonstrates deficiencies in anti-V3 response

Rüdiger Pipkorn, Alex Lawoko, Bo G. Johansson, BRITH CHRISTENSON et autres

'V3-mediated neutralization of primary isolates. Serology with synthetic V3 peptides demonstrates deficiencies in anti-V3 response' published in 'Peptides Frontiers of Peptide Science'

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Structural Prerequisites for Intersubtype B and D Antigenicity of the Third Variable Envelope Region (V3) of Human Immunodeficiency Virus Type 1

Alex Lawoko, Bo G. Johansson, Johan Ljunggren, Andreas Fries et autres

To elucidate the structural requirements for intersubtype antigenicity of human immunodeficiency virus type 1 (HIV-1) third variable envelope region (V3), synthetic peptides were used in enzyme immunoassays (EIAs) with serum samples from persons with proven or probable subtype B and D infections. …

se, de (code pays fourni par la source)

Increased immunoglobulin G, but not M, binding to endogenous retroviral antigens in HIV-1 infected persons

Alex Lawoko, Bo G. Johansson, Dash Rabinayaran, Rüdiger Pipkorn et autres

The modes of interaction between products of human endogenous retroviral (HERV) sequences and the immune system are largely unknown. In HIV infected persons, an exogenous retrovirus adds further complexity to the situation. Therefore, 14 synthetic peptides with sequences derived from conserved regions …

se, de (code pays fourni par la source)

Comparative studies on neutralisation of primary HIV-1 isolates by human sera and rabbit anti-V3 peptide sera

Alex Lawoko, Bo G. Johansson, Sandra Hjalmarsson, Bértil Christensson et autres

IgG binding to V3 peptides and serum neutralising responses were studied in four HIV-1 infected individuals with progressive disease over a period of 31-70 months. The 18-20 mer peptides comprised residues 299-317 (numbering of HIV1 MN) in the N-terminal half of the …

se, de (code pays fourni par la source)

Continuity and Discontinuity in the Anti-V3 IgG Response of Human Immunodeficiency Virus Type 1-Infected Persons in a Cross-Sectional and Longitudinal Study Using Synthetic Peptides

Alex Lawoko, Bo G. Johansson, Rupesh Dash, L. Falck et autres

The principal neutralization domain (PND) of the V3 region of human immunodeficiency virus type 1 (HIV-1) gp120 is central to HIV pathogenesis. The IgG antibody response to PND was followed in 15 HIV-1-infected persons from southern Sweden over 2-5 years using 32 …

se (code pays fourni par la source)

A survey of synthetic HIV-1 peptides with natural and chimeric sequences for differential reactivity with Zimbabwean, Tanzanian and Swedish HIV-1-positive sera

Jonas Blomberg, Alex Lawoko, Rüdiger Pipkorn, Sylvester Rodgers Moyo et autres

OBJECTIVE: To determine whether the known sequence differences between African and non-African HIV-1 strains are reflected in the serological response. DESIGN AND METHODS: We investigated the antibody reactivity of 34 Swedish, 30 Tanzanian and 42 Zimbabwean HIV-1-positive sera to 67 synthetic peptides …

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Structural requirements for geographically selective serological reactivity in the envelope glycoprotein of HIV-1

Ruediger Pipkorn, Jonas Blomberg, Alex Lawoko, Suzie Tetang Ndiang Moyo et autres

Seroepidemiology of Human Retroviruses in Ogun State of Nigeria

Olusegun Olusanya, Alex Lawoko, Jonas Blomberg

We analyzed sera collected during 1987 and 1988 from 385 healthy business employees of both sexes, of Ogun state in Nigeria, for antibodies to the 3 human retroviruses HIV-1, HIV-2 and HTLV-I. No serum was HIV-1 positive, 1 was HIV-2 positive and …

se, Nigéria (code pays fourni par la source)