Telotristat ethyl reverses myxomatous changes in mice mitral valves
Xinmei Wang, Danielle Kuban-Johnston, Pablo Lapuerta, Carla M. R. Lacerda
Rationale Myxomatous mitral valve degeneration is a common pathological manifestation of mitral valve regurgitation, with or without valvular prolapse. In addition to similarities between naturally occurring and serotonergic valve degeneration, an increasing body of evidence has recently suggested that serotonin signaling is …
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2 citations
Frontiers in Cardiovascular Medicine