Mariana R. Carvalho

Biomimetic villi-crypt scaffold-on-chip with tunable mechanical properties for intestinal epithelium modeling

Lorenzo Zavagna, Marta R. Casanova, Lara Pierantoni, Mariana R. Carvalho et autres

The small intestine possesses a complex architecture and microenvironment. Current in vitro three-dimensional models fail to fully replicate the architectural, biophysical and biochemical cues in both healthy and pathological intestine tissues. In this study, we designed and engineered a biomimetic villi-crypt scaffold-on-chip …

it, pt (code pays fourni par la source)

Gellan Gum-based Bioink for Bioprinting of a Mechanically Mimetic 3D in vitro Liver Model

Natália Akemi Kohori, Ibrahim Fatih Cengiz, Mariana R. Carvalho, Joana Silva‐Correia et autres

br, pt (code pays fourni par la source)

Biomimetic and soft lab-on-a-chip platform based on enzymatic-crosslinked silk fibroin hydrogel for 3D cell co-culture

Mariana R. Carvalho, David Conde Caballero, Subhas Chandra Kundu, Rui Luís Reis et autres

Abstract Integrating biological material within soft microfluidic systems made of hydrogels offers countless possibilities in biomedical research to overcome the intrinsic limitations of traditional microfluidics based on solid, non-biodegradable, and non-biocompatible materials. Hydrogel-based microfluidic technologies have the potential to transform in vitro …

pt (code pays fourni par la source)

Effectiveness of nutritional counseling with overweight pregnant women on child growth at 6 months: A randomized controlled trial

Izabela da Silva Santos, Mariana R. Carvalho, Naiara Franco Baroni, Lívia Castro Crivellenti et autres

br (code pays fourni par la source)

Evaluation of Novel Dendrimer–Gold Complex Nanoparticles for Theranostic Application in Oncology

Nevena N. Milivojević, Mariana R. Carvalho, David Conde Caballero, Snežana Radisavljević et autres

AIM: Despite some successful examples of therapeutic nanoparticles reaching clinical stages, there is still a significant need for novel formulations in order to improve the selectivity and efficacy of cancer treatment. METHODS: The authors developed two novel dendrimer-gold (Au) complex-based nanoparticles using …

rs, pt (code pays fourni par la source)

Microfluidic engineering of silk fibroin biomaterial

David Conde Caballero, Catarina M. Abreu, Mariana R. Carvalho, Joaquím M. Oliveira et autres

pt (code pays fourni par la source)

List of contributors

Catarina M. Abreu, Prachi Agarwal, Olatunji Ajiteru, Antonio Alessandrino et autres

pt, in, kr, it, ir, au, th, cn, gb, hk, es (code pays fourni par la source)

Hydrogels for microfluidics

Mariana R. Carvalho, Rui Luís Reis, Joaquím M. Oliveira

pt (code pays fourni par la source)

List of Contributors

Maria Elena Alemán‐Domínguez, Luigi Ambrosio, Nasim Annabi, N. A. M. Araújo et autres

es, it, us, pt, gb, in, de, ie, kr (code pays fourni par la source)

Gastrointestinal organs and organoids-on-a-chip: advances and translation into the clinics

Mariana R. Carvalho, Leping Yan, Bo Li, Changhua Zhang et autres

Abstract Microfluidic organs and organoids-on-a-chip models of human gastrointestinal systems have been established to recreate adequate microenvironments to study physiology and pathophysiology. In the effort to find more emulating systems and less costly models for drugs screening or fundamental studies, gastrointestinal system …

pt, cn (code pays fourni par la source)

Electroconductive poly(3,4-ethylenedioxythiophene) (PEDOT) nanoparticle-loaded silk fibroin biocomposite conduits for peripheral nerve regeneration

Ane Escobar, Aleksandra Serafin, Mariana R. Carvalho, Mario Alberto Gómez Culebras et autres

Abstract Peripheral nerve injury (PNI) often clinically relies on the use of nerve grafts taken from the patient to establish a therapeutic effect, though secondary site of injury and morbidity have prompted the medical community to find alternative solutions. A new trend …

pt, ie, es (code pays fourni par la source)

Longitudinally aligned inner-patterned silk fibroin conduits for peripheral nerve regeneration

Ane Escobar, Mariana R. Carvalho, Tiago Henriques Silva, Rui Luís Reis et autres

Peripheral nerve injuries represent a major clinical challenge, if nerve ends retract, there is no spontaneous regeneration, and grafts are required to proximate the nerve ends and give continuity to the nerve. The nerve guidance conduits (NGCs) presented in this work are …

es, pt (code pays fourni par la source)