Thérèse Masson

Efficacy of immunotherapy in gastrointestinal (GI) tumors with mismatch repair deficient (MMRd) unusual phenotype: an AGEO real-world study

Emily Alouani, Julien Taı̈eb, David Tougeron, Guillaume Roces et autres

BACKGROUND: Tumors with mismatch repair deficiency (MMRd) classically display concomitant loss of MLH1/PMS2 or MSH2/MSH6 on immunohistochemistry (IHC) with microsatellite instability-high (MSI-High) status on molecular testing. Nevertheless, a different phenotype can occur in up to 15% of MMRd tumors (unusual phenotype). Data …

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Real-world efficacy of immune checkpoint inhibitors in microsatellite unstable/mismatch repair-deficient biliary tract cancer: An AGEO study

Iona Campo-Le-Brun, Emma Grapinet, Valerie Aurillac, Antoine Hollebecque et autres

fr (code pays fourni par la source)

A multicenter study evaluating efficacy of immune checkpoint inhibitors in advanced non-colorectal digestive cancers with microsatellite instability

Mathilde Moreau, Emily Alouani, Clémence Flecchia, Antoine Falcoz et autres

BACKGROUND: One randomized phase III trial comparing chemotherapy (CT) with immune checkpoint inhibitors (ICI) has demonstrated significant efficacy of ICI in deficient DNA mismatch repair system/microsatellite instability-high (dMMR/MSI-H) metastatic colorectal cancer. However, few studies have compared ICI with CT in other advanced …

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My Kaddish

Thérèse Masson

“Elegant yet shattering… Rendered in plainspoken yet devastating prose, Masson’s historical narrative is intercut with startling present-day moments… This is haunting.” — Publishers Weekly “This heart-wrenching recollection views the traumatic events and close calls that punctuate the author’s memories… A brief, rare, …

Lettre d’Haïti

Thérèse Masson

Montréal by night

Thérèse Masson