Akwasi Agyeman

Supplementary Methods from Blocking Hedgehog Survival Signaling at the Level of the GLI Genes Induces DNA Damage and Extensive Cell Death in Human Colon Carcinoma Cells

Tapati Mazumdar, Jennifer DeVecchio, Akwasi Agyeman, Ting Shi et autres

PDF file - 75K

Supplementary Figure 2 from Blocking Hedgehog Survival Signaling at the Level of the GLI Genes Induces DNA Damage and Extensive Cell Death in Human Colon Carcinoma Cells

Tapati Mazumdar, Jennifer DeVecchio, Akwasi Agyeman, Ting Shi et autres

PDF file - 65K

Supplementary Figure 1 from Blocking Hedgehog Survival Signaling at the Level of the GLI Genes Induces DNA Damage and Extensive Cell Death in Human Colon Carcinoma Cells

Tapati Mazumdar, Jennifer DeVecchio, Akwasi Agyeman, Ting Shi et autres

PDF file - 34K

Supplementary Methods from Blocking Hedgehog Survival Signaling at the Level of the GLI Genes Induces DNA Damage and Extensive Cell Death in Human Colon Carcinoma Cells

Tapati Mazumdar, Jennifer DeVecchio, Akwasi Agyeman, Ting Shi et autres

PDF file - 75K

Supplementary Figure 2 from Blocking Hedgehog Survival Signaling at the Level of the GLI Genes Induces DNA Damage and Extensive Cell Death in Human Colon Carcinoma Cells

Tapati Mazumdar, Jennifer DeVecchio, Akwasi Agyeman, Ting Shi et autres

PDF file - 65K

Supplementary Figure 1 from Blocking Hedgehog Survival Signaling at the Level of the GLI Genes Induces DNA Damage and Extensive Cell Death in Human Colon Carcinoma Cells

Tapati Mazumdar, Jennifer DeVecchio, Akwasi Agyeman, Ting Shi et autres

PDF file - 34K

Data from Blocking Hedgehog Survival Signaling at the Level of the GLI Genes Induces DNA Damage and Extensive Cell Death in Human Colon Carcinoma Cells

Tapati Mazumdar, Jennifer DeVecchio, Akwasi Agyeman, Ting Shi et autres

Abstract Canonical Hedgehog (HH) signaling is characterized by Smoothened (Smo)-dependent activation of the transcription factors Gli1 and Gli2, which regulate HH target genes. In human colon carcinoma cells, treatment with the Gli small-molecule inhibitor GANT61 induces extensive cell death in contrast to …

Data from Blocking Hedgehog Survival Signaling at the Level of the GLI Genes Induces DNA Damage and Extensive Cell Death in Human Colon Carcinoma Cells

Tapati Mazumdar, Jennifer DeVecchio, Akwasi Agyeman, Ting Shi et autres

Abstract Canonical Hedgehog (HH) signaling is characterized by Smoothened (Smo)-dependent activation of the transcription factors Gli1 and Gli2, which regulate HH target genes. In human colon carcinoma cells, treatment with the Gli small-molecule inhibitor GANT61 induces extensive cell death in contrast to …

ABCL-509 Healthcare Utilization and Costs in Chimeric Antigen Receptor T-Cell Therapy for B-Cell Lymphoma

Nathan Denlinger, Ying Huang, Zachary Braunstein, Audrey M. Sigmund et autres

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Poster: ABCL-509 Healthcare Utilization and Costs in Chimeric Antigen Receptor T-Cell Therapy for B-cell Lymphoma

Nathan Denlinger, Ying Huang, Zachary Braunstein, Audrey M. Sigmund et autres

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Fluoroquinolone Prophylaxis in Autologous Stem Cell Transplantation: Worthy of a Second Look

Joseph Maakaron, Christina Liscynesky, Zeinab El Boghdadly, Ying Huang et autres

Prophylaxis with fluoroquinolone (FQ) for patients undergoing autologous stem cell transplantation (ASCT) remains controversial. We performed a retrospective review of patients undergoing ASCT with and without bacterial prophylaxis to compare endpoints of interest. In accordance with institutional policy, patients undergoing ASCT for …

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CAR T-Cell Therapy: Clinical Outcomes, Patient Selection and Financial Metrics with Tisagenlecleucel and Axicabtagene Ciloleucel, a Single Center Experience

Nathan Denlinger, Zachary Braunstein, Akwasi Agyeman, Zebulun Purdin et autres

Background Axicabtagene ciloleucel (A) and Tisagenlecleucel (T) are FDA approved CAR T cell products that have changed treatment (tx) for patients (pts) w/ relapsed/refractory lymphoma. The high tx cost has implications in selection of pts for CAR T and data comparing these …

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