Riccardo Tamburrini

Supraceliac Aortobifemoral Bypass for Live Donor Renal Transplant

Jack Bontekoe, Paul DiMusto, Riccardo Tamburrini, David Aufhäuser et autres

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Simultaneous Pancreas and Kidney Transplant Recipients From Pediatric Donors Have Comparable Outcomes to Those From Adult Donors, Regardless of the Type of Donation

Sandesh Raman Parajuli, Camille C. Ylagan, Dave Patel, Paul E. Schindler et autres

Background. Increased use of pediatric donors or donation after circulatory death (DCD) donors could enlarge the pancreas transplant donor pool. Pediatric donors and DCD donors are underutilized but are associated with similar outcomes following simultaneous pancreas and kidney (SPK) transplantation, compared with …

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Importing pancreata for transplantation: a single-center experience across evolving allocation eras

Riccardo Tamburrini, Stacey Hidalgo, GLEN E. LEVERSON, Dixon B. Kaufman et autres

Recent changes to allocation systems have increased the geographic distribution of pancreas offers, often originating from outside a transplant center's donor service area or region. The impact of this wider sharing on outcomes remains uncertain. This study analyzed outcomes of primary pancreas …

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A Multicenter Study of Weight Loss and Side Effects in Pancreas Transplant Recipients Treated with GLP-1 Receptor Agonists

Ali Abbasi, Giulia Worner, Riccardo Tamburrini, Brad C. Astor et autres

Purpose: Obesity in pancreas transplant recipients is a critical challenge due to the increasing prevalence in this population and association between obesity and insulin resistance. GLP-1 receptor agonists (GLP-1RA) have the potential to revolutionize obesity therapy, but safety and efficacy in pancreas …

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Pediatric donors in pancreas transplantation: challenges and opportunities

Riccardo Tamburrini, Jon S. Odorico

PURPOSE OF REVIEW: The purpose of this review is to provide a comprehensive analysis of the current literature on pediatric donors for pancreas transplantation, with a focus on donor selection, clinical outcomes and surgical approaches. This review aims to highlight the feasibility …

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Comprehensive biocompatibility profiling of human pancreas-derived biomaterial

Amish Asthana, Amanda Gallego, Quentin Perrier, Tamara Lozano‐Fernández et autres

Introduction The importance of the extracellular matrix (ECM) to pancreatic islets has been clearly demonstrated, as isolated islets grown in culture or transplanted, quickly lose viability and function after their matrix associations have been stripped away during the isolation process. Therefore, recapitulating …

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Total Pancreatectomy and Islet Autotransplantation for Chronic Pancreatitis Relieves Pain and Mitigates Diabetes Development.

Carrie Thiessen, Peter J. Chlebeck, Nancy Radke, Riccardo Tamburrini et autres

INTRODUCTION: By removing the intrinsic source of pain, total pancreatectomy offers patients with chronic pancreatitis a definitive surgical treatment. However, pancreatectomy results in labile diabetes. Specialized centers perform total pancreatectomy and islet autotransplantation (TP-IAT) to prevent labile diabetes and restore insulin independence …

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Simultaneous en bloc kidney and pancreas transplantation from pediatric donors: Selection, surgical strategy, management, and outcomes

Riccardo Tamburrini, Ching‐Yao Yang, Jennifer L. Philip, Nikole A. Neidlinger et autres

Pediatric donors are underutilized for simultaneous pancreas-kidney transplantation due to concerns about technical complications and inadequate islet and/or renal mass. We analyzed our experience with simultaneous en bloc kidney and pancreas transplantation using pediatric donors on 8 consecutive adult patients from 1997-2018. …

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Risk Factors for Developing Advanced Chronic Kidney Disease in Pancreas Transplant Alone Recipients

Sandesh Raman Parajuli, Emily E. Zona, Isabel C. Breyer, Riccardo Tamburrini et autres

BACKGROUND: Pancreas transplant alone (PTA) patients may progress to develop advanced chronic kidney disease (CKD). This study seeks to identify pretransplant factors among PTA recipients that predict progression to advanced CKD. METHODS: All primary PTA transplanted at our center >22 y were …

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Risk Factors for Early Post-transplant Weight Changes Among Simultaneous Pancreas-kidney Recipients and Impact on Outcomes

Sandesh Raman Parajuli, Riccardo Tamburrini, Fahad Aziz, Ban E. Dodin et autres

Background: There are limited data about the risk factors for weight changes and the association of significant weight changes with graft and metabolic outcomes after simultaneous pancreas and kidney (SPK) transplantation. Methods: We included all SPK recipients with both allografts functioning for …

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Simultaneous Pancreas-Kidney Transplant Outcomes Stratified by Autoantibodies Status and Pretransplant Fasting C-peptide

Sandesh Raman Parajuli, Riccardo Tamburrini, Fahad Aziz, Ban E. Dodin et autres

Backgrounds. Pancreatic beta cell function and islet autoantibodies classically distinguish types of diabetes (type 1 diabetes mellitus [DM] or type 2 DM). Here, we sought to evaluate simultaneous pancreas-kidney (SPK) transplant outcomes stratified by the presence or absence of beta cell function …

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Innate immune modulation in transplantation: mechanisms, challenges, and opportunities

Corinne E. Praska, Riccardo Tamburrini, Juan Sebastian Danobeitia

Organ transplantation is characterized by a sequence of steps that involve operative trauma, organ preservation, and ischemia-reperfusion injury in the transplant recipient. During this process, the release of damage-associated molecular patterns (DAMPs) promotes the activation of innate immune cells via engagement of …

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