J Hrnciar

Prevalence of metabolic syndrome, insulin resistance, and microvascular angina pectoris in 500 consecutive patients referred to coronarography

J Hrnciar, Mária Avdičová, D Gábor, M Hrnčiarová et autres

OBJECTIVE: This work was aimed to evaluate the prevalence of insulin resistance (IR) and metabolic syndrome in a large cohort of 40-60 years old patients with cardiovascular symptoms. METHODS: A total of 500 consecutive males and females referred to coronarography and coronary …

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[Thyrotoxic heart disease. Part II--aspects of treatment of thyrotoxicosis with cardiac involvement].

J Hrnciar

In the treatment of the thyrotoxic heart a radical, early thyroeliminating procedure should have preference. As the method of first choice a single administration of a whole calculated dose of I131 is recommended without previous medicamentous preparation up to 25-30 mCie which …

[Cor thyreotoxicum. Part I--new findings about its etiopathogenesis and diagnosis. Overview of problems based on 35 years' experience].

J Hrnciar

In the seventies thyrotoxic heart accounted for 3% of all hospitalized cardiac patients and was found on average in 30% of all cases of hyperthyroidism. It presented most frequently by tachyfibrillation and resistant cardiac decompensation. It affected men four times as frequently …

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[Thallium scintigraphy of the myocardium in evaluation of patients with insulin resistance syndrome and microvascular angina pectoris].

J Lepej, D Spisiaková, J Hrnciar, J Okapcová et autres

Insulin resistance syndrom (IR) is often associated with the syndrome of microvascular angina pectoris (MVAP) or with coronary artery disease (CAD). The authors quantified distribution and washout of 201Tl in heart (C), lungs (L) and liver (H) to evaluate the results 201Tl …

sk (code pays fourni par la source)

[Is the existence of integrated internists necessary and why?].

J Hrnciar

[Functions and dysfunctions of the vascular endothelium].

J Hrnciar, J Okapcová, D Gábor

Endothelium represents a large paracrine gland with an enormous reactive surface. By means of its numerous vasodilation and vasospastic factors it manages the basal and working tonus of vessels and thus also the regional flow and the access of target tissues to …

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[Homocysteine--a routine biochemical parameter in cardiovascular diseases?].

D Gábor, J Hrnciar, I Hricová, Mária Zacharová

An elevated level of total homocysteine (tHcy) in blood-hyperhomocysteinemia, is prevalent and strong risk factor for atherosclerotic vascular disease in the coronary, cerebral and peripheral vessels and for thromboembolism (arterial and venous). Elevated total homocysteine confers a graded risk with no threshold, …

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[Insulin resistance and the coronary syndrome].

J Okapcová, J Hrnciar, František Kovář, Peter Kurray et autres

The different diseases associated with the insulin resistance syndrome--diabetes mellitus or impaired carbohydrate tolerance, atherogenic lipoprotein phenotype, arterial hypertension and central type of obesity are the main risk factors of atherosclerosis. The reduced sensitivity of target tissues to the metabolic action of …

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[Occurrence of primary aldosteronism in a group of ambulatory hypertensive patients].

A Kréze, D Okálová, Peter Vaňuga, Zsuzsanna Putz et autres

Findings pertaining to the diagnosis and treatment of primary aldosteronism are rapidly expanding. In the present work the authors focused attention on the clinical application of some progressive methods. They examined a group of 115 ambulatory patients with arterial hypertension, not suspected …

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[Relation between cytokines (TNF-alpha, IL-1 and 6) and homocysteine in android obesity and the phenomenon of insulin resistance syndromes].

J Hrnciar, D Gábor, M Hrnčiarová, J Okapcová et autres

TNF-alpha (so-called cachectin), IL-1 and 6 are important regulating agents in the homeostasis of energy in the organism, as among others they control processes of apoptosis and thus also the volume of adipose and muscular tissues. They are produced not only in …

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[Relation between levels of leptin, insulin and cortisol in persons with the 5H (X) syndrome].

J Hrnciar, J Okapcová, J Lepej, D Gábor

Leptin levels in subjects with android obesity with the insulin resistance syndrome (syndrome X, 5H) are in general elevated, as compared with non-obese subjects and correlate with the BMI, with the percentage of body fat, WHR, IRI levels and sex (they are …

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[The polycystic ovary syndrome and insulin resistance].

A Kréze, J Hrnciar, M Dobáková, E Pekarová

The insulin resistance syndrome and the polycystic ovary syndrome (PCOS) appear to have some following coincidences: the existence of subclinical acanthosis nigricans in PCOS hyperinsulinemic women, correlation of insulin levels and free testosterone, insulin-like growth factor I binding protein (IGFIBP), and sex-hormone …

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