Krishna Gavvala

Sustainable protein-derived fluorescent carbon dots for sensitive Hemoglobin detection and bioimaging

Jyoti Vishwakarma, Nitisha Beniwal, Arvind Kumar Rengan, Krishna Gavvala

in (code pays fourni par la source)

Photophysical tuning of fluorinated benzimidazole fluorophores: Donor-acceptor systems and BSA interactions

Jyoti Vishwakarma, Mayur B. Suryawanshi, Dineshbabu Takkella, Siddhant A.Kale et autres

in, pl (code pays fourni par la source)

Modulation of cellulase stability and activity by betaine- and choline-polyol based deep eutectic solvents

Madushmita Hatimuria, Jyoti Vishwakarma, V P Ananya, Anjali Anil et autres

in, pl (code pays fourni par la source)

Surface-controlled PET in corrole-graphene hybrid composites

Dineshbabu Takkella, Jyoti Vishwakarma, Mohammed Shamil O, Kolleboyina Jayaramulu et autres

in (code pays fourni par la source)

Structural and Energetic Analysis of Lenacapavir Binding to Human Serum Albumin: A Computational Study Using Docking, Molecular Dynamics, and MMPBSA/MMGBSA

Dineshbabu Takkella, Lakshmana Valipalli, Lakshmi V. R. Babu Syamala, Krishna Gavvala

ABSTRACT Human immunodeficiency virus (HIV) remains one of the deadliest pandemics, targeting white blood cells and weakening the immune system. Lenacapavir (LEN), a long‐acting HIV‐1 capsid inhibitor, has shown remarkable efficacy when administered via subcutaneous injection. Since injectable drugs interact with blood …

in (code pays fourni par la source)

Unraveling the mechanism of graphene oxide-mediated disruption of protein dimers

Jyoti Vishwakarma, Dineshbabu Takkella, Sudhanshu Sharma, Abhinav Srivastava et autres

regions with oxygen groups form hydrogen bonds and interact with polar residues of β-LG. This study combines experimental and computational approaches to offer a comprehensive understanding of the role of GO on biomolecules, contributing to the broader evaluation of nanomaterial effects in …

in, pl (code pays fourni par la source)

Laccase stability and activity in diol-based deep eutectic solvents: An experimental and computational study

Madushmita Hatimuria, Jyoti Vishwakarma, C Nikesh Chandran, Krishna Gavvala et autres

in (code pays fourni par la source)

Deciphering Structural Dynamics of DNA-Surfactant Interactions Using the Isomorphic Nucleobase Analogue

Dineshbabu Takkella, Krishna Gavvala

The interaction between DNA and surfactants plays an important role in exploring gene regulation, drug delivery, and nanotechnology. However, the specific interactions with the cationic surfactant leading to the conformational changes in DNA are mainly unknown. This study examines the structure and …

in (code pays fourni par la source)

Effect of PEG-Induced Liquid–Liquid Phase Separation on DNA–Topotecan Interactions

Dineshbabu Takkella, Jyoti Vishwakarma, Krishna Gavvala

Understanding the impact of liquid-liquid phase separation (LLPS) on drug and biological molecules is key to advancing drug delivery and biomolecular engineering. This study investigates how polyethylene glycol (PEG)-induced LLPS modulates the photophysical behavior of topotecan (TPT) and the structural organization of …

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Harnessing Deep Eutectic Solvents for Greener Medium Engineering and Enhanced Cellulase Activity

Madushmita Hatimuria, Jyoti Vishwakarma, V P Ananya, Nicola Della Ca’ et autres

The growing depletion of fossil fuels and climate concerns have spurred interest in renewable biomass, particularly lignocellulosic biomass (LCB), as a sustainable feedstock for biofuel production. Among its components, cellulose is a major target for enzymatic hydrolysis due to its potential to …

in (code pays fourni par la source)

Decoding the base flipping mechanism of the SET- and RING-associated (SRA) domain of the epigenetic UHRF1 protein

Dipanjan Mukherjee, Stefano Ciaco, Lara Martínez‐Fernández, Krishna Gavvala et autres

Ubiquitin-like, containing PHD and RING fingers domains 1 (UHRF1) plays a pivotal role in replicating DNA methylation patterns during cell division. Acting as a DNA reader, UHRF1, via its SET- and RING-associated (SRA) domain, recognizes hemi-methylated (HM) CpG sites and flips 5-methylcytosine …

fr, it, es, us (code pays fourni par la source)

Carbazole-rhodanine conjugate acts as an effective fluorescence biomarker for protein structural dynamics studies

Dineshbabu Takkella, Satheesh Ellipilli, Krishna Gavvala

in (code pays fourni par la source)