Wolfram Klemm

Effect of Celecoxib vs Placebo as Adjuvant Therapy on Disease-Free Survival Among Patients With Breast Cancer

R. Charles Coombes, Holly Tovey, Lucy Kilburn, Janine Mansi et autres

IMPORTANCE: Patients with breast cancer remain at risk of relapse after adjuvant therapy. Celecoxib has shown antitumor effects in preclinical models of human breast cancer, but clinical evidence is lacking. OBJECTIVE: To evaluate the role of celecoxib as an addition to conventional …

gb, au, ca, de (code pays fourni par la source)

Penetrating chest trauma caused by a blank cartridge actuated rubber ball projectile: case presentation and ballistic investigation of an uncommon weapon type

Matthias Frank, Dieter Peters, Wolfram Klemm, Rico Großjohann et autres

de (code pays fourni par la source)

Transoral endoscopic mediastinal surgery (TOEMS)—results of a first clinical study for scarless mediastinal lymph node biopsies

Wolfram Klemm, Steffen Frese, Gunda Leschber, André T. Nemat et autres

BACKGROUND: Video-assisted mediastinoscopy (VAM) represents the standard procedure for mediastinal lymph node biopsies. This operation results in a scar at prominent position at the anterior neck. Since there is a trend to less invasive procedures, natural orifice transluminal endoscopic surgery (NOTES) was …

de (code pays fourni par la source)

P-228RESULTS OF A PHASE I, PROOF-OF-CONCEPT STUDY FOR MEDIASTINAL LYMPH NODE-BIOPSIES BASED ON TRANSORAL ENDOSCOPIC SURGERY

Wolfram Klemm, AT Nemat, Gunda Leschber, T Wilhelm

Objectives: Video-assisted mediastinoscopy (VAM) represents the standard operating procedure for mediastinal lymph node biopsies. However, there are limitations to the procedure. Younger patients, in particular, might be affected by the scar in the frontal neck region. We therefore developed a transoral approach …

de (code pays fourni par la source)

Ergebnisse einer Phase I Machbarkeitsstudie zur Durchführung von mediastinalen Lymphknotenbiopsien mittels transoraler endoskopischer Mediastinalchirurgie (TOEMS)

Wolfram Klemm, AT Nemat, T Wilhelm

Zielsetzung: Die videoassistierte Mediastinoskopie (VAM) stellt heute das chirurgische Standardverfahren zur mediastinalen Lymphknotenbiospie dar. Wir haben in der Vergangenheit einen transoralen Zugangsweg für diese Operation (TOEMS) im Tiermodel und an der Leiche entwickelt. Unklar ist, ob beim Patienten der transorale Zugangsweg eine …

de (code pays fourni par la source)

Korrelation der Komplikationsrate mit dem Resektionsausmaß bei Tracheateilresektionen

AE Frick, S Frese, Mareike Graff, Wolfram Klemm et autres

Zielsetzung: Die Tracheateilresektion ist heutzutage das Therapieverfahren der Wahl in der Behandlung symptomatischer Trachealstenosen. Unklar ist, ob und inwieweit der postoperative Verlauf vom Resektionsausmaß beeinflusst wird. Methode: Retrospektive Analyse aller Patienten, die von 2004 bis 2014 in unserer Thoraxchirurgischen Klinik aufgrund einer …

de (code pays fourni par la source)

Prospective multicentre study on antimicrobial resistance of Helicobacter pylori in Germany

Nicole Wüppenhorst, S. Draeger, Hans‐Peter Stüger, Beate Hobmaier et autres

OBJECTIVES: Antimicrobial resistance of Helicobacter pylori endangers the successful eradication of the bacteria. The aim of this prospective surveillance study (ResiNet) is to continuously keep antimicrobial resistance of H. pylori in Germany under surveillance and to identify risk factors for its development. …

de, at (code pays fourni par la source)

F-096DOES VIDEO-ASSISTED MEDIASTINOSCOPIC LYMPHADENECTOMY FULFIL CRITERIA TO BECOME A STANDARD PROCEDURE FOR EARLY STAGE LUNG CARCINOMA?

Barbara Erne, Wolfram Klemm, Mareike Graff, Gunda Leschber

Video-assisted mediastinoscopic lymphadenectomy (VAMLA) is a procedure for complete bilateral resection of mediastinal lymph nodes in stations 4, 10 and 7. Here, we present recent data on the use of VAMLA for mediastinal lymph node staging in early stage lung carcinoma. We …

Bulla in the lung

Barbara Erne, Mareike Graff, Wolfram Klemm, Johann G. Danzl et autres

de (code pays fourni par la source)

Neue Horizonte für die Mediastinoskopie: Entwicklung einer transoralen Mediastinal-Chirurgie auf der Basis von NOS (natural orifice surgery)

Wolfram Klemm, T Wilhelm, Gunda Leschber, Joris J. Harlaar et autres

Hintergrund: In den letzten Jahren ist die Minimalisierung der Zugangswege in den meisten chirurgischen Disziplinen rasch vorangeschritten und hat ihren vorläufigen Höhepunkt in den Techniken über natürliche Körperöffnungen (NOS) gefunden. Ziel dieser Bemühungen ist die Verminderung des chirurgischen Traumas unter Erhalt oder …

de, nl (code pays fourni par la source)

Development of a new trans-oral endoscopic approach for mediastinal surgery based on ‘natural orifice surgery’: preclinical studies on surgical technique, feasibility, and safety

Thomas Wilhelm, Wolfram Klemm, Gunda Leschber, Joris J. Harlaar et autres

OBJECTIVE: In recent years, several surgical disciplines adopted endoscopic techniques. Presently, natural orifice approaches are under exploration to reduce surgical access trauma. We have developed a trans-oral endoscopic approach for endoscopic mediastinal surgery and have tested this new technique in preclinical studies …

de, nl (code pays fourni par la source)

Video-mediastinoscopic resection of a long bronchial stump and reclosure of bronchial insufficiency after pneumonectomy

Gunda Leschber, Wolfram Klemm, Johannes Merk

Bronchial stump insufficiency after pneumonectomy is a severe problem and there is still debate about the appropriate method (transthoracic or transsternal) for reclosure. Access through a sterile operative field for a successful redo-procedure seems to be important so an alternative to the …